PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

GSMUA_Achr3P00370_001

Organism

Musa acuminata

Taxonomic ID

4641

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; Liliopsida; Petrosaviidae; commelinids; Zingiberales; Musaceae; Musa

Family

bHLH

Protein Properties

Length: 440aa MW: 47539.5 Da PI: 7.9993

Description

bHLH family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
GSMUA_Achr3P00370_001	genome	CIRAD	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	HLH	40	7e-13	300	344	5	54
HHHHHHHHHHHHHHHHHHHHCTSCCC...TTS-STCHHHHHHHHHHHHHH CS HLH 5 hnerErrRRdriNsafeeLrellPkaskapskKlsKaeiLekAveYIksL 54 h e+Er+RR+++N++f Lr+++P+ K++Ka+ L A+ YI++L GSMUA_Achr3P00370_001 300 HVEAERQRREKLNQRFYALRSVVPNV-----SKMDKASLLADAIAYINEL 344 899********************6.....5*************998 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Pfam	PF14215	6.0E-40	50	202	IPR025610	Transcription factor MYC/MYB N-terminal
SuperFamily	SSF47459	5.76E-16	294	350	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
PROSITE profile	PS50888	16.463	295	344	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
Gene3D	G3DSA:4.10.280.10	8.5E-16	300	349	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
Pfam	PF00010	2.3E-10	300	344	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
CDD	cd00083	7.81E-14	300	347	No hit	No description
SMART	SM00353	9.6E-14	301	350	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0046983	Molecular Function	protein dimerization activity

Sequence ? help Back to Top
Protein Sequence Length: 440 aa Download sequence Send to blast
MESFLSPFPV PRWPPPPLAH SASSSFSSSS SSSRSTVTSF APPSLNPETL QQRLNALIEG 60 GPENWTYAIF WQSSPAGGAA ALSWGDGYYR SCEEDKRKPA GVGASSTAEQ EHRKRWFFLV 120 SMTQTFAPGA GLPGQVLLSG ETVWVAGEDR LAAAPCERAQ QAWAFGLRTM ACVPMGSGVV 180 ELGSTQDIFH NSEILSKVRL LFGRGRGGGG HATGSLPPPP EQGLTNKSTS RGSDDGGFLP 240 SSTAVAATAP KPEGGGLDSD HSDLEGSARE ATSSATLERE KRPKKRGRKP ANGREVPIDH 300 VEAERQRREK LNQRFYALRS VVPNVSKMDK ASLLADAIAY INELHTKWTT SETGTSGEGE 360 GEVEVEVKLL GREAMIRVQC ERRAHPAARL MVALRELELE VYYANVTVVK ELMIQQATVK 420 MGSRIYNQEQ LTAALFARVA

Sequence ? help Back to Top

Protein Sequence Length: 440 aa Download sequence Send to blast

MESFLSPFPV PRWPPPPLAH SASSSFSSSS SSSRSTVTSF APPSLNPETL QQRLNALIEG  60
GPENWTYAIF WQSSPAGGAA ALSWGDGYYR SCEEDKRKPA GVGASSTAEQ EHRKRWFFLV  120
SMTQTFAPGA GLPGQVLLSG ETVWVAGEDR LAAAPCERAQ QAWAFGLRTM ACVPMGSGVV  180
ELGSTQDIFH NSEILSKVRL LFGRGRGGGG HATGSLPPPP EQGLTNKSTS RGSDDGGFLP  240
SSTAVAATAP KPEGGGLDSD HSDLEGSARE ATSSATLERE KRPKKRGRKP ANGREVPIDH  300
VEAERQRREK LNQRFYALRS VVPNVSKMDK ASLLADAIAY INELHTKWTT SETGTSGEGE  360
GEVEVEVKLL GREAMIRVQC ERRAHPAARL MVALRELELE VYYANVTVVK ELMIQQATVK  420
MGSRIYNQEQ LTAALFARVA

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
4rqw_A	7e-44	43	202	2	192	Transcription factor MYC3
4rqw_B	7e-44	43	202	2	192	Transcription factor MYC3
4rs9_A	7e-44	43	202	2	192	Transcription factor MYC3
4yz6_A	7e-44	43	202	2	192	Transcription factor MYC3
Search in ModeBase

Nucleic Localization Signal ? help Back to Top

No.	Start	End	Sequence
1	280	288	KRPKKRGRK

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription factor involved in jasmonic acid (JA) gene regulation. With MYC2 and MYC3, controls additively subsets of JA-dependent responses. Can form complexes with all known glucosinolate-related MYBs to regulate glucosinolate biosynthesis. Binds to the G-box (5'-CACGTG-3') of promoters. Activates multiple TIFY/JAZ promoters. {ECO:0000269\|PubMed:21321051, ECO:0000269\|PubMed:21335373, ECO:0000269\|PubMed:23943862}.

