PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Gh_D05G2606
Organism
Gossypium hirsutum
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Malvales; Malvaceae; Malvoideae; Gossypium
Family C2H2
Protein Properties Length: 358aa    MW: 40858.6 Da    PI: 8.2913
Description C2H2 family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Gh_D05G2606genomeNAU-NBIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1zf-C2H219.82.1e-065980223
                 EETTTTEEESSHHHHHHHHHHT CS
      zf-C2H2  2 kCpdCgksFsrksnLkrHirtH 23
                 +C+ Cg sF+ + +Lk+H+++H
  Gh_D05G2606 59 TCEECGASFKKPAYLKQHLQSH 80
                 6*******************99 PP
2zf-C2H216.32.7e-0586110123
                  EEET..TTTEEESSHHHHHHHHHHT CS
      zf-C2H2   1 ykCp..dCgksFsrksnLkrHirtH 23 
                  ++C   dC+ s++rk++L+rH+  H
  Gh_D05G2606  86 FVCLveDCHASYRRKDHLTRHLLQH 110
                  789999***************9887 PP
3zf-C2H213.80.00018115140123
                  EEET..TTTEEESSHHHHHHHHHH.T CS
      zf-C2H2   1 ykCp..dCgksFsrksnLkrHirt.H 23 
                  +kC   +C++ F  + n+krH++  H
  Gh_D05G2606 115 FKCLieNCNREFAFQGNMKRHLKEfH 140
                  799999*****************988 PP
4zf-C2H218.74.8e-06155179123
                  EEET..TTTEEESSHHHHHHHHHHT CS
      zf-C2H2   1 ykCp..dCgksFsrksnLkrHirtH 23 
                  y+C+   Cgk+F  ks Lk+H  +H
  Gh_D05G2606 155 YVCQevGCGKVFEFKSKLKKHEDSH 179
                  99*******************9888 PP
5zf-C2H212.50.00045247271223
                  EET..TTTEEESSHHHHHHHHHH.T CS
      zf-C2H2   2 kCp..dCgksFsrksnLkrHirt.H 23 
                  kC+   C  +Fs+ksnL  H +  H
  Gh_D05G2606 247 KCNfeGCLHTFSNKSNLSLHVKAvH 271
                  79999***************99877 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SMARTSM00355201739IPR015880Zinc finger, C2H2-like
SMARTSM003550.0145880IPR015880Zinc finger, C2H2-like
PROSITE profilePS5015713.365885IPR007087Zinc finger, C2H2
Gene3DG3DSA:3.30.160.606.4E-75979IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
PROSITE patternPS0002806080IPR007087Zinc finger, C2H2
SuperFamilySSF576671.63E-972112No hitNo description
Gene3DG3DSA:3.30.160.603.2E-1180112IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
PROSITE profilePS501579.05886115IPR007087Zinc finger, C2H2
SMARTSM003550.04786110IPR015880Zinc finger, C2H2-like
PROSITE patternPS00028088110IPR007087Zinc finger, C2H2
SuperFamilySSF576674.6E-6113141No hitNo description
Gene3DG3DSA:3.30.160.601.0E-4113137IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
SMARTSM003550.095115140IPR015880Zinc finger, C2H2-like
PROSITE profilePS5015710.72115145IPR007087Zinc finger, C2H2
PROSITE patternPS000280117140IPR007087Zinc finger, C2H2
Gene3DG3DSA:3.30.160.602.1E-7151179IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
SuperFamilySSF576673.57E-5152179No hitNo description
SMARTSM003550.01155179IPR015880Zinc finger, C2H2-like
PROSITE profilePS5015711.053155184IPR007087Zinc finger, C2H2
PROSITE patternPS000280157179IPR007087Zinc finger, C2H2
SMARTSM003551.4187212IPR015880Zinc finger, C2H2-like
PROSITE patternPS000280189212IPR007087Zinc finger, C2H2
SMARTSM0035518215236IPR015880Zinc finger, C2H2-like
SuperFamilySSF576672.48E-7228284No hitNo description
SMARTSM003550.012246271IPR015880Zinc finger, C2H2-like
PROSITE profilePS5015711.219246276IPR007087Zinc finger, C2H2
