PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID GSVIVT01009890001
Common NameLOC100247139, VIT_18s0001g14110
Organism
Vitis vinifera
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; rosids incertae sedis; Vitales; Vitaceae; Vitis
Family E2F/DP
Protein Properties Length: 437aa    MW: 48737.2 Da    PI: 4.7466
Description E2F/DP family protein
Gene Model
Gene Model ID Type Source Coding Sequence
GSVIVT01009890001genomeGenoscopeView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1E2F_TDP84.49.1e-27148213171
            E2F_TDP   1 rkeksLrlltqkflkllekseegivtlnevakeLvsedvknkrRRiYDilNVLealnliekkekneirwkg 71 
                        r+++sL+llt+kf++l++++++g+++ln  a+ L   +v  ++RRiYDi+NVLe+++liek++kn+i+wkg
  GSVIVT01009890001 148 RYDSSLGLLTKKFISLIQEAKDGTLDLNRTADVL---EV--QKRRIYDITNVLEGIGLIEKTSKNHISWKG 213
                        6899******************************...99..****************************98 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:1.10.10.105.4E-28146214IPR011991Winged helix-turn-helix DNA-binding domain
SuperFamilySSF467852.45E-17148211IPR011991Winged helix-turn-helix DNA-binding domain
SMARTSM013723.4E-35148213IPR003316E2F/DP family, winged-helix DNA-binding domain
PfamPF023195.5E-25150213IPR003316E2F/DP family, winged-helix DNA-binding domain
CDDcd146604.66E-37224328No hitNo description
SuperFamilySSF1440746.8E-27225329No hitNo description
PfamPF164214.2E-25229328IPR032198E2F transcription factor, CC-MB domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0000902Biological Processcell morphogenesis
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0042023Biological ProcessDNA endoreduplication
GO:0051782Biological Processnegative regulation of cell division
GO:0005667Cellular Componenttranscription factor complex
GO:0005730Cellular Componentnucleolus
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
GO:0044212Molecular Functiontranscription regulatory region DNA binding
GO:0046982Molecular Functionprotein heterodimerization activity
Sequence ? help Back to Top
Protein Sequence    Length: 437 aa     Download sequence    Send to blast
MAVWGDDPSL SNQQSRFQSD TRNPSLNPFF PSSQRKPHLF PFFSCPMNDS SFVSDTRTHC  60
HSDDRQSAFV KLPLKQTNEI DHCKGQTSRQ ATLDGHGEEM KFPSLEPESC VGGKQQHSKS  120
KVSKNAKSGA QRSNAESPNI LNPVVTCRYD SSLGLLTKKF ISLIQEAKDG TLDLNRTADV  180
LEVQKRRIYD ITNVLEGIGL IEKTSKNHIS WKGFDMSGPQ KMDNEVTRLK AEVERLYAEE  240
CRLDDCIREK QELLRAIAGD ENCQKHLFLT EEDITTLPCF QNQTLIAIKA PQASSVEVPD  300
PDEDIGFSQR QFRIIIRSTT GPIDLYLLRT KSLDYSVEDS GCNKLQDAGP FSSLGSEGSG  360
IQKIIPSDFK IDDDYWLRSD PEVSITDLWA NEDWAQENDI FQEDSITSDA SLAQTQPSLR  420
GSLSEPDKNQ AVGCSG*
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1cf7_A5e-25143213273PROTEIN (TRANSCRIPTION FACTOR E2F-4)
Search in ModeBase
Expression -- UniGene ? help Back to Top
UniGene ID E-value Expressed in
Vvi.65350.0fruit| stem
Expression -- Description ? help Back to Top
Source Description
UniprotDEVELOPMENTAL STAGE: Expressed in a cell cycle-dependent manner. Not detected at the G1/S transition, but increases during the progression into S phase and peaks after the passage into G2. {ECO:0000269|PubMed:11669580, ECO:0000269|PubMed:11786543, ECO:0000269|PubMed:12468727}.
UniprotTISSUE SPECIFICITY: Expressed in meristematic areas, vascular tissues, apical part of the roots, cotyledons, upper region of the hypocotyls, trichomes, young flower buds and pollen grains. {ECO:0000269|PubMed:12468727, ECO:0000269|PubMed:16920782}.
Functional Description ? help Back to Top
Source Description
UniProtInvolved in transcriptional repression. May act by repressing E2F-regulated genes in mature differentiated cells, but is not an antagonist of E2FA. Restricts cell division and is involved in the coordination between cell proliferation and endoreduplication during development. May play a role during the transition from skotomorphogenesis to photomorphogenesis. Regulated by phosphorylation-dependent proteolysis via the protein-ubiquitin ligase SCF(SKP2A) complex. {ECO:0000269|PubMed:11786543, ECO:0000269|PubMed:11891240, ECO:0000269|PubMed:12468727, ECO:0000269|PubMed:16920782, ECO:0000269|PubMed:19662336}.
Binding Motif ? help Back to Top
Motif ID Method Source Motif file
MP00190DAPTransfer from AT1G47870Download
Motif logo
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Down-regulated by light. {ECO:0000269|PubMed:12468727, ECO:0000269|PubMed:18424613}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieveRetrieve
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankAM4682831e-118AM468283.2 Vitis vinifera contig VV78X137860.11, whole genome shotgun sequence.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_010664799.10.0PREDICTED: transcription factor E2FC isoform X2
SwissprotQ9FV704e-95E2FC_ARATH; Transcription factor E2FC
TrEMBLF6H0800.0F6H080_VITVI; Uncharacterized protein
STRINGVIT_18s0001g14110.t010.0(Vitis vinifera)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
Representative plantOGRP12251749
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT1G47870.21e-97E2F/DP family protein
Publications ? help Back to Top
  1. Kobayashi K, et al.
    Transcriptional repression by MYB3R proteins regulates plant organ growth.
    EMBO J., 2015. 34(15): p. 1992-2007
    [PMID:26069325]
  2. Li B, et al.
    Network-Guided Discovery of Extensive Epistasis between Transcription Factors Involved in Aliphatic Glucosinolate Biosynthesis.
    Plant Cell, 2018. 30(1): p. 178-195
    [PMID:29317470]
  3. Huntley R, et al.
    The maize retinoblastoma protein homologue ZmRb-1 is regulated during leaf development and displays conserved interactions with G1/S regulators and plant cyclin D (CycD) proteins.
    Plant Mol. Biol., 1998. 37(1): p. 155-69
    [PMID:9620273]