PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

Gh_A08G2289

Organism

Gossypium hirsutum

Taxonomic ID

3635

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Malvales; Malvaceae; Malvoideae; Gossypium

Family

NAC

Protein Properties

Length: 338aa MW: 38453.9 Da PI: 7.5374

Description

NAC family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Gh_A08G2289	genome	NAU-NBI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	NAM	174.5	3.1e-54	9	138	1	128
NAM 1 lppGfrFhPtdeelvveyLkkkvegkkleleevikevdiykvePwdLp.k.kvka.eekewyfFskrdkkyatgkrknratksgyWkatgkdkevlsk 95 +ppGfrFhPtdeel+ +yL+kkv+ + ++l +vi+evd++k+ePwdL+ k ++ + ++ewyfFs++dkky+tg+r+nrat++g+Wkatg+dk+++ + Gh_A08G2289 9 VPPGFRFHPTDEELLYYYLRKKVSYEAIDL-DVIREVDLNKLEPWDLKdKcRIGSgPQNEWYFFSHKDKKYPTGTRTNRATTAGFWKATGRDKAIHLS 105 69**************************.9***********943444443456*********************************** PP NAM 96 kgelvglkktLvfykgrapkgektdWvmheyrl 128 +++++g++ktLvfy+grap+g+ktdW+mheyrl Gh_A08G2289 106 NSKKIGMRKTLVFYTGRAPHGQKTDWIMHEYRL 138 *****************************98 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SuperFamily	SSF101941	7.19E-60	5	158	IPR003441	NAC domain
PROSITE profile	PS51005	58.36	9	158	IPR003441	NAC domain
Pfam	PF02365	3.5E-28	10	138	IPR003441	NAC domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0003677	Molecular Function	DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 338 aa Download sequence Send to blast
MAGNGQLSVP PGFRFHPTDE ELLYYYLRKK VSYEAIDLDV IREVDLNKLE PWDLKDKCRI 60 GSGPQNEWYF FSHKDKKYPT GTRTNRATTA GFWKATGRDK AIHLSNSKKI GMRKTLVFYT 120 GRAPHGQKTD WIMHEYRLDD DDSDVQEDGW VVCRVFKKKN LIRGNFQADF NQEDNNYNHM 180 KNIASSSAHQ MEPRPNNNHL HTLYDYSFDG SMQLPQLFSP ESSAVAASSF ISPLSLNSMD 240 VECSQNLLRL TSSSGGGGGG GGGGLMQQDQ MRYNGEWSFL DKLLTNHPMS LDHHHHHHHQ 300 SQAKYIPSLQ LDHVGSSSQK FPFQYPGCET AEGLKFSK

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
1ut4_A	4e-51	6	160	14	167	NO APICAL MERISTEM PROTEIN
1ut4_B	4e-51	6	160	14	167	NO APICAL MERISTEM PROTEIN
1ut7_A	4e-51	6	160	14	167	NO APICAL MERISTEM PROTEIN
1ut7_B	4e-51	6	160	14	167	NO APICAL MERISTEM PROTEIN
3swm_A	6e-51	6	160	17	170	NAC domain-containing protein 19
3swm_B	6e-51	6	160	17	170	NAC domain-containing protein 19
3swm_C	6e-51	6	160	17	170	NAC domain-containing protein 19
3swm_D	6e-51	6	160	17	170	NAC domain-containing protein 19
3swp_A	6e-51	6	160	17	170	NAC domain-containing protein 19
3swp_B	6e-51	6	160	17	170	NAC domain-containing protein 19
3swp_C	6e-51	6	160	17	170	NAC domain-containing protein 19
3swp_D	6e-51	6	160	17	170	NAC domain-containing protein 19
4dul_A	4e-51	6	160	14	167	NAC domain-containing protein 19
4dul_B	4e-51	6	160	14	167	NAC domain-containing protein 19
Search in ModeBase

Expression -- Description ? help Back to Top
Source	Description
Uniprot	DEVELOPMENTAL STAGE: First expressed at early heart stage onward in all root basal daughter cells resulting from horizontal divisions in the COL progenitors and is later maintained in these cells. Present in root stem cell daughters and accumulates in maturing root cap layers. Detectable from very early stages of lateral root development. {ECO:0000269\|PubMed:19081078, ECO:0000269\|PubMed:20197506}.
Uniprot	TISSUE SPECIFICITY: Accumulates in maturing root cap cells, in both COL and LRC cells. {ECO:0000269\|PubMed:19081078, ECO:0000269\|PubMed:20197506}.

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription regulator. Together with BRN1 and BRN2, regulates cellular maturation of root cap. Represses stem cell-like divisions in the root cap daughter cells, and thus promotes daughter cell fate. Inhibits expression of its positive regulator FEZ in a feedback loop for controlled switches in cell division plane. Promotes the expression of genes involved in secondary cell walls (SCW) biosynthesis. {ECO:0000269\|PubMed:19081078, ECO:0000269\|PubMed:20197506}.

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: By FEZ in oriented-divised root cap stem cells. {ECO:0000269\|PubMed:19081078}.

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	JX617339	1e-122	JX617339.1 Gossypium hirsutum clone NBRI_GE62433 microsatellite sequence.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_016714995.1	0.0	PREDICTED: protein SOMBRERO-like
Swissprot	Q9MA17	1e-122	SMB_ARATH; Protein SOMBRERO
TrEMBL	A0A1U8LKE6	0.0	A0A1U8LKE6_GOSHI; protein SOMBRERO-like
STRING	Gorai.004G268500.1	0.0	(Gossypium raimondii)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Malvids	OGEM6653	25	42

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT1G79580.3	1e-114	NAC family protein

Publications ? help Back to Top
Fendrych M, et al. Programmed cell death controlled by ANAC033/SOMBRERO determines root cap organ size in Arabidopsis. Curr. Biol., 2014. 24(9): p. 931-40 [PMID:24726156] Bennett T,van den Toorn A,Willemsen V,Scheres B Precise control of plant stem cell activity through parallel regulatory inputs. Development, 2014. 141(21): p. 4055-64 [PMID:25256342] Karve R,Suárez-Román F,Iyer-Pascuzzi AS The Transcription Factor NIN-LIKE PROTEIN7 Controls Border-Like Cell Release. Plant Physiol., 2016. 171(3): p. 2101-11 [PMID:27221617] Kamiya M, et al. Control of root cap maturation and cell detachment by BEARSKIN transcription factors in Arabidopsis. Development, 2016. 143(21): p. 4063-4072 [PMID:27803060]