PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Gh_A03G0594
Organism
Gossypium hirsutum
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Malvales; Malvaceae; Malvoideae; Gossypium
Family MYB
Protein Properties Length: 344aa    MW: 37588.8 Da    PI: 4.8354
Description MYB family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Gh_A03G0594genomeNAU-NBIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1Myb_DNA-binding28.53.5e-091445132
                     TSSS-HHHHHHHHHHHHHTTTT-HHHHHHHHT CS
  Myb_DNA-binding  1 rgrWTteEdellvdavkqlGggtWktIartmg 32
                     +g+WT+eEd++l+ +++++G g W+  +++ g
      Gh_A03G0594 14 KGAWTAEEDQKLISYIQKHGEGGWRFLPQKAG 45
                     79***********************9999988 PP
2Myb_DNA-binding53.74.8e-1794138147
                      TSSS-HHHHHHHHHHHHHTTTT-HHHHHHHHTTTS-HHHHHHHHHHH CS
  Myb_DNA-binding   1 rgrWTteEdellvdavkqlGggtWktIartmgkgRtlkqcksrwqky 47 
                      rg +T+eEd+ ++++ ++lG++ W++Iar++  +Rt++++k++w+ +
      Gh_A03G0594  94 RGDFTPEEDKTIIKLQAELGNR-WAAIARHLS-NRTDNEIKNYWNAH 138
                      899*******************.*********.***********976 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PROSITE profilePS500909.907988IPR017877Myb-like domain
SuperFamilySSF466891.65E-7944IPR009057Homeodomain-like
SMARTSM007174.2E-71390IPR001005SANT/Myb domain
PfamPF002491.9E-71445IPR001005SANT/Myb domain
Gene3DG3DSA:1.10.10.603.1E-221595IPR009057Homeodomain-like
CDDcd001677.31E-71688No hitNo description
SuperFamilySSF466891.8E-2274145IPR009057Homeodomain-like
PROSITE profilePS5129425.49889143IPR017930Myb domain
SMARTSM007174.2E-1793141IPR001005SANT/Myb domain
PfamPF002491.6E-1594139IPR001005SANT/Myb domain
Gene3DG3DSA:1.10.10.601.2E-2596143IPR009057Homeodomain-like
CDDcd001671.13E-1297139No hitNo description
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0003677Molecular FunctionDNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 344 aa     Download sequence    Send to blast
MGRTPFCSSD GLKKGAWTAE EDQKLISYIQ KHGEGGWRFL PQKAGNSLGF LPIWALFYFL  60
LLCPCSNFGF AGLQRCGKSC RLRWANYLRP GIKRGDFTPE EDKTIIKLQA ELGNRWAAIA  120
RHLSNRTDNE IKNYWNAHLK KRLANMGADQ VTVSGASSSS GNSDSNAVTN TECAKPQQSE  180
PTKKRSASAL LLNKLATRVT QCVGPLRASQ TLQQPTMPFN GGAENSDIFC HPLPSSTPES  240
TSWADNNNSS NSLTIPECGT TNAIDERDSS SSAGVLNDIV ASEFASPTCV DELSDWVNTN  300
YSIEPEQVQI DYSDSMTVGY GGLWDDDVIV VDDDDYTVGS LGFL
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1mse_C7e-24121432105C-Myb DNA-Binding Domain
1msf_C7e-24121432105C-Myb DNA-Binding Domain
Search in ModeBase
Expression -- Description ? help Back to Top
Source Description
UniprotTISSUE SPECIFICITY: Expressed in trichomes. {ECO:0000269|PubMed:23115560}.
Functional Description ? help Back to Top
Source Description
UniProtTranscription factor involved in tryptophan gene activation and in indole-3-acetic acid (IAA) and indolic glucosinolates (IG) biosynthesis. Acts as a direct transcriptional activator of both Trp synthesis genes and Trp secondary metabolism genes. {ECO:0000269|PubMed:15579661, ECO:0000269|PubMed:23580754, ECO:0000269|PubMed:23943862, ECO:0000269|PubMed:9576939}.
