PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Gh_A11G2989
Organism
Gossypium hirsutum
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Malvales; Malvaceae; Malvoideae; Gossypium
Family HSF
Protein Properties Length: 479aa    MW: 52227 Da    PI: 4.5051
Description HSF family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Gh_A11G2989genomeNAU-NBIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1HSF_DNA-bind115.14.5e-36461382103
                   HHHHHHHHHCTGGGTTTSEESSSSSEEEES-HHHHHHHTHHHHSTT--HHHHHHHHHHTTEEE---SSBTTTTXTTSEEEEESXXXXXXXXXXXXXX CS
  HSF_DNA-bind   2 FlkklyeiledeelkeliswsengnsfvvldeeefakkvLpkyFkhsnfaSFvRQLnmYgFkkvkdeekkskskekiweFkhksFkkgkkellekik 98 
                   Fl+k+y++++d++++ ++sws+ +nsf+v+++ efa++vLpkyFkh+nf+SFvRQLn+YgF+kv++++         weF+++ F +g+k+ll +i 
   Gh_A11G2989  46 FLSKTYDMVDDPATDAVVSWSSANNSFIVWNPPEFARDVLPKYFKHNNFSSFVRQLNTYGFRKVDSDR---------WEFANEGFLRGQKDLLLNIS 133
                   9****************************************************************999.........******************** PP

                   XXXXX CS
  HSF_DNA-bind  99 rkkse 103
                   r+k +
   Gh_A11G2989 134 RRKPA 138
                   *9865 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:1.10.10.101.2E-3938129IPR011991Winged helix-turn-helix DNA-binding domain
SuperFamilySSF467854.08E-3541135IPR011991Winged helix-turn-helix DNA-binding domain
SMARTSM004157.6E-6142135IPR000232Heat shock factor (HSF)-type, DNA-binding
PfamPF004474.1E-3246135IPR000232Heat shock factor (HSF)-type, DNA-binding
PRINTSPR000566.5E-204669IPR000232Heat shock factor (HSF)-type, DNA-binding
PRINTSPR000566.5E-208496IPR000232Heat shock factor (HSF)-type, DNA-binding
PROSITE patternPS00434085109IPR000232Heat shock factor (HSF)-type, DNA-binding
PRINTSPR000566.5E-2097109IPR000232Heat shock factor (HSF)-type, DNA-binding
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0005634Cellular Componentnucleus
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
GO:0043565Molecular Functionsequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 479 aa     Download sequence    Send to blast
MDGVNSSSNI QKDDASTSTG GAQTAAQPQP KPKPVVVQSA NAPPPFLSKT YDMVDDPATD  60
AVVSWSSANN SFIVWNPPEF ARDVLPKYFK HNNFSSFVRQ LNTYGFRKVD SDRWEFANEG  120
FLRGQKDLLL NISRRKPAQG HGHQQTQQAH GQSSSGGACV EVGEFGLEEE VEALKRDKNV  180
LMQELVRLRQ QQQSTDNQMQ TMARQLHGME QWQLQMMSFL AKAVQSPGFL AQFMQQKNES  240
NRHITEANKK RRLKQDGIVD NEHSAASDGQ IVKYQPLTND AKAMLRQIVK GDTSTRLDSI  300
NNYHDNFLVG DGLSSSSGLD GGKSSSHASG MTLQEVPPTS GISVGRLSSA ISEIQSSPCT  360
TSSEKITTTQ STDSSALVGG EKVPSISIPQ TNTIMPELSQ IPEIVPESVV DIPTEDCVES  420
ETGNGGFIDP ICLVPLELDD IAPDPDIDAL LDSSSFWDDL IVQGPVPEDI ETISMDDKG
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
5d5u_B5e-284413527129Heat shock factor protein 1
5d5v_B5e-284413527129Heat shock factor protein 1
5d5v_D5e-284413527129Heat shock factor protein 1
Search in ModeBase
Nucleic Localization Signal ? help Back to Top
NLS
No. Start End Sequence
1247254NKKRRLKQ
2248253KKRRLK
Functional Description ? help Back to Top
Source Description
UniProtDNA-binding protein that specifically binds heat shock promoter elements (HSE) and activates transcription. {ECO:0000250}.
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankKR0674020.0KR067402.1 Gossypium hirsutum HSF21 mRNA, complete cds.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_017616537.10.0PREDICTED: heat shock factor protein HSF8-like
SwissprotQ401521e-153HSF8_SOLLC; Heat shock factor protein HSF8
TrEMBLA0A1U8L3Y40.0A0A1U8L3Y4_GOSHI; heat shock factor protein HSF8-like
STRINGGorai.007G033300.10.0(Gossypium raimondii)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MalvidsOGEM64702440
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT4G17750.11e-104heat shock factor 1
Publications ? help Back to Top
  1. Zhu B, et al.
    Identification and characterization of a novel heat shock transcription factor gene, GmHsfA1, in soybeans (Glycine max).
    J. Plant Res., 2006. 119(3): p. 247-56
    [PMID:16570125]
  2. Wang J,Sun N,Deng T,Zhang L,Zuo K
    Genome-wide cloning, identification, classification and functional analysis of cotton heat shock transcription factors in cotton (Gossypium hirsutum).
    BMC Genomics, 2014. 15: p. 961
    [PMID:25378022]
  3. Cai SY, et al.
    HsfA1a upregulates melatonin biosynthesis to confer cadmium tolerance in tomato plants.
    J. Pineal Res., 2017.
    [PMID:28095626]
  4. Zhou J, et al.
    Heat Shock Factor HsfA1a Is Essential for R Gene-Mediated Nematode Resistance and Triggers H2O2 Production1.
    Plant Physiol., 2018. 176(3): p. 2456-2471
    [PMID:29339397]