PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Gh_D13G1951
Organism
Gossypium hirsutum
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Malvales; Malvaceae; Malvoideae; Gossypium
Family ARR-B
Protein Properties Length: 615aa    MW: 67196.9 Da    PI: 6.7945
Description ARR-B family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Gh_D13G1951genomeNAU-NBIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1G2-like88.56e-28199252155
      G2-like   1 kprlrWtpeLHerFveaveqLGGsekAtPktilelmkvkgLtlehvkSHLQkYRl 55 
                  kpr++W+ eLH++Fv av+qL G++kA+Pk+ilelm+v+ Lt+e+v+SHLQk+Rl
  Gh_D13G1951 199 KPRVVWSVELHRKFVAAVNQL-GIDKAVPKKILELMNVEKLTRENVASHLQKFRL 252
                  79*******************.********************************8 PP
2Response_reg79.51.2e-26201281109
                   EEEESSSHHHHHHHHHHHHHTTCEEEEEESSHHHHHHHHHHHH..ESEEEEESSCTTSEHHHHHHHHHHHTTTSEEEEEESTTTHHHHHHHHHTTES CS
  Response_reg   1 vlivdDeplvrellrqalekegyeevaeaddgeealellkekd..pDlillDiempgmdGlellkeireeepklpiivvtahgeeedalealkaGak 95 
                   vl vdD+p+ + ll ++l++ +y +v+++++++ al++l+e++  +Dl++ D+ mp+mdG++ll++   e  +lp+i+++a+g+ +++ + +  Ga 
   Gh_D13G1951  20 VLAVDDDPTCLLLLGTLLRRCQY-HVTTTSQAKTALKMLRENKnkFDLVISDVHMPDMDGFKLLEHVGLEM-DLPVIMLSANGDTKLVMKGITHGAC 114
                   799********************.***************888888**********************6644.8************************ PP

                   EEEESS--HHHHHH CS
  Response_reg  96 dflsKpfdpeelvk 109
                   d+l Kp+ +eel +
   Gh_D13G1951 115 DYLLKPVRIEELQN 128
                   ***********986 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PIRSFPIRSF0363921.3E-1691609IPR017053Response regulator B-type, plant
Gene3DG3DSA:3.40.50.23001.4E-4217141No hitNo description
SuperFamilySSF521721.38E-3517138IPR011006CheY-like superfamily
SMARTSM004487.3E-3318130IPR001789Signal transduction response regulator, receiver domain
PROSITE profilePS5011042.37219134IPR001789Signal transduction response regulator, receiver domain
PfamPF000724.0E-2420128IPR001789Signal transduction response regulator, receiver domain
CDDcd001565.25E-2421133No hitNo description
Gene3DG3DSA:1.10.10.609.8E-30196257IPR009057Homeodomain-like
PROSITE profilePS5129411.466196255IPR017930Myb domain
SuperFamilySSF466891.42E-19197256IPR009057Homeodomain-like
TIGRFAMsTIGR015574.9E-25199252IPR006447Myb domain, plants
PfamPF002494.6E-6201250IPR001005SANT/Myb domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0000160Biological Processphosphorelay signal transduction system
GO:0003677Molecular FunctionDNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 615 aa     Download sequence    Send to blast
MTVEQIVSEG KDQFPIGMRV LAVDDDPTCL LLLGTLLRRC QYHVTTTSQA KTALKMLREN  60
KNKFDLVISD VHMPDMDGFK LLEHVGLEMD LPVIMLSANG DTKLVMKGIT HGACDYLLKP  120
VRIEELQNIW QHVVRRKKKD RCNSGSKDKP HPDSGEDAGI GNVDNNGKLN KKRKDQNEDE  180
DDERDENGHD NEDPSAQKKP RVVWSVELHR KFVAAVNQLG IDKAVPKKIL ELMNVEKLTR  240
ENVASHLQKF RLYLKRISCV ANQQANMAAA LGTADSAYLR MGSLNGLGNF HTLAGSDQLH  300
NAAFRSFPPS GVLGRLNTPA GLGIRGLPSP GTIQLGHVQN SGNPTNDLSK LQSFVPGNHN  360
TNILQGMPMS LELDRLQHNK SVGHIGELPT TDSTTVFPGS GSLVDARITG FSNNPLLGVT  420
SNSLMLEGSS QQATSHTSVS AIGFQNGNAL SDFTLIAPAS NQLQDSKADS QGQASLINCN  480
AGQIIRSAPQ EWNAPRKDAP YQSHALINSS IPINSAMIQL GQCLDRNNSI FHRTTDLDSV  540
GPLNFVDPLS IKHSEGDNYI MEPSVIEKEG YLMFQPRPHG SHVPDNTGSL KDLASAMMKQ  600
EDDFGCNGYS LRTSI
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1irz_A3e-26195258164ARR10-B
Search in ModeBase
Nucleic Localization Signal ? help Back to Top
NLS
No. Start End Sequence
1134139RRKKKD
Expression -- Description ? help Back to Top
Source Description
UniprotDEVELOPMENTAL STAGE: Detected immediately after seed germination. {ECO:0000269|PubMed:17363254}.