Gene3DG3DSA:3.30.160.604.3E-5247271IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
PROSITE patternPS000280248271IPR007087Zinc finger, C2H2
Gene3DG3DSA:3.30.160.604.0E-4272299IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
SMARTSM003558.7277303IPR015880Zinc finger, C2H2-like
PROSITE patternPS000280279303IPR007087Zinc finger, C2H2
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0003676Molecular Functionnucleic acid binding
GO:0046872Molecular Functionmetal ion binding
Sequence ? help Back to Top
Protein Sequence    Length: 358 aa     Download sequence    Send to blast
MEEEKVGGAI FKDIRRYYCE FCGICRSKKS LINSHILTHH TDEVNKGGKE EEGASSSNTC  60
EECGASFKKP AYLKQHLQSH SLERPFVCLV EDCHASYRRK DHLTRHLLQH QGKLFKCLIE  120
NCNREFAFQG NMKRHLKEFH DEESSDLDAG SQKQYVCQEV GCGKVFEFKS KLKKHEDSHV  180
KLDSVEAFCS EPGCMKYFTN EQCLKAHVLS SHAYINCQIC GAKQLKKNIK RHLRSHEPGG  240
VESERIKCNF EGCLHTFSNK SNLSLHVKAV HEELKPFACS FFGCGMRFSY KHVRDNHEKS  300
GCHVYTPGNF LETDEQFRSK PRGGLKRTCP TVEMLVRKRV TPPQMDATMD LGPAPACS
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1tf6_A5e-176220719155PROTEIN (TRANSCRIPTION FACTOR IIIA)
1tf6_D5e-176220719155PROTEIN (TRANSCRIPTION FACTOR IIIA)
Search in ModeBase
Expression -- UniGene ? help Back to Top
UniGene ID E-value Expressed in
Ghi.144210.0ovule
Expression -- Description ? help Back to Top
Source Description
UniprotDEVELOPMENTAL STAGE: Both isoforms 1 and 2 transcripts are expressed in seedlings and both TFIIIA and TFIIIA-C are present at similar ratios in 10-day-old seedlings (at protein level). In correlation with the reorganization of 5S rDNA chromatin to a mature state, full-length isoform 1 protein TFIIIA with transcriptional activity accumulates and permits de novo transcription of 5S rRNA. Isoforms 1 and 2 transcripts accumulate in various tissues of the reproductive phase, including flowers and siliques, but only isoform 2 is present in mature seeds. In flowers, both TFIIIA and TFIIIA-C are present at similar ratios (at protein level). Very low amounts of TFIIIA are found in extracts from fresh siliques compared to TFIIIA-C. The amount of full-length TFIIIA protein progressively increases from fresh siliques to seeds concomitant with lower proportions of the shorter TFIIIA-C protein (at protein level) thus leading to 5S rRNA accumulation in the seed. {ECO:0000269|PubMed:22353599}.
UniprotTISSUE SPECIFICITY: Expressed in seedlings, flowers, siliques and seeds. {ECO:0000269|PubMed:22353599}.
Functional Description ? help Back to Top
Source Description
UniProtEssential protein (PubMed:22353599). Isoform 1 is a transcription activator the binds both 5S rDNA and 5S rRNA and stimulates the transcription of 5S rRNA gene (PubMed:12711688, PubMed:22353599). Isoform 1 regulates 5S rRNA levels during development (PubMed:22353599). {ECO:0000269|PubMed:12711688, ECO:0000269|PubMed:22353599}.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_016686897.10.0PREDICTED: transcription factor IIIA-like isoform X1
SwissprotQ84MZ41e-147TF3A_ARATH; Transcription factor IIIA
TrEMBLA0A1U8J9850.0A0A1U8J985_GOSHI; transcription factor IIIA-like isoform X1
STRINGGorai.009G288800.10.0(Gossypium raimondii)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MalvidsOGEM47142852
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT1G72050.21e-150transcription factor IIIA