PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Eucgr.K02883.1.p
Common NameEUGRSUZ_K02883, LOC104426302
Organism
Eucalyptus grandis
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Myrtales; Myrtaceae; Myrtoideae; Eucalypteae; Eucalyptus
Family E2F/DP
Protein Properties Length: 390aa    MW: 43853.2 Da    PI: 9.6751
Description E2F/DP family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Eucgr.K02883.1.pgenomeJGIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1E2F_TDP73.12.9e-232186171
           E2F_TDP  1 rkeksLrlltqkflkllekseegivtlnevakeLvsedvknkrRRiYDilNVLealnliekkekneirwkg 71
                      rk+ksL+ll+++fl+l+ ++  + + l+e+a++L    v  +rRRiYDi+NVLe+++++ +k+kn+++wkg
  Eucgr.K02883.1.p 21 RKQKSLGLLCSNFLRLYDREGVDLIGLDEAASRL---GV--ERRRIYDIVNVLESIGVLVRKAKNQYTWKG 86
                      79*****************999************...**..****************************98 PP
2E2F_TDP72.25.8e-23156236171
           E2F_TDP   1 rkeksLrlltqkflkllekseegivtlnevakeLvse.....dvknkrRRiYDilNVLealnliek.....kekneirwkg 71 
                       r+eksL+llt++f+k++ +s+  + +l+e+ak L+ +        +k+RR+YDi+NVL+++nliek     ++kn++rw g
  Eucgr.K02883.1.p 156 RREKSLGLLTRNFVKIFICSNVAVFSLDEAAKILLGDgqssiMRSTKVRRLYDIANVLSSMNLIEKthttdTRKNAFRWLG 236
                       689*************************************9844479********************************87 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:1.10.10.102.6E-251887IPR011991Winged helix-turn-helix DNA-binding domain
SuperFamilySSF467851.05E-152084IPR011991Winged helix-turn-helix DNA-binding domain
SMARTSM013723.2E-262186IPR003316E2F/DP family, winged-helix DNA-binding domain
PfamPF023196.4E-202286IPR003316E2F/DP family, winged-helix DNA-binding domain
Gene3DG3DSA:1.10.10.102.9E-23152237IPR011991Winged helix-turn-helix DNA-binding domain
SMARTSM013723.8E-30156236IPR003316E2F/DP family, winged-helix DNA-binding domain
PfamPF023199.8E-19158236IPR003316E2F/DP family, winged-helix DNA-binding domain
SuperFamilySSF467851.5E-12158237IPR011991Winged helix-turn-helix DNA-binding domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0032876Biological Processnegative regulation of DNA endoreduplication
GO:0005634Cellular Componentnucleus
GO:0005667Cellular Componenttranscription factor complex
GO:0003677Molecular FunctionDNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 390 aa     Download sequence    Send to blast
MASIPSVNPS ESLQKLPSYS RKQKSLGLLC SNFLRLYDRE GVDLIGLDEA ASRLGVERRR  60
IYDIVNVLES IGVLVRKAKN QYTWKGFGGI PGALKKLKEE GLRENFSVSN FASYNRVSDD  120
EEDDEVYSDP NISSQEDQSN PAPVLQASGS ATSDNRREKS LGLLTRNFVK IFICSNVAVF  180
SLDEAAKILL GDGQSSIMRS TKVRRLYDIA NVLSSMNLIE KTHTTDTRKN AFRWLGPREK  240
WTGSVDALII DDPKKRMFGT EITNTDFKRN KMSPLVEGVP NINSKAQKQS KNEKLIKELS  300
RSKSEQDSKE NSKSYQFGPF APHNIPKVIA SRTENRSTQH QPRDWQSLAS EYSPQYHNQA  360
LRDIFGHYTE AWKSWFSEVA GKSHSSADT*
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
4yo2_A6e-38202283228Transcription factor E2F8
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtInhibitor of E2F-dependent activation of gene expression. Binds specifically the E2 recognition site without interacting with DP proteins and prevents transcription activation by E2F/DP heterodimers. Controls the timing of endocycle onset and inhibits endoreduplication. {ECO:0000269|PubMed:11786543, ECO:0000269|PubMed:11867638, ECO:0000269|PubMed:15649366, ECO:0000269|PubMed:18787127}.
Binding Motif ? help Back to Top
Motif ID Method Source Motif file
MP00397DAPTransfer from AT3G48160Download
Motif logo
Cis-element ? help Back to Top
SourceLink
PlantRegMapEucgr.K02883.1.p
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieveRetrieve
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_010037603.10.0PREDICTED: E2F transcription factor-like E2FE isoform X1
SwissprotQ8LSZ41e-119E2FE_ARATH; E2F transcription factor-like E2FE
TrEMBLA0A059A7K90.0A0A059A7K9_EUCGR; Uncharacterized protein
STRINGXP_010037603.10.0(Eucalyptus grandis)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MalvidsOGEM63042743
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT3G48160.21e-122DP-E2F-like 1
Publications ? help Back to Top
  1. Chandran D, et al.
    Atypical E2F transcriptional repressor DEL1 acts at the intersection of plant growth and immunity by controlling the hormone salicylic acid.
    Cell Host Microbe, 2014. 15(4): p. 506-13
    [PMID:24721578]
  2. Wang Z, et al.
    Del1 Knockout Mice Developed More Severe Osteoarthritis Associated with Increased Susceptibility of Chondrocytes to Apoptosis.
    PLoS ONE, 2016. 11(8): p. e0160684
    [PMID:27505251]
  3. Heyman J,Polyn S,Eekhout T,De Veylder L
    Tissue-Specific Control of the Endocycle by the Anaphase Promoting Complex/Cyclosome Inhibitors UVI4 and DEL1.
    Plant Physiol., 2017. 175(1): p. 303-313
    [PMID:28698355]