PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID GSMUA_Achr7P02220_001
Organism
Musa acuminata
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; Liliopsida; Petrosaviidae; commelinids; Zingiberales; Musaceae; Musa
Family E2F/DP
Protein Properties Length: 388aa    MW: 43193.9 Da    PI: 8.3662
Description E2F/DP family protein
Gene Model
Gene Model ID Type Source Coding Sequence
GSMUA_Achr7P02220_001genomeCIRADView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1E2F_TDP702.8e-222085171
                E2F_TDP  1 rkeksLrlltqkflkllekseegivtlnevakeLvsedvknkrRRiYDilNVLealnliekkekneirwkg 71
                           rk+ksL++l+++f++l+ +   + v l+ +a++L    v  +rRRiYDi+NV+e+++++++k+kn+++w+g
  GSMUA_Achr7P02220_001 20 RKQKSLGVLCSNFVSLYDRDGVELVGLDYAARQL---GV--ERRRIYDIVNVMESVGVLARKAKNKYSWIG 85
                           79*****************999************...**..****************************98 PP
2E2F_TDP77.71.1e-24164243171
                E2F_TDP   1 rkeksLrlltqkflkllekseegivtlnevakeLvse.....dvknkrRRiYDilNVLealnliek....kekneirwkg 71 
                            rkeksL+llt++f+kl+ +s+ ++++l+e+a+ L+ +     ++++k+RR+YDi+NVL+++ liek     +k+++rw g
  GSMUA_Achr7P02220_001 164 RKEKSLGLLTRNFVKLFLTSDVDTISLDEAARLLLGDisdlsNMRTKVRRLYDIANVLSSMSLIEKiqveARKPAFRWLG 243
                            79*******************************************************************99*******87 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:1.10.10.101.9E-251586IPR011991Winged helix-turn-helix DNA-binding domain
SuperFamilySSF467859.07E-152084IPR011991Winged helix-turn-helix DNA-binding domain
SMARTSM013721.4E-252085IPR003316E2F/DP family, winged-helix DNA-binding domain
PfamPF023196.9E-202185IPR003316E2F/DP family, winged-helix DNA-binding domain
Gene3DG3DSA:1.10.10.102.0E-22160244IPR011991Winged helix-turn-helix DNA-binding domain
SMARTSM013721.4E-29164243IPR003316E2F/DP family, winged-helix DNA-binding domain
PfamPF023191.7E-19165243IPR003316E2F/DP family, winged-helix DNA-binding domain
SuperFamilySSF467851.29E-12166244IPR011991Winged helix-turn-helix DNA-binding domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0032876Biological Processnegative regulation of DNA endoreduplication
GO:0005634Cellular Componentnucleus
GO:0005667Cellular Componenttranscription factor complex
GO:0003677Molecular FunctionDNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 388 aa     Download sequence    Send to blast
MSSSPSQFLD SGSKHHSYCR KQKSLGVLCS NFVSLYDRDG VELVGLDYAA RQLGVERRRI  60
YDIVNVMESV GVLARKAKNK YSWIGFSGIP KALKELKEEA LRAISGSDGP CEKVGLMKEV  120
LEDEDDDSEG QNHDDGDEKF SKMDNASSSS GNHISKARSA TDNRKEKSLG LLTRNFVKLF  180
LTSDVDTISL DEAARLLLGD ISDLSNMRTK VRRLYDIANV LSSMSLIEKI QVEARKPAFR  240
WLGTEGKPKT DTGGTFAPPP IVKPLNKRAF GNEITNVDMK RSRLCCTVSK KPGKAQMRSD  300
DLKECNLTAQ KQLITKSGYV FGPFCPAGMT KVDGDVEGKG ERSAQDWESL ACSLRPQYHN  360
QALNELFTHY MEAWKSWYSE LAQGSYNL
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
4yo2_A1e-34202374232Transcription factor E2F8
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtInhibitor of E2F-dependent activation of gene expression. Binds specifically the E2 recognition site without interacting with DP proteins and prevents transcription activation by E2F/DP heterodimers. Controls the timing of endocycle onset and inhibits endoreduplication. {ECO:0000269|PubMed:11786543, ECO:0000269|PubMed:11867638, ECO:0000269|PubMed:15649366, ECO:0000269|PubMed:18787127}.
Binding Motif ? help Back to Top
Motif ID Method Source Motif file
MP00397DAPTransfer from AT3G48160Download
Motif logo
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieveRetrieve
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_009408421.10.0PREDICTED: E2F transcription factor-like E2FE isoform X2
SwissprotQ8LSZ41e-105E2FE_ARATH; E2F transcription factor-like E2FE
TrEMBLM0TE120.0M0TE12_MUSAM; Uncharacterized protein
STRINGGSMUA_Achr7P02220_0010.0(Musa acuminata)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MonocotsOGMP31853884
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT3G48160.21e-108DP-E2F-like 1
Publications ? help Back to Top
  1. Chandran D, et al.
    Atypical E2F transcriptional repressor DEL1 acts at the intersection of plant growth and immunity by controlling the hormone salicylic acid.
    Cell Host Microbe, 2014. 15(4): p. 506-13
    [PMID:24721578]
  2. Wang Z, et al.
    Del1 Knockout Mice Developed More Severe Osteoarthritis Associated with Increased Susceptibility of Chondrocytes to Apoptosis.
    PLoS ONE, 2016. 11(8): p. e0160684
    [PMID:27505251]
  3. Heyman J,Polyn S,Eekhout T,De Veylder L
    Tissue-Specific Control of the Endocycle by the Anaphase Promoting Complex/Cyclosome Inhibitors UVI4 and DEL1.
    Plant Physiol., 2017. 175(1): p. 303-313
    [PMID:28698355]