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: By UV treatment. Not induced by jasmonic acid. {ECO:0000269\|PubMed:12679534, ECO:0000269\|PubMed:21335373}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_009391048.2	0.0	PREDICTED: transcription factor MYC2-like, partial
Swissprot	O49687	1e-119	MYC4_ARATH; Transcription factor MYC4
TrEMBL	M0SAK5	0.0	M0SAK5_MUSAM; Uncharacterized protein
STRING	GSMUA_Achr3P00370_001	0.0	(Musa acuminata)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Monocots	OGMP4452	31	57

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT5G46830.1	1e-72	NACL-inducible gene 1

Publications ? help Back to Top
Ding Y, et al. Four distinct types of dehydration stress memory genes in Arabidopsis thaliana. BMC Plant Biol., 2013. 13: p. 229 [PMID:24377444] Chico JM, et al. Repression of Jasmonate-Dependent Defenses by Shade Involves Differential Regulation of Protein Stability of MYC Transcription Factors and Their JAZ Repressors in Arabidopsis. Plant Cell, 2014. 26(5): p. 1967-1980 [PMID:24824488] Gasperini D, et al. Multilayered Organization of Jasmonate Signalling in the Regulation of Root Growth. PLoS Genet., 2015. 11(6): p. e1005300 [PMID:26070206] Qi T, et al. Regulation of Jasmonate-Induced Leaf Senescence by Antagonism between bHLH Subgroup IIIe and IIId Factors in Arabidopsis. Plant Cell, 2015. 27(6): p. 1634-49 [PMID:26071420] de Torres Zabala M, et al. Novel JAZ co-operativity and unexpected JA dynamics underpin Arabidopsis defence responses to Pseudomonas syringae infection. New Phytol., 2016. 209(3): p. 1120-34 [PMID:26428397] Yu J, et al. JAZ7 negatively regulates dark-induced leaf senescence in Arabidopsis. J. Exp. Bot., 2016. 67(3): p. 751-62 [PMID:26547795] Chen X,Huang H,Qi T,Liu B,Song S New perspective of the bHLH-MYB complex in jasmonate-regulated plant fertility in arabidopsis. Plant Signal Behav, 2016. 11(2): p. e1135280 [PMID:26829586] Schmiesing A,Emonet A,Gouhier-Darimont C,Reymond P Arabidopsis MYC Transcription Factors Are the Target of Hormonal Salicylic Acid/Jasmonic Acid Cross Talk in Response to Pieris brassicae Egg Extract. Plant Physiol., 2016. 170(4): p. 2432-43 [PMID:26884488] Thatcher LF, et al. Characterization of a JAZ7 activation-tagged Arabidopsis mutant with increased susceptibility to the fungal pathogen Fusarium oxysporum. J. Exp. Bot., 2016. 67(8): p. 2367-86 [PMID:26896849] Gao C, et al. MYC2, MYC3, and MYC4 function redundantly in seed storage protein accumulation in Arabidopsis. Plant Physiol. Biochem., 2016. 108: p. 63-70 [PMID:27415132] Gimenez-Ibanez S, et al. JAZ2 controls stomata dynamics during bacterial invasion. New Phytol., 2017. 213(3): p. 1378-1392 [PMID:28005270] Lian TF,Xu YP,Li LF,Su XD Crystal Structure of Tetrameric Arabidopsis MYC2 Reveals the Mechanism of Enhanced Interaction with DNA. Cell Rep, 2017. 19(7): p. 1334-1342 [PMID:28514654] Wang H, et al. The bHLH Transcription Factors MYC2, MYC3, and MYC4 Are Required for Jasmonate-Mediated Inhibition of Flowering in Arabidopsis. Mol Plant, 2017. 10(11): p. 1461-1464 [PMID:28827172] Song S, et al. MYC5 is Involved in Jasmonate-Regulated Plant Growth, Leaf Senescence and Defense Responses. Plant Cell Physiol., 2017. 58(10): p. 1752-1763 [PMID:29017003] Li B, et al. Network-Guided Discovery of Extensive Epistasis between Transcription Factors Involved in Aliphatic Glucosinolate Biosynthesis. Plant Cell, 2018. 30(1): p. 178-195 [PMID:29317470] Han X, et al. Jasmonate Negatively Regulates Stomatal Development in Arabidopsis Cotyledons. Plant Physiol., 2018. 176(4): p. 2871-2885 [PMID:29496884]