PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID EMT14050
Organism
Aegilops tauschii
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; Liliopsida; Petrosaviidae; commelinids; Poales; Poaceae; BOP clade; Pooideae; Triticodae; Triticeae; Triticinae; Aegilops
Family EIL
Protein Properties Length: 648aa    MW: 71448 Da    PI: 4.8599
Description EIL family protein
Gene Model
Gene Model ID Type Source Coding Sequence
EMT14050genomeBGIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1EIN3508.14e-155794661354
               XXXXXXXXXXXXXXXXXXXXXXX..XXXXX.....XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX CS
      EIN3   1 eelkkrmwkdqmllkrlkerkkqlledkeaa....tgakksnksneqarrkkmsraQDgiLkYMlkemevcnaqGfvYgiipekgkpvegasdsLraWWke 97 
               eel++rmw+d+m+lkrlke ++++ +++ a      +  k ++s+eqarrkkmsraQDgiLkYMlk+mevc+aqGfvYgiipekgkpv+gasd+LraWWke
  EMT14050  79 EELERRMWRDRMKLKRLKELQQSRGKEQAAGgggvGDGLKPRQSQEQARRKKMSRAQDGILKYMLKMMEVCRAQGFVYGIIPEKGKPVSGASDNLRAWWKE 179
               8*********************9875555558888788899************************************************************ PP

               XXXXXXXXXXXXXXXXXXXXXXXXXXXX....XX----STTS-HHHHHHHHHHHSSSSSS-TTS--TTT--HHHH---S--HHHHHHT--TT--.-----G CS
      EIN3  98 kvefdrngpaaiskyqaknlilsgesslqtersseshslselqDTtlgSLLsalmqhcdppqrrfplekgvepPWWPtGkelwwgelglskdqgtppykkp 198
               kv+fdrngpaai+kyqa+n+++++es+l + +++++hsl+elqDTtlgSLLsalmqhcdppqrrfplekg++pPWWP+G+e+ww+elg++kdqg+ppykkp
  EMT14050 180 KVRFDRNGPAAIAKYQADNAVPGSESELAS-GTASPHSLQELQDTTLGSLLSALMQHCDPPQRRFPLEKGISPPWWPSGDEEWWPELGIPKDQGPPPYKKP 279
               ****************************66.********************************************************************** PP

               GG--HHHHHHHHHHHHHHTGGGHHHHHHTTTTSSSSTTT--SHHHHHHHHHHTTTTT-S--XXXXXX...XXXX..XXXXXXXXXXXXXXXXXXXXXX.XX CS
      EIN3 199 hdlkkawkvsvLtavikhmsptieeirelerqskylqdkmsakesfallsvlnqeekecatvsahss...slrk..qspkvtlsceqkedvegkkeskikh 294
               hdlkkawkvsvLtavikhmsp+ie+ir+l+rqsk+lqdkm+ake  ++l+v++qee+++ ++++  +   s     ++ ++++s++ ++dv+  ++ k  +
  EMT14050 280 HDLKKAWKVSVLTAVIKHMSPDIEKIRRLVRQSKCLQDKMTAKEISTWLAVVKQEEELFMRLHPGARppaSAGGiaSAISFNASSS-EYDVDLADDCKGDE 379
               ****************************************************************9443442222425555555555.99***666666666 PP

