PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID EMT09387
Organism
Aegilops tauschii
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; Liliopsida; Petrosaviidae; commelinids; Poales; Poaceae; BOP clade; Pooideae; Triticodae; Triticeae; Triticinae; Aegilops
Family E2F/DP
Protein Properties Length: 393aa    MW: 43780.4 Da    PI: 8.432
Description E2F/DP family protein
Gene Model
Gene Model ID Type Source Coding Sequence
EMT09387genomeBGIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1E2F_TDP72.35.4e-2344109171
   E2F_TDP   1 rkeksLrlltqkflkllekseegivtlnevakeLvsedvknkrRRiYDilNVLealnliekkekneirwkg 71 
               rk+ksL+ll+++f++l+ + + ++v l+++a++L    v  +rRRiYDi+NVLe+++++ +++kn+++w+g
  EMT09387  44 RKQKSLGLLCSNFVALYDRDDVETVGLDDAARRL---GV--ERRRIYDIVNVLESVGILVRRAKNRYTWIG 109
               79****************9999************...**..****************************98 PP
2E2F_TDP78.94.8e-25168248171
   E2F_TDP   1 rkeksLrlltqkflkllekseegivtlnevakeLvse.....dvknkrRRiYDilNVLealnliek.....kekneirwkg 71 
               rkeksL+lltq+f+kl+ + e ++v+l+e+a+ L+ e     ++++k+RR+YDi+NVL++lnliek     ++k+++rw g
  EMT09387 168 RKEKSLGLLTQNFVKLFLTMEVETVSLDEAARLLLGErhaesNMRTKVRRLYDIANVLSSLNLIEKtqqvdSRKPAFRWLG 248
               79****************************************************************9999999******87 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:1.10.10.101.5E-2540110IPR011991Winged helix-turn-helix DNA-binding domain
SuperFamilySSF467851.18E-1643108IPR011991Winged helix-turn-helix DNA-binding domain
SMARTSM013728.6E-2944109IPR003316E2F/DP family, winged-helix DNA-binding domain
PfamPF023196.7E-2145109IPR003316E2F/DP family, winged-helix DNA-binding domain
Gene3DG3DSA:1.10.10.102.9E-23165249IPR011991Winged helix-turn-helix DNA-binding domain
SMARTSM013721.4E-32168248IPR003316E2F/DP family, winged-helix DNA-binding domain
PfamPF023192.6E-20169248IPR003316E2F/DP family, winged-helix DNA-binding domain
SuperFamilySSF467859.79E-13170248IPR011991Winged helix-turn-helix DNA-binding domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0005634Cellular Componentnucleus
GO:0005667Cellular Componenttranscription factor complex
GO:0003677Molecular FunctionDNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 393 aa     Download sequence    Send to blast
MDPAATPPPP PPPPPYLPPR LVIDGAGGGS GAAARACRHH ASSRKQKSLG LLCSNFVALY  60
DRDDVETVGL DDAARRLGVE RRRIYDIVNV LESVGILVRR AKNRYTWIGF EGVPAALKEL  120
KVSDDEDDDD KLGDADGDAD SEKLSQSIDN ASDKPDTPMC PRRSVDHRKE KSLGLLTQNF  180
VKLFLTMEVE TVSLDEAARL LLGERHAESN MRTKVRRLYD IANVLSSLNL IEKTQQVDSR  240
KPAFRWLGQA KRKEGATVTV ALPPARKIMS SKRAFGTDIT NIDNKRGKLV LETENKPKLM  300
QGGSSMLKTF ESQLGQGKSS GFVYGPFHPA GARKHEVDDQ TVRENETKNI QDWENLAVSF  360
RPQYQNHALN DLFGHYVEAW KSWYLDLTRE STS
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
4yo2_A2e-39432403228Transcription factor E2F8
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtInhibitor of E2F-dependent activation of gene expression. Binds specifically the E2 recognition site without interacting with DP proteins and prevents transcription activation by E2F/DP heterodimers. Controls the timing of endocycle onset and inhibits endoreduplication. {ECO:0000269|PubMed:11786543, ECO:0000269|PubMed:11867638, ECO:0000269|PubMed:15649366, ECO:0000269|PubMed:18787127}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankAK3753580.0AK375358.1 Hordeum vulgare subsp. vulgare mRNA for predicted protein, complete cds, clone: NIASHv3092B12.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_020187543.10.0E2F transcription factor-like E2FE isoform X1
SwissprotQ8LSZ41e-104E2FE_ARATH; E2F transcription factor-like E2FE
TrEMBLM8AY340.0M8AY34_AEGTA; Transcription factor E2F7
STRINGEMT093870.0(Aegilops tauschii)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MonocotsOGMP31853884
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT3G48160.21e-99DP-E2F-like 1
Publications ? help Back to Top
  1. Chandran D, et al.
    Atypical E2F transcriptional repressor DEL1 acts at the intersection of plant growth and immunity by controlling the hormone salicylic acid.
    Cell Host Microbe, 2014. 15(4): p. 506-13
    [PMID:24721578]
  2. Wang Z, et al.
    Del1 Knockout Mice Developed More Severe Osteoarthritis Associated with Increased Susceptibility of Chondrocytes to Apoptosis.
    PLoS ONE, 2016. 11(8): p. e0160684
    [PMID:27505251]
  3. Heyman J,Polyn S,Eekhout T,De Veylder L
    Tissue-Specific Control of the Endocycle by the Anaphase Promoting Complex/Cyclosome Inhibitors UVI4 and DEL1.
    Plant Physiol., 2017. 175(1): p. 303-313
    [PMID:28698355]