PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Home  TFext  BLAST  Prediction  Download  Help  About  Links  PlantRegMap
(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Eucgr.F04379.1.p
Common NameEUGRSUZ_F04379, LOC104450965
Organism
Eucalyptus grandis
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Myrtales; Myrtaceae; Myrtoideae; Eucalypteae; Eucalyptus
Family C2H2
Protein Properties Length: 448aa    MW: 51468.9 Da    PI: 7.7286
Description C2H2 family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Eucgr.F04379.1.pgenomeJGIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1zf-C2H2110.0013205227123
                       EEETTTTEEESSHHHHHHHHHHT CS
           zf-C2H2   1 ykCpdCgksFsrksnLkrHirtH 23 
                       y C+ C    +rk++L+rH++++
  Eucgr.F04379.1.p 205 YFCEFCLNFMKRKEQLQRHMKKC 227
                       78*******************98 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SuperFamilySSF541602.84E-2456172IPR016197Chromo domain-like
Gene3DG3DSA:2.30.30.2707.7E-3860132No hitNo description
PfamPF117172.3E-2162120IPR025995RNA binding activity-knot of a chromodomain
CDDcd000243.53E-775120No hitNo description
SMARTSM002983.4E-776135IPR000953Chromo/chromo shadow domain
Gene3DG3DSA:2.30.30.2707.7E-38166216No hitNo description
PROSITE profilePS5172675.867171442IPR002717Histone acetyltransferase domain, MYST-type
SuperFamilySSF557298.77E-112172443IPR016181Acyl-CoA N-acyltransferase
Gene3DG3DSA:3.40.630.308.0E-73230373IPR016181Acyl-CoA N-acyltransferase
PfamPF018538.9E-84232409IPR002717Histone acetyltransferase domain, MYST-type
CDDcd043010.00151283341No hitNo description
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006281Biological ProcessDNA repair
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0010224Biological Processresponse to UV-B
GO:0016573Biological Processhistone acetylation
GO:2000028Biological Processregulation of photoperiodism, flowering
GO:0005634Cellular Componentnucleus
GO:0043995Molecular Functionhistone acetyltransferase activity (H4-K5 specific)
Sequence ? help Back to Top
Protein Sequence    Length: 448 aa     Download sequence    Send to blast
MGSIDPPKAE QNGTAAAAVA DPGQKPGAGD AMPPPPPVKH SNGTAAEPDV ATKRRRMSVL  60
PLEVGTRVMC RWRDGKYHPV KVIERRKLNP GDPNDYEYYV HYTEFNRRLD EWVKLEQLDL  120
NSVETVVDEK VEDKVTGLKM TRHQKRKIDE THVEGHEELD AASLREHEEF TKVKNIATIE  180
LGRYEIETWY FSPFPPEYND CSKLYFCEFC LNFMKRKEQL QRHMKKCDLK HPPGDEIYRS  240
GTLSMFEVDG KKNKVYGQNL CYLAKLFLDH KTLYYDVDLF LFYVLCECDD RGCHMVGYFS  300
KEKHSEESYN LACILTLPPY QRKGYGKFLI AFSYELSKKE GKVGTPERPL SDLGLLSYKG  360
YWTRVLLDIL KKHKANISIK ELSDMTAIKA DDILNTLQSL DLIQYRKGQH VICADPKVLD  420
RHLKAAGRGG LEVDVSKLIW TPYREQG*
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
4dnc_A1e-1161674421278Histone acetyltransferase KAT8
4dnc_B1e-1161674421278Histone acetyltransferase KAT8
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtHistone acetyltransferase which may be involved in transcriptional activation. Acetylates 'Lys-5' of histone H4 (H4K5ac) (PubMed:17877703, PubMed:19040736, PubMed:22170978, PubMed:23273925). Essential for gametophyte development (PubMed:19040736). Involved in DNA repair after UV-B exposure (PubMed:22170978). Negative regulator of flowering controlling the H4K5ac levels in the FLC chromatin (PubMed:23273925). {ECO:0000269|PubMed:17877703, ECO:0000269|PubMed:19040736, ECO:0000269|PubMed:22170978, ECO:0000269|PubMed:23273925}.
Cis-element ? help Back to Top
SourceLink
PlantRegMapEucgr.F04379.1.p
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Up-regulated upon UV-B exposure. {ECO:0000269|PubMed:22170978}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_010064005.10.0PREDICTED: histone acetyltransferase of the MYST family 1
SwissprotQ9FLF70.0MYST1_ARATH; Histone acetyltransferase of the MYST family 1
TrEMBLA0A059BZ940.0A0A059BZ94_EUCGR; Histone acetyltransferase
STRINGXP_010064005.10.0(Eucalyptus grandis)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MalvidsOGEM480656
Publications ? help Back to Top
  1. Latrasse D, et al.
    The MYST histone acetyltransferases are essential for gametophyte development in Arabidopsis.
    BMC Plant Biol., 2008. 8: p. 121
    [PMID:19040736]
  2. Campi M,D'Andrea L,Emiliani J,Casati P
    Participation of chromatin-remodeling proteins in the repair of ultraviolet-B-damaged DNA.
    Plant Physiol., 2012. 158(2): p. 981-95
    [PMID:22170978]
  3. Bari A,Orazova S,Ivashchenko A
    miR156- and miR171-binding sites in the protein-coding sequences of several plant genes.
    Biomed Res Int, 2013. 2013: p. 307145
    [PMID:23936788]
  4. Xu Y, et al.
    Arabidopsis MRG domain proteins bridge two histone modifications to elevate expression of flowering genes.
    Nucleic Acids Res., 2014. 42(17): p. 10960-74
    [PMID:25183522]
  5. Raevsky AV,Sharifi M,Samofalova DA,Karpov PA,Blume YB
    3D structure prediction of histone acetyltransferase proteins of the MYST family and their interactome in Arabidopsis thaliana.
    J Mol Model, 2016. 22(11): p. 256
    [PMID:27709438]
  6. Fina JP,Masotti F,Rius SP,Crevacuore F,Casati P
    HAC1 and HAF1 Histone Acetyltransferases Have Different Roles in UV-B Responses in Arabidopsis.
    Front Plant Sci, 2017. 8: p. 1179
    [PMID:28740501]