PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID FANhyb_icon00002702_a.1.g00001.1
Organism
Fragaria x ananassa
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Rosales; Rosaceae; Rosoideae; Potentilleae; Fragariinae; Fragaria
Family E2F/DP
Protein Properties Length: 252aa    MW: 27938.8 Da    PI: 9.9179
Description E2F/DP family protein
Gene Model
Gene Model ID Type Source Coding Sequence
FANhyb_icon00002702_a.1.g00001.1genomekazusaView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1E2F_TDP79.43.3e-2539119171
                           E2F_TDP   1 rkeksLrlltqkflkllekseegivtlnevakeLvse.....dvknkrRRiYDilNVLealnliek.....keknei 67 
                                       r+eksL lltq+f+kl+ +s+ + ++l+e+ak L+ +      +++k+RRiYDi+NVL+++nliek     ++k+++
  FANhyb_icon00002702_a.1.g00001.1  39 RREKSLALLTQNFVKLFVCSTVESISLDEAAKLLLGDvhnasIMRTKVRRIYDIANVLSSMNLIEKthtadTRKPAY 115
                                       689**************************************999***************************9***** PP

                           E2F_TDP  68 rwkg 71 
                                       +w g
  FANhyb_icon00002702_a.1.g00001.1 116 KWLG 119
                                       **87 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:1.10.10.106.9E-2435120IPR011991Winged helix-turn-helix DNA-binding domain
SMARTSM013721.2E-3139119IPR003316E2F/DP family, winged-helix DNA-binding domain
SuperFamilySSF467852.18E-1341120IPR011991Winged helix-turn-helix DNA-binding domain
PfamPF023192.0E-2041119IPR003316E2F/DP family, winged-helix DNA-binding domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0032876Biological Processnegative regulation of DNA endoreduplication
GO:0005634Cellular Componentnucleus
GO:0005667Cellular Componenttranscription factor complex
GO:0003677Molecular FunctionDNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 252 aa     Download sequence    Send to blast
CSQGSDDEEG DESGPATGSQ NENPGANPKS SANSKNDNRR EKSLALLTQN FVKLFVCSTV  60
ESISLDEAAK LLLGDVHNAS IMRTKVRRIY DIANVLSSMN LIEKTHTADT RKPAYKWLGL  120
RGKDAASSAS DESRKRAFGT DITNVSSKRG KVESSTTGKL EAQIQKQHES TVRQRESIVR  180
TVDRNNSEDS REGTKSYQFG PFAPVTIARA GNFNMKKVDW DNFSSTYRPQ YQNQANTGLF  240
RFNFTSGNQQ RP
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
4yo2_A5e-1722111138228Transcription factor E2F8
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtInhibitor of E2F-dependent activation of gene expression. Binds specifically the E2 recognition site without interacting with DP proteins and prevents transcription activation by E2F/DP heterodimers. Controls the timing of endocycle onset and inhibits endoreduplication. {ECO:0000269|PubMed:11786543, ECO:0000269|PubMed:11867638, ECO:0000269|PubMed:15649366, ECO:0000269|PubMed:18787127}.
Binding Motif ? help Back to Top
Motif ID Method Source Motif file
MP00397DAPTransfer from AT3G48160Download
Motif logo
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_004301283.11e-171PREDICTED: E2F transcription factor-like E2FE isoform X2
SwissprotQ8LSZ44e-68E2FE_ARATH; E2F transcription factor-like E2FE
TrEMBLA0A2P6P2731e-154A0A2P6P273_ROSCH; Putative transcription factor E2F-DP family
STRINGXP_004301283.11e-170(Fragaria vesca)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
FabidsOGEF36683366
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT3G48160.17e-71DP-E2F-like 1
Publications ? help Back to Top
  1. Chandran D, et al.
    Atypical E2F transcriptional repressor DEL1 acts at the intersection of plant growth and immunity by controlling the hormone salicylic acid.
    Cell Host Microbe, 2014. 15(4): p. 506-13
    [PMID:24721578]
  2. Wang Z, et al.
    Del1 Knockout Mice Developed More Severe Osteoarthritis Associated with Increased Susceptibility of Chondrocytes to Apoptosis.
    PLoS ONE, 2016. 11(8): p. e0160684
    [PMID:27505251]
  3. Heyman J,Polyn S,Eekhout T,De Veylder L
    Tissue-Specific Control of the Endocycle by the Anaphase Promoting Complex/Cyclosome Inhibitors UVI4 and DEL1.
    Plant Physiol., 2017. 175(1): p. 303-313
    [PMID:28698355]