PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID GRMZM2G050939_P05
Common NameTFIIIA
Organism
Zea mays
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; Liliopsida; Petrosaviidae; commelinids; Poales; Poaceae; PACMAD clade; Panicoideae; Andropogonodae; Andropogoneae; Tripsacinae; Zea
Family C2H2
Protein Properties Length: 226aa    MW: 26137.9 Da    PI: 8.6753
Description C2H2 family protein
Gene Model
Gene Model ID Type Source Coding Sequence
GRMZM2G050939_P05genomeMaizeSequenceView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1zf-C2H220.41.3e-062145123
                       EEET..TTTEEESSHHHHHHHHHHT CS
            zf-C2H2  1 ykCp..dCgksFsrksnLkrHirtH 23
                       + Cp  +Cgk F+  s Lk+H  +H
  GRMZM2G050939_P05 21 FICPkvNCGKAFKYASKLKKHEESH 45
                       78*******************9988 PP
2zf-C2H216.81.9e-05112136223
                        EET..TTTEEESSHHHHHHHHHH.T CS
            zf-C2H2   2 kCp..dCgksFsrksnLkrHirt.H 23 
                        kC+  dC+ sFs ksnL +H +  H
  GRMZM2G050939_P05 112 KCHieDCKCSFSKKSNLDKHVKAvH 136
                        7*******************99877 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:3.30.160.601.2E-61745IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
SuperFamilySSF576678.87E-51847No hitNo description
SMARTSM003550.00972145IPR015880Zinc finger, C2H2-like
PROSITE profilePS5015711.3852150IPR007087Zinc finger, C2H2
PROSITE patternPS0002802345IPR007087Zinc finger, C2H2
SMARTSM00355195378IPR015880Zinc finger, C2H2-like
PROSITE patternPS0002805578IPR007087Zinc finger, C2H2
SMARTSM003551781102IPR015880Zinc finger, C2H2-like
SuperFamilySSF576673.27E-792153No hitNo description
PROSITE profilePS5015711.843111141IPR007087Zinc finger, C2H2
SMARTSM003550.069111136IPR015880Zinc finger, C2H2-like
Gene3DG3DSA:3.30.160.601.4E-4111136IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
PROSITE patternPS000280113136IPR007087Zinc finger, C2H2
Gene3DG3DSA:3.30.160.602.5E-6137165IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
PROSITE profilePS501579.286142171IPR007087Zinc finger, C2H2
SMARTSM003551.8142168IPR015880Zinc finger, C2H2-like
PROSITE patternPS000280144168IPR007087Zinc finger, C2H2
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0005730Cellular Componentnucleolus
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
GO:0008097Molecular Function5S rRNA binding
GO:0046872Molecular Functionmetal ion binding
GO:0080084Molecular Function5S rDNA binding
Plant Ontology ? help Back to Top
PO Term PO Category PO Description
PO:0000037anatomyshoot apex
PO:0006310anatomytassel floret
PO:0006339anatomyjuvenile vascular leaf
PO:0006340anatomyadult vascular leaf
PO:0006341anatomyprimary shoot system
PO:0006354anatomyear floret
PO:0006505anatomycentral spike of ear inflorescence
PO:0008018anatomytransition vascular leaf
PO:0009001anatomyfruit
PO:0009009anatomyplant embryo
PO:0009025anatomyvascular leaf
PO:0009054anatomyinflorescence bract
PO:0009066anatomyanther
PO:0009074anatomystyle
PO:0009084anatomypericarp
PO:0009089anatomyendosperm
PO:0020040anatomyleaf base
PO:0020104anatomyleaf sheath
PO:0020126anatomytassel inflorescence
PO:0020127anatomyprimary root
PO:0020136anatomyear inflorescence
PO:0020142anatomystem internode
PO:0020148anatomyshoot apical meristem
PO:0025142anatomyleaf tip
PO:0025287anatomyseedling coleoptile
PO:0001007developmental stagepollen development stage
PO:0001009developmental stageD pollen mother cell meiosis stage
PO:0001052developmental stagevascular leaf expansion stage
PO:0001053developmental stagevascular leaf post-expansion stage
PO:0001083developmental stageinflorescence development stage
PO:0001094developmental stageplant embryo coleoptilar stage
PO:0001095developmental stageplant embryo true leaf formation stage
PO:0001180developmental stageplant proembryo stage
PO:0007001developmental stageearly whole plant fruit ripening stage
PO:0007003developmental stageIL.03 full inflorescence length reached stage
PO:0007006developmental stageIL.00 inflorescence just visible stage
PO:0007015developmental stageradicle emergence stage
PO:0007016developmental stagewhole plant flowering stage
PO:0007022developmental stageseed imbibition stage
PO:0007026developmental stageFL.00 first flower(s) open stage
