PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

GRMZM2G017586_P01

Common Name

bHLH172, TIDP2894, ZEAMMB73_842128

Organism

Zea mays

Taxonomic ID

4577

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; Liliopsida; Petrosaviidae; commelinids; Poales; Poaceae; PACMAD clade; Panicoideae; Andropogonodae; Andropogoneae; Tripsacinae; Zea

Family

bHLH

Protein Properties

Length: 253aa MW: 27556.3 Da PI: 5.0455

Description

bHLH family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
GRMZM2G017586_P01	genome	MaizeSequence	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	HLH	30.9	5.1e-10	87	134	4	54
HHHHHHHHHHHHHHHHHHHHHCTSCCC...TTS-STCHHHHHHHHHHHHHH CS HLH 4 ahnerErrRRdriNsafeeLrellPkaskapskKlsKaeiLekAveYIksL 54 ++ rEr RR+++N++f eL + l + + K +Ka+iL A++ + +L GRMZM2G017586_P01 87 SKACRERMRRNKLNDRFLELGSALEPG---KPVKADKAAILSDATRMVIQL 134 6789********************9...99***********988777 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SuperFamily	SSF47459	7.46E-13	81	153	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
PROSITE profile	PS50888	11.998	83	134	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
CDD	cd00083	7.37E-8	86	139	No hit	No description
Pfam	PF00010	2.2E-7	87	134	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
Gene3D	G3DSA:4.10.280.10	1.1E-12	87	157	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
SMART	SM00353	4.8E-9	89	140	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0003677	Molecular Function	DNA binding
GO:0046983	Molecular Function	protein dimerization activity

Sequence ? help Back to Top
Protein Sequence Length: 253 aa Download sequence Send to blast
MSLPPGPADS GTGTGDDWFL DCGILDDLPA AACGAFPWDA SPSSSNPSVE VGSYVNANDA 60 FKEPNDVFKE PGSSKRLRSG SSDMPTSKAC RERMRRNKLN DRFLELGSAL EPGKPVKADK 120 AAILSDATRM VIQLRSESQQ LKETNGSLEE KIKELKAEKD ELRDEKQKLK LEKESLEHQM 180 KLMASAPAYM PHPTLMPAPF AQAPLAPFHA QGQAAGQKLM MPFVGYPGYP MWQFMPPSEV 240 DTSKDSEACP PVA

Expression -- UniGene ? help Back to Top
UniGene ID	E-value	Expressed in
Zm.118136	0.0	cell lignification\| endosperm\| meristem\| ovary\| pollen\| root\| shoot\| tassel

Expression -- Microarray ? help Back to Top
Source	ID
Expression Atlas	GRMZM2G017586

Expression -- Description ? help Back to Top
Source	Description
Uniprot	TISSUE SPECIFICITY: Widely expressed throughout development, mostly in vasculatures. {ECO:0000269\|PubMed:17028341}.

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription factor. Plays a role in resistance to amide-linked indole-3-acetic acid (IAA) conjugates such as IAA-Leu and IAA-Phe. May regulate gene expression in response to metal homeostasis changes. {ECO:0000269\|PubMed:17028341}.

Cis-element ? help Back to Top
Source	Link
PlantRegMap	GRMZM2G017586_P01

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	BT039742	0.0	BT039742.1 Zea mays full-length cDNA clone ZM_BFc0042O08 mRNA, complete cds.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_021320712.1	1e-166	transcription factor ILR3-like
Swissprot	Q9FH37	3e-69	ILR3_ARATH; Transcription factor ILR3
TrEMBL	B4FRK4	0.0	B4FRK4_MAIZE; BHLH transcription factor
STRING	GRMZM2G017586_P01	0.0	(Zea mays)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Monocots	OGMP2023	38	85
Representative plant	OGRP755	17	66

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT5G54680.1	9e-46	bHLH family protein

Link Out ? help Back to Top
Phytozome	GRMZM2G017586_P01
Entrez Gene	100284429

Publications ? help Back to Top
Alexandrov NN, et al. Insights into corn genes derived from large-scale cDNA sequencing. Plant Mol. Biol., 2009. 69(1-2): p. 179-94 [PMID:18937034] Li X,Zhang H,Ai Q,Liang G,Yu D Two bHLH Transcription Factors, bHLH34 and bHLH104, Regulate Iron Homeostasis in Arabidopsis thaliana. Plant Physiol., 2016. 170(4): p. 2478-93 [PMID:26921305] Aparicio F,Pallás V The coat protein of Alfalfa mosaic virus interacts and interferes with the transcriptional activity of the bHLH transcription factor ILR3 promoting salicylic acid-dependent defence signalling response. Mol. Plant Pathol., 2017. 18(2): p. 173-186 [PMID:26929142] Liang G,Zhang H,Li X,Ai Q,Yu D bHLH transcription factor bHLH115 regulates iron homeostasis in Arabidopsis thaliana. J. Exp. Bot., 2017. 68(7): p. 1743-1755 [PMID:28369511] Ezer D, et al. The G-Box Transcriptional Regulatory Code in Arabidopsis. Plant Physiol., 2017. 175(2): p. 628-640 [PMID:28864470] Li B, et al. Network-Guided Discovery of Extensive Epistasis between Transcription Factors Involved in Aliphatic Glucosinolate Biosynthesis. Plant Cell, 2018. 30(1): p. 178-195 [PMID:29317470] Min JH, et al. Arabidopsis Basic Helix-Loop-Helix 34 (bHLH34) Is Involved in Glucose Signaling through Binding to a GAGA Cis-Element. Front Plant Sci, 2017. 8: p. 2100 [PMID:29321786] Samira R, et al. The bHLH transcription factor ILR3 modulates multiple stress responses in Arabidopsis. Plant Mol. Biol., 2018. 97(4-5): p. 297-309 [PMID:29882068]