UniprotTISSUE SPECIFICITY: Detected in the whole plant. Predominantly expressed in leaves. Expressed at the root transition zone (PubMed:17363254). {ECO:0000269|PubMed:15173562, ECO:0000269|PubMed:17363254}.
Functional Description ? help Back to Top
Source Description
UniProtTranscriptional activator that binds specifically to the DNA sequence 5'-[AG]GATT-3'. Functions as a response regulator involved in His-to-Asp phosphorelay signal transduction system. Phosphorylation of the Asp residue in the receiver domain activates the ability of the protein to promote the transcription of target genes. Could directly activate some type-A response regulators in response to cytokinins. Involved in the root-meristem size determination through the regulation of cell differentiation (PubMed:17363254). Involved in activating SHY2 during meristem growth and controls PIN expression via activation of SHY2 (PubMed:20605455). {ECO:0000250|UniProtKB:Q940D0, ECO:0000269|PubMed:17363254, ECO:0000269|PubMed:20605455}.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_016667985.10.0PREDICTED: two-component response regulator ARR12-like
SwissprotP625981e-151ARR12_ARATH; Two-component response regulator ARR12
TrEMBLA0A1U8HPL10.0A0A1U8HPL1_GOSHI; Two-component response regulator
STRINGGorai.010G243900.10.0(Gossypium raimondii)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MalvidsOGEM19812879
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT2G25180.11e-142response regulator 12
Publications ? help Back to Top
  1. Takahashi N, et al.
    Cytokinins control endocycle onset by promoting the expression of an APC/C activator in Arabidopsis roots.
    Curr. Biol., 2013. 23(18): p. 1812-7
    [PMID:24035544]
  2. Cortleven A, et al.
    A novel protective function for cytokinin in the light stress response is mediated by the Arabidopsis histidine kinase2 and Arabidopsis histidine kinase3 receptors.
    Plant Physiol., 2014. 164(3): p. 1470-83
    [PMID:24424319]
  3. Kim HJ,Kieber JJ,Schaller GE
    The rice F-box protein KISS ME DEADLY2 functions as a negative regulator of cytokinin signalling.
    Plant Signal Behav, 2013. 8(12): p. e26434
    [PMID:24675172]
  4. Choi SH, et al.
    Gene duplication of type-B ARR transcription factors systematically extends transcriptional regulatory structures in Arabidopsis.
    Sci Rep, 2014. 4: p. 7197
    [PMID:25425016]
  5. Jiang L, et al.
    Strigolactones spatially influence lateral root development through the cytokinin signaling network.
    J. Exp. Bot., 2016. 67(1): p. 379-89
    [PMID:26519957]
  6. Cortleven A, et al.
    Cytokinin Regulates the Etioplast-Chloroplast Transition through the Two-Component Signaling System and Activation of Chloroplast-Related Genes.
    Plant Physiol., 2016. 172(1): p. 464-78
    [PMID:27388681]
  7. Kobayashi K, et al.
    Shoot Removal Induces Chloroplast Development in Roots via Cytokinin Signaling.
    Plant Physiol., 2017. 173(4): p. 2340-2355
    [PMID:28193764]
  8. Zhang TQ, et al.
    A Two-Step Model for de Novo Activation of WUSCHEL during Plant Shoot Regeneration.
    Plant Cell, 2017. 29(5): p. 1073-1087
    [PMID:28389585]
  9. Meng WJ, et al.
    Type-B ARABIDOPSIS RESPONSE REGULATORs Specify the Shoot Stem Cell Niche by Dual Regulation of WUSCHEL.
    Plant Cell, 2017. 29(6): p. 1357-1372
    [PMID:28576846]
  10. Kobayashi K,Iwase A
    Simultaneous but spatially different regulation of non-photosynthetic callus formation and photosynthetic root development after shoot removal.
    Plant Signal Behav, 2017. 12(6): p. e1338999
    [PMID:28594268]
  11. Dai X, et al.
    ARR12 promotes de novo shoot regeneration in Arabidopsis thaliana via activation of WUSCHEL expression.
    J Integr Plant Biol, 2017. 59(10): p. 747-758
    [PMID:28681564]
  12. Zhang F,May A,Irish VF
    Type-B ARABIDOPSIS RESPONSE REGULATORs Directly Activate WUSCHEL.
    Trends Plant Sci., 2017. 22(10): p. 815-817
    [PMID:28886911]
  13. Yan Z, et al.
    Type B Response Regulators Act As Central Integrators in Transcriptional Control of the Auxin Biosynthesis Enzyme TAA1.
    Plant Physiol., 2017. 175(3): p. 1438-1454
    [PMID:28931628]
  14. Bustillo-Avendaño E, et al.
    Regulation of Hormonal Control, Cell Reprogramming, and Patterning during De Novo Root Organogenesis.
    Plant Physiol., 2018. 176(2): p. 1709-1727
    [PMID:29233938]