PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID GSMUA_Achr2P20420_001
Organism
Musa acuminata
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; Liliopsida; Petrosaviidae; commelinids; Zingiberales; Musaceae; Musa
Family E2F/DP
Protein Properties Length: 418aa    MW: 46748.7 Da    PI: 4.733
Description E2F/DP family protein
Gene Model
Gene Model ID Type Source Coding Sequence
GSMUA_Achr2P20420_001genomeCIRADView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1E2F_TDP84.67.6e-2787152171
                E2F_TDP   1 rkeksLrlltqkflkllekseegivtlnevakeLvsedvknkrRRiYDilNVLealnliekkekneirwkg 71 
                            r+++sL+llt+kf++ll+++++gi++ln++a+ L   +v  ++RRiYDi+NVLe+++liekk kn+irwkg
  GSMUA_Achr2P20420_001  87 RYDSSLGLLTKKFINLLKHTRDGILDLNKAAEIL---KV--QKRRIYDITNVLEGIGLIEKKLKNRIRWKG 152
                            6899******************************...88..****************************98 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:1.10.10.102.3E-2885153IPR011991Winged helix-turn-helix DNA-binding domain
SMARTSM013729.6E-3487152IPR003316E2F/DP family, winged-helix DNA-binding domain
SuperFamilySSF467853.1E-1787150IPR011991Winged helix-turn-helix DNA-binding domain
PfamPF023196.5E-2489152IPR003316E2F/DP family, winged-helix DNA-binding domain
SuperFamilySSF1440741.44E-33166272No hitNo description
CDDcd146603.09E-47166272No hitNo description
PfamPF164211.1E-32168270IPR032198E2F transcription factor, CC-MB domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0005667Cellular Componenttranscription factor complex
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 418 aa     Download sequence    Send to blast
MSFIYIHFLK QKSVQEDNEV VEISEWTTSP GCAVGFTSPL LTPVSEKGRK TYSKSKVAKH  60
NKSGGQTPVS NAGSPTGDNL TPVGSCRYDS SLGLLTKKFI NLLKHTRDGI LDLNKAAEIL  120
KVQKRRIYDI TNVLEGIGLI EKKLKNRIRW KGIDDLGSVE VDGDASKLQA ETESLTTKER  180
RLDELISQMR EKLRELTEDE SNQKWLFITE DDIKGLPCFQ NETLIAIKAP HGTTLEVPDP  240
DEASRRTKSY LKRYRIVLRS TMGPIDVYLV SQFEEKFEEM SGVEIPPKLL PTSNSDSVEY  300
SMVPIVTEES RGNEMELDIQ QSERIWSDVN SSHDFGGGMM KIVPSDIDTE ADYWLLSDAG  360
VSITEMWKTA PEIEWDAMGR FGTESTDDFI TDGATTPRPQ TPPSGVVEVP SDATSSRR
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1cf7_A4e-2382153274PROTEIN (TRANSCRIPTION FACTOR E2F-4)
Search in ModeBase
Nucleic Localization Signal ? help Back to Top
NLS
No. Start End Sequence
1119125LKVQKRR
Functional Description ? help Back to Top
Source Description
UniProtTranscription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The binding of retinoblastoma-related proteins represses transactivation. Involved in the control of cell-cycle progression from G1 to S phase and from G2 to M phase. Stimulates cell proliferation and delays differentiation. Represses cell enlargement and endoreduplication in auxin-free conditions. {ECO:0000269|PubMed:11669580, ECO:0000269|PubMed:11786543, ECO:0000269|PubMed:11862494, ECO:0000269|PubMed:11891240, ECO:0000269|PubMed:12913157, ECO:0000269|PubMed:16055635, ECO:0000269|PubMed:16514015}.
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Up-regulated by light and by auxin. May be up-regulated by E2FA. {ECO:0000269|PubMed:16055635, ECO:0000269|PubMed:16514015, ECO:0000269|PubMed:18424613}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_009390043.10.0PREDICTED: transcription factor E2FB
SwissprotQ9FV711e-125E2FB_ARATH; Transcription factor E2FB
TrEMBLM0S9N30.0M0S9N3_MUSAM; Uncharacterized protein
STRINGGSMUA_Achr2P20420_0010.0(Musa acuminata)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MonocotsOGMP62537148
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT5G22220.31e-127E2F transcription factor 1
Publications ? help Back to Top
  1. Heyndrickx KS,Vandepoele K
    Systematic identification of functional plant modules through the integration of complementary data sources.
    Plant Physiol., 2012. 159(3): p. 884-901
    [PMID:22589469]
  2. Wu M,Liu L,Hijazi H,Chan C
    A multi-layer inference approach to reconstruct condition-specific genes and their regulation.
    Bioinformatics, 2013. 29(12): p. 1541-52
    [PMID:23610368]
  3. Kobayashi K, et al.
    Transcriptional repression by MYB3R proteins regulates plant organ growth.
    EMBO J., 2015. 34(15): p. 1992-2007
    [PMID:26069325]