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Up-regulated by herbivory. {ECO:0000269|PubMed:23943862}.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_012470775.10.0PREDICTED: transcription factor MYB34
SwissprotO643993e-58MYB34_ARATH; Transcription factor MYB34
TrEMBLA0A0D2MLR50.0A0A0D2MLR5_GOSRA; Uncharacterized protein
STRINGGorai.003G097900.10.0(Gossypium raimondii)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MalvidsOGEM4282646
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT5G60890.12e-59myb domain protein 34
Publications ? help Back to Top
  1. Grubb CD,Abel S
    Glucosinolate metabolism and its control.
    Trends Plant Sci., 2006. 11(2): p. 89-100
    [PMID:16406306]
  2. De Schutter K, et al.
    Arabidopsis WEE1 kinase controls cell cycle arrest in response to activation of the DNA integrity checkpoint.
    Plant Cell, 2007. 19(1): p. 211-25
    [PMID:17209125]
  3. Kim K,Jiang K,Teng SL,Feldman LJ,Huang H
    Using biologically interrelated experiments to identify pathway genes in Arabidopsis.
    Bioinformatics, 2012. 28(6): p. 815-22
    [PMID:22271267]
  4. Guo R, et al.
    Jasmonic acid and glucose synergistically modulate the accumulation of glucosinolates in Arabidopsis thaliana.
    J. Exp. Bot., 2013. 64(18): p. 5707-19
    [PMID:24151308]
  5. Benstein RM, et al.
    Arabidopsis phosphoglycerate dehydrogenase1 of the phosphoserine pathway is essential for development and required for ammonium assimilation and tryptophan biosynthesis.
    Plant Cell, 2013. 25(12): p. 5011-29
    [PMID:24368794]
  6. Ding Y, et al.
    Four distinct types of dehydration stress memory genes in Arabidopsis thaliana.
    BMC Plant Biol., 2013. 13: p. 229
    [PMID:24377444]
  7. Frerigmann H,Gigolashvili T
    MYB34, MYB51, and MYB122 distinctly regulate indolic glucosinolate biosynthesis in Arabidopsis thaliana.
    Mol Plant, 2014. 7(5): p. 814-28
    [PMID:24431192]
  8. Frerigmann H,Gigolashvili T
    Update on the role of R2R3-MYBs in the regulation of glucosinolates upon sulfur deficiency.
    Front Plant Sci, 2014. 5: p. 626
    [PMID:25426131]
  9. Frerigmann H,Glawischnig E,Gigolashvili T
    The role of MYB34, MYB51 and MYB122 in the regulation of camalexin biosynthesis in Arabidopsis thaliana.
    Front Plant Sci, 2015. 6: p. 654
    [PMID:26379682]
  10. Frerigmann H, et al.
    Regulation of Pathogen-Triggered Tryptophan Metabolism in Arabidopsis thaliana by MYB Transcription Factors and Indole Glucosinolate Conversion Products.
    Mol Plant, 2016. 9(5): p. 682-695
    [PMID:26802248]
  11. Stahl E, et al.
    Regulatory and Functional Aspects of Indolic Metabolism in Plant Systemic Acquired Resistance.
    Mol Plant, 2016. 9(5): p. 662-681
    [PMID:26802249]
  12. Bulgakov VP,Veremeichik GN,Grigorchuk VP,Rybin VG,Shkryl YN
    The rolB gene activates secondary metabolism in Arabidopsis calli via selective activation of genes encoding MYB and bHLH transcription factors.
    Plant Physiol. Biochem., 2016. 102: p. 70-9
    [PMID:26913794]
  13. Miao H, et al.
    Glucose enhances indolic glucosinolate biosynthesis without reducing primary sulfur assimilation.
    Sci Rep, 2016. 6: p. 31854
    [PMID:27549907]