               XXXXXXXX............................XXXXXXXXXXXXXXXXXXXXX......XXXXXXX.XXXXXXXXXXXXXXXXX CS
      EIN3 295 vqavktta............................gfpvvrkrkkkpsesakvsskevsrtcqssqfrgsetelifadknsisqney 354
               + ++k ++                            +++ v+kr +  +e++ + +++v +tc++ q+++s++  +f d+n++s+++y
  EMT14050 380 AGTHKMAMadptafnlgaailndkflmqapmkeetaDMEYVQKRSAVAAEPELMLNNRV-YTCNNVQCPHSDYGYGFLDRNARSSHQY 466
               6666655577777******************************************9976.**************************98 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PfamPF048731.0E-13179335No hitNo description
Gene3DG3DSA:1.10.3180.105.9E-74209343IPR023278Ethylene insensitive 3-like protein, DNA-binding domain
SuperFamilySSF1167681.22E-60214339IPR023278Ethylene insensitive 3-like protein, DNA-binding domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0001666Biological Processresponse to hypoxia
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0009873Biological Processethylene-activated signaling pathway
GO:0042742Biological Processdefense response to bacterium
GO:0071281Biological Processcellular response to iron ion
GO:0005634Cellular Componentnucleus
GO:0000976Molecular Functiontranscription regulatory region sequence-specific DNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 648 aa     Download sequence    Send to blast
MMGGGLLMDQ GMAFSGVHNF VDLLQQNGAD KNLGFGSLMP QTSSGDQCVM GEGDLVDPPT  60
DNFPDAGEDD SDDDVDDIEE LERRMWRDRM KLKRLKELQQ SRGKEQAAGG GGVGDGLKPR  120
QSQEQARRKK MSRAQDGILK YMLKMMEVCR AQGFVYGIIP EKGKPVSGAS DNLRAWWKEK  180
VRFDRNGPAA IAKYQADNAV PGSESELASG TASPHSLQEL QDTTLGSLLS ALMQHCDPPQ  240
RRFPLEKGIS PPWWPSGDEE WWPELGIPKD QGPPPYKKPH DLKKAWKVSV LTAVIKHMSP  300
DIEKIRRLVR QSKCLQDKMT AKEISTWLAV VKQEEELFMR LHPGARPPAS AGGIASAISF  360
NASSSEYDVD LADDCKGDEA GTHKMAMADP TAFNLGAAIL NDKFLMQAPM KEETADMEYV  420
QKRSAVAAEP ELMLNNRVYT CNNVQCPHSD YGYGFLDRNA RSSHQYTCKY NDPLPPSAEN  480
KAAPPAPPQV FPAAYNQQNH GLNNLDFGLP MDGQRSIAEL MNMYDTAFPA TNKNMGNDDV  540
TIIERPNAIT PGAQMDEGFF GQGNGIGGNG DSMFSDVSNM MQQQQAQQPQ QQQAPAQQQF  600
FIRDDAQAQF GNQMGSISGA SDFRFGSGFN MSGTVDYPQK NDGPNWYY
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
4zds_A5e-742123431132Protein ETHYLENE INSENSITIVE 3
4zds_B5e-742123431132Protein ETHYLENE INSENSITIVE 3
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtTranscription factor acting as a positive regulator in the ethylene response pathway (PubMed:16786297, PubMed:28829777, PubMed:27701783, PubMed:25995326). Required for the inhibition of root growth by ethylene in etiolated seedlings (PubMed:25995326, PubMed:28829777). Functions upstream of the auxin biosynthetic gene YUCCA8 and directly activates its expression (PubMed:28829777). Functions downstream of the ethylene signaling factor EIN2 in disease resistance against the rice blast fungus (Magnaporthe oryzae) (PubMed:27701783). Binds directly to the promoters of the NADPH oxidases RBOHA and RBOHB, and the jasmonate biosynthetic gene OPR4 to activate their expression during fungal infection (PubMed:27701783). May enhance disease resistance by facilitating reactive oxygen species (ROS) generation and jasmonate biosynthesis with subsequent phytoalexin accumulation during Magnaporthe oryzae infection (PubMed:27701783). Acts as negative regulator of salt tolerance (PubMed:25995326). During salt stress, activates the cation transporter HKT1, which mediates increased sodium uptake in roots, and contributes to sodium accumulation and salt toxicity (PubMed:25995326). Binds directly to the DNA sequence 5'-TGTTACAAATACC-3' in the promoter of the GA20OX2 gene to activate its expression at the transcriptional level during ethylene signaling (PubMed:30002253). Possesses transactivation activity in protoplasts (PubMed:25995326). {ECO:0000269|PubMed:16786297, ECO:0000269|PubMed:25995326, ECO:0000269|PubMed:27701783, ECO:0000269|PubMed:28829777, ECO:0000269|PubMed:30002253}.
Binding Motif ? help Back to Top
Motif ID Method Source Motif file
MP00367DAPTransfer from AT3G20770Download
Motif logo
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Induced by infection with the fungal pathogen Magnaporthe oryzae. {ECO:0000269|PubMed:27701783}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieveRetrieve
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankKU0308370.0KU030837.1 Triticum aestivum ethylene insensitive 3-like product (TaEIL1) mRNA, complete cds.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_020198090.10.0ETHYLENE INSENSITIVE 3-like 1 protein
SwissprotQ10M410.0EIL1A_ORYSJ; Protein ETHYLENE-INSENSITIVE 3-like 1a
TrEMBLA0A453I6X40.0A0A453I6X4_AEGTS; Uncharacterized protein
TrEMBLN1QWK40.0N1QWK4_AEGTA; Protein ETHYLENE INSENSITIVE 3
STRINGEMT140500.0(Aegilops tauschii)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MonocotsOGMP63838168
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT2G27050.11e-157ETHYLENE-INSENSITIVE3-like 1
Publications ? help Back to Top
  1. Kikuchi S, et al.
    Collection, mapping, and annotation of over 28,000 cDNA clones from japonica rice.
    Science, 2003. 301(5631): p. 376-9
    [PMID:12869764]
  2. Yang C, et al.
    MAOHUZI6/ETHYLENE INSENSITIVE3-LIKE1 and ETHYLENE INSENSITIVE3-LIKE2 Regulate Ethylene Response of Roots and Coleoptiles and Negatively Affect Salt Tolerance in Rice.
    Plant Physiol., 2015. 169(1): p. 148-65
    [PMID:25995326]
  3. Yang C, et al.
    Activation of ethylene signaling pathways enhances disease resistance by regulating ROS and phytoalexin production in rice.
    Plant J., 2017. 89(2): p. 338-353
    [PMID:27701783]
  4. Qin H, et al.
    The activation of OsEIL1 on YUC8 transcription and auxin biosynthesis is required for ethylene-inhibited root elongation in rice early seedling development.
    PLoS Genet., 2017. 13(8): p. e1006955
    [PMID:28829777]
  5. Kuroha T, et al.
    Ethylene-gibberellin signaling underlies adaptation of rice to periodic flooding.
    Science, 2018. 361(6398): p. 181-186
    [PMID:30002253]