PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Gh_D05G2787
Organism
Gossypium hirsutum
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Malvales; Malvaceae; Malvoideae; Gossypium
Family NAC
Protein Properties Length: 462aa    MW: 51571.6 Da    PI: 5.9334
Description NAC family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Gh_D05G2787genomeNAU-NBIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1NAM172.51.3e-53331601128
          NAM   1 lppGfrFhPtdeelvveyLkkkvegkkleleevikevdiykvePwdLp..kkvkaeekewyfFskrdkkyatgkrknratksgyWkatgkdkevlskk 96 
                  l+pGfrFhPtdeelv++yLk+kv++k+ ++ ++i+evdiyk+ePw+L   +k+k++++ewyfFs  dkky +g r nrat +gyWkatgkd+ev + +
  Gh_D05G2787  33 LAPGFRFHPTDEELVSYYLKRKVTNKPARF-DAIAEVDIYKHEPWNLSdkSKLKTRDQEWYFFSLLDKKYGNGGRMNRATGQGYWKATGKDREVRH-N 128
                  579************************999.99**************85348889999**************************************.9 PP

          NAM  97 gelvglkktLvfykgrapkgektdWvmheyrl 128
                  ++l+g+kktLvf++g+ap+g +t+Wvmheyrl
  Gh_D05G2787 129 SQLIGMKKTLVFHSGKAPDGLRTNWVMHEYRL 160
                  9*****************************98 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SuperFamilySSF1019413.01E-6029182IPR003441NAC domain
PROSITE profilePS5100556.99233182IPR003441NAC domain
PfamPF023651.0E-2735160IPR003441NAC domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0003677Molecular FunctionDNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 462 aa     Download sequence    Send to blast
MGRETSLVAD PGPTAVATAT ATAAKTGSSA TALAPGFRFH PTDEELVSYY LKRKVTNKPA  60
RFDAIAEVDI YKHEPWNLSD KSKLKTRDQE WYFFSLLDKK YGNGGRMNRA TGQGYWKATG  120
KDREVRHNSQ LIGMKKTLVF HSGKAPDGLR TNWVMHEYRL IEEELERIGA LQGYVLCRVI  180
HKNNIGAPNG NRYAPFIEAE WDDGSAGLVP GLDTEDDVAA GNDSIARNDV AATENAATES  240
NGVLRISSEQ QDIEHPDEDA PPSDDVPRES SNERTDDCTL LPPFKIERSD YCPPLCMPNR  300
EAPLSLFGHK RRRHNDFGPN HANVTENSTR NVTENSTRMT QDRWSSTTTT TTTITTPPPP  360
PSSATTMAVS ALLEFSLMES MEPKENHHVP PTPKYNATTN LNSMVPPSCM KLINYLQNEI  420
HKTSIERETL KLEMMSAQTM IDILQSKIDF LSKENEDLKK SN
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
3swm_A5e-473218419170NAC domain-containing protein 19
3swm_B5e-473218419170NAC domain-containing protein 19
3swm_C5e-473218419170NAC domain-containing protein 19
3swm_D5e-473218419170NAC domain-containing protein 19
3swp_A5e-473218419170NAC domain-containing protein 19
3swp_B5e-473218419170NAC domain-containing protein 19
3swp_C5e-473218419170NAC domain-containing protein 19
3swp_D5e-473218419170NAC domain-containing protein 19
Search in ModeBase
Expression -- UniGene ? help Back to Top
UniGene ID E-value Expressed in
Ghi.57600.0boll| ovule| stem
Expression -- Description ? help Back to Top
Source Description
UniprotTISSUE SPECIFICITY: Mostly expressed in floral organs, and, at low levels, in other organs. {ECO:0000269|PubMed:25578968}.
Functional Description ? help Back to Top
Source Description
UniProtTranscriptional repressor that binds to the motif 5'-(C/T)A(C/A)G-3' in the promoter of target genes (PubMed:25578968). Binds also to the 5'-CTTGNNNNNCAAG-3' consensus sequence in chromatin (PubMed:26617990). Can bind to the mitochondrial dysfunction motif (MDM) present in the upstream regions of mitochondrial dysfunction stimulon (MDS) genes involved in mitochondrial retrograde regulation (MRR) (PubMed:24045019). Together with NAC050 and JMJ14, regulates gene expression and flowering time by associating with the histone demethylase JMJ14, probably by the promotion of RNA-mediated gene silencing (PubMed:25578968, PubMed:26617990). Regulates siRNA-dependent post-transcriptional gene silencing (PTGS) through SGS3 expression modulation (PubMed:28207953). Required during pollen development (PubMed:19237690). {ECO:0000269|PubMed:19237690, ECO:0000269|PubMed:24045019, ECO:0000269|PubMed:25578968, ECO:0000269|PubMed:26617990, ECO:0000269|PubMed:28207953}.
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Induced by type III effector proteins (TTEs) secreted by the pathogenic bacteria P.syringae pv. tomato DC3000 during basal defense. {ECO:0000269|PubMed:16553893}.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_016685920.10.0PREDICTED: NAC domain-containing protein 86-like isoform X1
SwissprotQ9SQY01e-144NAC52_ARATH; NAC domain containing protein 52
TrEMBLA0A1U8J6H10.0A0A1U8J6H1_GOSHI; NAC domain-containing protein 86-like isoform X1
STRINGGorai.009G309300.10.0(Gossypium raimondii)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MalvidsOGEM17802880
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT3G10490.21e-130NAC domain containing protein 52
Publications ? help Back to Top
  1. Higgins JD,Ferdous M,Osman K,Franklin FC
    The RecQ helicase AtRECQ4A is required to remove inter-chromosomal telomeric connections that arise during meiotic recombination in Arabidopsis.
    Plant J., 2011. 65(3): p. 492-502
    [PMID:21265901]
  2. Ding Y, et al.
    Four distinct types of dehydration stress memory genes in Arabidopsis thaliana.
    BMC Plant Biol., 2013. 13: p. 229
    [PMID:24377444]
  3. Zhang S, et al.
    C-terminal domains of a histone demethylase interact with a pair of transcription factors and mediate specific chromatin association.
    Cell Discov, 2019.
    [PMID:26617990]
  4. Butel N,Le Masson I,Bouteiller N,Vaucheret H,Elmayan T
    sgs1: a neomorphic nac52 allele impairing post-transcriptional gene silencing through SGS3 downregulation.
    Plant J., 2017. 90(3): p. 505-519
    [PMID:28207953]
  5. Elmayan T, et al.
    Arabidopsis mutants impaired in cosuppression.
    Plant Cell, 1998. 10(10): p. 1747-58
    [PMID:9761800]