PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

GSMUA_Achr6P18220_001

Organism

Musa acuminata

Taxonomic ID

4641

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; Liliopsida; Petrosaviidae; commelinids; Zingiberales; Musaceae; Musa

Family

E2F/DP

Protein Properties

Length: 409aa MW: 45422.4 Da PI: 4.8746

Description

E2F/DP family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
GSMUA_Achr6P18220_001	genome	CIRAD	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	E2F_TDP	82.7	3e-26	78	143	1	71
E2F_TDP 1 rkeksLrlltqkflkllekseegivtlnevakeLvsedvknkrRRiYDilNVLealnliekkekneirwkg 71 r+++sL+llt++f++ll+++++gi++ln++a++L +v ++RRiYDi+NVLe+++liekk kn+i wkg GSMUA_Achr6P18220_001 78 RYDSSLGLLTKRFISLLKQAQDGILDLNNAAETL---EV--QKRRIYDITNVLEGIGLIEKKLKNKICWKG 143 6899****************************...99..**************************98 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Gene3D	G3DSA:1.10.10.10	3.3E-28	76	145	IPR011991	Winged helix-turn-helix DNA-binding domain
SMART	SM01372	1.2E-33	78	143	IPR003316	E2F/DP family, winged-helix DNA-binding domain
SuperFamily	SSF46785	9.07E-17	78	141	IPR011991	Winged helix-turn-helix DNA-binding domain
Pfam	PF02319	1.1E-23	80	143	IPR003316	E2F/DP family, winged-helix DNA-binding domain
CDD	cd14660	1.35E-46	154	260	No hit	No description
SuperFamily	SSF144074	2.28E-32	155	260	No hit	No description
Pfam	PF16421	4.8E-32	159	258	IPR032198	E2F transcription factor, CC-MB domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0005667	Cellular Component	transcription factor complex
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 409 aa Download sequence Send to blast
MSIGYKYCLF FKLRLYELKT SPGYAGANNA LLTPVTGKGG KTNGRSKAAK YNKSGPQTPM 60 SNVGSASGNV LTPVGTCRYD SSLGLLTKRF ISLLKQAQDG ILDLNNAAET LEVQKRRIYD 120 ITNVLEGIGL IEKKLKNKIC WKGLDNARPG EVDDDLSVLQ AEIKKLALQE HGLDDRISKI 180 QERLRVFSED ERNQRWLYVT EDDIKGLPCF QNETLIAIKA PHGTTLEVPD PDEAGEYPQR 240 RYRIVLRSTM GPIDVYLVSQ FEEKFEEMNS IETPLRLNPM ADSQTVENSM LAIATEESRR 300 KETEFKDQDC QRACPDISSS QDAGGGMMKI VPCDVDTDAD YWLLSESGVS ITDMWKTSPE 360 VQWDRICAFS TDDFVTSGAG TPRPPAPTSG VIDPLTQTLL GNKCRADNL

Sequence ? help Back to Top

Protein Sequence Length: 409 aa Download sequence Send to blast

MSIGYKYCLF FKLRLYELKT SPGYAGANNA LLTPVTGKGG KTNGRSKAAK YNKSGPQTPM  60
SNVGSASGNV LTPVGTCRYD SSLGLLTKRF ISLLKQAQDG ILDLNNAAET LEVQKRRIYD  120
ITNVLEGIGL IEKKLKNKIC WKGLDNARPG EVDDDLSVLQ AEIKKLALQE HGLDDRISKI  180
QERLRVFSED ERNQRWLYVT EDDIKGLPCF QNETLIAIKA PHGTTLEVPD PDEAGEYPQR  240
RYRIVLRSTM GPIDVYLVSQ FEEKFEEMNS IETPLRLNPM ADSQTVENSM LAIATEESRR  300
KETEFKDQDC QRACPDISSS QDAGGGMMKI VPCDVDTDAD YWLLSESGVS ITDMWKTSPE  360
VQWDRICAFS TDDFVTSGAG TPRPPAPTSG VIDPLTQTLL GNKCRADNL

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
1cf7_A	1e-24	73	144	1	74	PROTEIN (TRANSCRIPTION FACTOR E2F-4)
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Functional Description ? help Back to Top
Source	Description
UniProt	Transcription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The binding of retinoblastoma-related proteins represses transactivation. Involved in the control of cell-cycle progression from G1 to S phase and from G2 to M phase. Stimulates cell proliferation and delays differentiation. Represses cell enlargement and endoreduplication in auxin-free conditions. {ECO:0000269\|PubMed:11669580, ECO:0000269\|PubMed:11786543, ECO:0000269\|PubMed:11862494, ECO:0000269\|PubMed:11891240, ECO:0000269\|PubMed:12913157, ECO:0000269\|PubMed:16055635, ECO:0000269\|PubMed:16514015}.

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Up-regulated by light and by auxin. May be up-regulated by E2FA. {ECO:0000269\|PubMed:16055635, ECO:0000269\|PubMed:16514015, ECO:0000269\|PubMed:18424613}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_009404915.1	0.0	PREDICTED: transcription factor E2FB-like isoform X1
Swissprot	Q9FV71	1e-129	E2FB_ARATH; Transcription factor E2FB
TrEMBL	M0T820	0.0	M0T820_MUSAM; Uncharacterized protein
STRING	GSMUA_Achr6P18220_001	0.0	(Musa acuminata)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Monocots	OGMP625	37	148

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT5G22220.3	1e-132	E2F transcription factor 1

Publications ? help Back to Top
Heyndrickx KS,Vandepoele K Systematic identification of functional plant modules through the integration of complementary data sources. Plant Physiol., 2012. 159(3): p. 884-901 [PMID:22589469] Wu M,Liu L,Hijazi H,Chan C A multi-layer inference approach to reconstruct condition-specific genes and their regulation. Bioinformatics, 2013. 29(12): p. 1541-52 [PMID:23610368] Kobayashi K, et al. Transcriptional repression by MYB3R proteins regulates plant organ growth. EMBO J., 2015. 34(15): p. 1992-2007 [PMID:26069325]