PO:0007031developmental stagemid whole plant fruit ripening stage
PO:0007032developmental stagewhole plant fruit formation stage up to 10%
PO:0007045developmental stagecoleoptile emergence stage
PO:0007063developmental stageLP.07 seven leaves visible stage
PO:0007065developmental stageLP.05 five leaves visible stage
PO:0007072developmental stageLP.18 eighteen leaves visible stage
PO:0007094developmental stageLP.01 one leaf visible stage
PO:0007101developmental stageLP.09 nine leaves visible stage
PO:0007104developmental stageLP.15 fifteen leaves visible stage
PO:0007106developmental stageLP.03 three leaves visible stage
PO:0007112developmental stage1 main shoot growth stage
PO:0007116developmental stageLP.11 eleven leaves visible stage
PO:0007123developmental stageLP.06 six leaves visible stage
PO:0007633developmental stageendosperm development stage
PO:0021004developmental stageinflorescence initiation stage
Sequence ? help Back to Top
Protein Sequence    Length: 226 aa     Download sequence    Send to blast
MQRHVQEIHK DVSPCESKKE FICPKVNCGK AFKYASKLKK HEESHVQLEY TEVMCCEPGC  60
MKFFSNMECL KAHNQSCHQY VQCDICGTKQ LKKNFQRHHR MHEGSCVTER VKCHIEDCKC  120
SFSKKSNLDK HVKAVHEQRR PFVCQFSGCG KRFSYKHVRD NHEKSSAHVH TEGDFVEADE  180
QRPRSVGGCK RKPVSVESLM RKRVAAPDDG PAHADATEYL RWLLSV
Expression -- UniGene ? help Back to Top
UniGene ID E-value Expressed in
Zm.304080.0meristem| shoot
Expression -- Microarray ? help Back to Top
Source ID
Expression AtlasGRMZM2G050939
Expression -- Description ? help Back to Top
Source Description
UniprotDEVELOPMENTAL STAGE: Both isoforms 1 and 2 transcripts are expressed in seedlings and both TFIIIA and TFIIIA-C are present at similar ratios in 10-day-old seedlings (at protein level). In correlation with the reorganization of 5S rDNA chromatin to a mature state, full-length isoform 1 protein TFIIIA with transcriptional activity accumulates and permits de novo transcription of 5S rRNA. Isoforms 1 and 2 transcripts accumulate in various tissues of the reproductive phase, including flowers and siliques, but only isoform 2 is present in mature seeds. In flowers, both TFIIIA and TFIIIA-C are present at similar ratios (at protein level). Very low amounts of TFIIIA are found in extracts from fresh siliques compared to TFIIIA-C. The amount of full-length TFIIIA protein progressively increases from fresh siliques to seeds concomitant with lower proportions of the shorter TFIIIA-C protein (at protein level) thus leading to 5S rRNA accumulation in the seed. {ECO:0000269|PubMed:22353599}.
UniprotTISSUE SPECIFICITY: Expressed in seedlings, flowers, siliques and seeds. {ECO:0000269|PubMed:22353599}.
Functional Description ? help Back to Top
Source Description
UniProtEssential protein (PubMed:22353599). Isoform 1 is a transcription activator the binds both 5S rDNA and 5S rRNA and stimulates the transcription of 5S rRNA gene (PubMed:12711688, PubMed:22353599). Isoform 1 regulates 5S rRNA levels during development (PubMed:22353599). {ECO:0000269|PubMed:12711688, ECO:0000269|PubMed:22353599}.
Binding Motif ? help Back to Top
Motif ID Method Source Motif file
MP00229DAPTransfer from AT1G72050Download
Motif logo
Cis-element ? help Back to Top
SourceLink
PlantRegMapGRMZM2G050939_P05
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieveRetrieve
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankBT0628020.0BT062802.1 Zea mays full-length cDNA clone ZM_BFb0348B01 mRNA, complete cds.
GenBankBT0668270.0BT066827.1 Zea mays full-length cDNA clone ZM_BFb0075I12 mRNA, complete cds.
GenBankBT0677630.0BT067763.1 Zea mays full-length cDNA clone ZM_BFc0152L06 mRNA, complete cds.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqNP_001349024.11e-167uncharacterized LOC100383605 isoform 2
RefseqXP_008648128.11e-165uncharacterized LOC100383605 isoform X1
SwissprotQ84MZ42e-72TF3A_ARATH; Transcription factor IIIA
TrEMBLC0P3D31e-166C0P3D3_MAIZE; Transcription factor IIIA
STRINGGRMZM2G050939_P021e-164(Zea mays)
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT1G72050.11e-74transcription factor IIIA
Publications ? help Back to Top
  1. Fu Y, et al.
    Alternative splicing of anciently exonized 5S rRNA regulates plant transcription factor TFIIIA.
    Genome Res., 2009. 19(5): p. 913-21
    [PMID:19211543]