PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

Gh_D02G2076

Organism

Gossypium hirsutum

Taxonomic ID

3635

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Malvales; Malvaceae; Malvoideae; Gossypium

Family

bHLH

Protein Properties

Length: 133aa MW: 15218.9 Da PI: 10.2084

Description

bHLH family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Gh_D02G2076	genome	NAU-NBI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	HLH	44	3.9e-14	68	114	5	55
HHHHHHHHHHHHHHHHHHHHCTSCCC...TTS-STCHHHHHHHHHHHHHHH CS HLH 5 hnerErrRRdriNsafeeLrellPkaskapskKlsKaeiLekAveYIksLq 55 h Er RR+++++ f++L llP++ +K +K++i+ +Av+YIk Lq Gh_D02G2076 68 HIWTERERRKKMRNMFSNLHALLPHL----PPKADKSTIVDEAVNYIKTLQ 114 6667*******************6....39****************9 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SuperFamily	SSF47459	2.49E-16	61	123	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
PROSITE profile	PS50888	14.062	63	113	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
Gene3D	G3DSA:4.10.280.10	2.7E-15	67	124	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
CDD	cd00083	6.80E-12	68	118	No hit	No description
Pfam	PF00010	2.7E-11	68	114	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
SMART	SM00353	5.6E-9	71	119	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0046983	Molecular Function	protein dimerization activity

Sequence ? help Back to Top
Protein Sequence Length: 133 aa Download sequence Send to blast
MKASCCGKKN HQSRPLSISD NNNNSPGLGS EDKSATNDNN QQQQDNSQAE TKKKKKKGSE 60 SDDEHDMHIW TERERRKKMR NMFSNLHALL PHLPPKADKS TIVDEAVNYI KTLQQTLQNL 120 QKTKAREINP RSH

Expression -- Description ? help Back to Top
Source	Description
Uniprot	DEVELOPMENTAL STAGE: Expressed during seed development (PubMed:18567831). Exclusively expressed in the endosperm of developing seeds (PubMed:18849529). {ECO:0000269\|PubMed:18567831, ECO:0000269\|PubMed:18849529}.
Uniprot	TISSUE SPECIFICITY: Siliques. Not detected in roots, rosette leaves or flowers. Expressed in endosperm cells. {ECO:0000269\|PubMed:12679534, ECO:0000269\|PubMed:18567831}.

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription factor that controls embryo growth (PubMed:18567831, PubMed:18849529, PubMed:23318634). Regulates endosperm breakdown and embryonic epidermal development. Regulates the expression of SBT2.4/ALE1 (PubMed:18849529, PubMed:23318634). Involved in embryonic cuticle formation upstream of SBT2.4/ALE1 (PubMed:23318634). Does not seem to be a general regulator of endosperm patterning. May control specific signaling pathways that coordinate embryo invasion and breakdown of surrounding endosperm tissues (PubMed:18849529). Required for the production the embryo sheath, an extracuticular endosperm-derived structure at the surface of the embryo. Acts upstream of KRS (PubMed:28696222). {ECO:0000269\|PubMed:18567831, ECO:0000269\|PubMed:18849529, ECO:0000269\|PubMed:23318634, ECO:0000269\|PubMed:28696222}.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_022763397.1	7e-41	transcription factor bHLH95-like
Swissprot	Q9FXA3	5e-28	BH095_ARATH; Transcription factor bHLH95
TrEMBL	A0A2P5S2M8	1e-93	A0A2P5S2M8_GOSBA; Uncharacterized protein
STRING	XP_008454949.1	4e-34	(Cucumis melo)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Malvids	OGEM5074	25	49

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT1G49770.1	1e-14	bHLH family protein

Publications ? help Back to Top
Skinner MK,Rawls A,Wilson-Rawls J,Roalson EH Basic helix-loop-helix transcription factor gene family phylogenetics and nomenclature. Differentiation, 2010. 80(1): p. 1-8 [PMID:20219281] Zhang Y, et al. Reduced function of the RNA-binding protein FPA rescues a T-DNA insertion mutant in the Arabidopsis ZHOUPI gene by promoting transcriptional read-through. Plant Mol. Biol., 2016. 91(4-5): p. 549-61 [PMID:27164978] Fourquin C, et al. Mechanical stress mediated by both endosperm softening and embryo growth underlies endosperm elimination in Arabidopsis seeds. Development, 2016. 143(18): p. 3300-5 [PMID:27287798] Du Q,Wang H Retarded Embryo Development 1 (RED1) regulates embryo development, seed maturation and plant growth in Arabidopsis. J Genet Genomics, 2016. 43(7): p. 439-49 [PMID:27477025] Moussu S, et al. ZHOUPI and KERBEROS Mediate Embryo/Endosperm Separation by Promoting the Formation of an Extracuticular Sheath at the Embryo Surface. Plant Cell, 2017. 29(7): p. 1642-1656 [PMID:28696222]