PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Glyma.04G130300.1.p
Common NameGLYMA_04G130300, LOC100819116
Organism
Glycine max
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Fabales; Fabaceae; Papilionoideae; Phaseoleae; Glycine; Soja
Family C2H2
Protein Properties Length: 435aa    MW: 50101.3 Da    PI: 7.7188
Description C2H2 family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Glyma.04G130300.1.pgenomeJGIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1zf-C2H2120.00066192214123
                          EEETTTTEEESSHHHHHHHHHHT CS
              zf-C2H2   1 ykCpdCgksFsrksnLkrHirtH 23 
                          y C+ C    +rk++L+rH+r++
  Glyma.04G130300.1.p 192 YFCEFCLNFMKRKEQLQRHMRKC 214
                          78*******************98 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SuperFamilySSF541601.19E-2342159IPR016197Chromo domain-like
Gene3DG3DSA:2.30.30.2701.0E-3644118No hitNo description
PfamPF117172.5E-2048106IPR025995RNA binding activity-knot of a chromodomain
SMARTSM002981.1E-662121IPR000953Chromo/chromo shadow domain
CDDcd000241.96E-662106No hitNo description
Gene3DG3DSA:2.30.30.2701.0E-36153203No hitNo description
PROSITE profilePS5172675.584158429IPR002717Histone acetyltransferase domain, MYST-type
SuperFamilySSF557292.05E-111159430IPR016181Acyl-CoA N-acyltransferase
Gene3DG3DSA:3.40.630.304.1E-73217360IPR016181Acyl-CoA N-acyltransferase
PfamPF018533.0E-84219396IPR002717Histone acetyltransferase domain, MYST-type
CDDcd043010.00243270328No hitNo description
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0016573Biological Processhistone acetylation
GO:0005634Cellular Componentnucleus
GO:0004402Molecular Functionhistone acetyltransferase activity
Sequence ? help Back to Top
Protein Sequence    Length: 435 aa     Download sequence    Send to blast
MGSLEAPTAA ENGSAPAAGN GKSPSVNGAE AALEPDASKR RRSSVLPLEV GTRVMCRWRD  60
NKYHPVKVIE RRKVPNVIPN DYEYYVHYTE FNRRLDEWVK LDQLDLNSVE AVVDEKVEEK  120
GATGLKMTRH QKRKIDETHV EGHEELDAAS LREHEEFTKV KNIATIELGR YEIETWYFSP  180
FPPEYNDCLK LYFCEFCLNF MKRKEQLQRH MRKCDLKHPP GDEIYRSGTL SMFEVDGKKN  240
KVYGQNLCYL AKLFLDHKTL YYDVDLFLFY VLCECDDRGC HMVGYFSKEK HSEESYNLAC  300
ILTLPPYQRK GYGKFLIAFS YELSKKEGKV GTPERPLSDL GLLSYRGYWT RVLLDILKKH  360
KGNISIKELS DMTAIKAEDI LTTLQSLELI QYRKGQHVIC ADPKVLDRHL KAAGRGGLEV  420
DVSKLIWTPY KEQS*
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
4dnc_A1e-1181544331282Histone acetyltransferase KAT8
4dnc_B1e-1181544331282Histone acetyltransferase KAT8
Search in ModeBase
Expression -- UniGene ? help Back to Top
UniGene ID E-value Expressed in
Gma.85500.0epicotyl| root| seed coat| somatic embryo| stem
Expression -- Description ? help Back to Top
Source Description
UniprotTISSUE SPECIFICITY: Expressed in cotyledons, leaves, stems, roots and, at higher levels in developing flowers, particularly in the anthers and gynoecia (PubMed:19040736). Constitutively expressed in all tissues, predominantly in shoot apical meristem (PubMed:23273925). {ECO:0000269|PubMed:19040736, ECO:0000269|PubMed:23273925}.
Functional Description ? help Back to Top
Source Description
UniProtHistone acetyltransferase which may be involved in transcriptional activation. Acetylates 'Lys-5' of histone H4 (H4K5ac) (PubMed:17877703, PubMed:19040736, PubMed:22170978, PubMed:23273925). Essential for gametophyte development (PubMed:19040736). Involved in DNA repair after UV-B exposure (PubMed:22170978). Negative regulator of flowering controlling the H4K5ac levels in the FLC chromatin (PubMed:23273925). {ECO:0000269|PubMed:17877703, ECO:0000269|PubMed:19040736, ECO:0000269|PubMed:22170978, ECO:0000269|PubMed:23273925}.
Cis-element ? help Back to Top
SourceLink
PlantRegMapGlyma.04G130300.1.p
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Up-regulated upon UV-B exposure. {ECO:0000269|PubMed:22170978}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankBT1420750.0BT142075.1 Lotus japonicus clone JCVI-FLLj-11A9 unknown mRNA.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_003522879.10.0histone acetyltransferase of the MYST family 1
SwissprotQ9FLF70.0MYST1_ARATH; Histone acetyltransferase of the MYST family 1
TrEMBLA0A0R0K7Z30.0A0A0R0K7Z3_SOYBN; Histone acetyltransferase
STRINGGLYMA04G16180.10.0(Glycine max)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
FabidsOGEF70661011
Representative plantOGRP389045
Publications ? help Back to Top
  1. Latrasse D, et al.
    The MYST histone acetyltransferases are essential for gametophyte development in Arabidopsis.
    BMC Plant Biol., 2008. 8: p. 121
    [PMID:19040736]
  2. Campi M,D'Andrea L,Emiliani J,Casati P
    Participation of chromatin-remodeling proteins in the repair of ultraviolet-B-damaged DNA.
    Plant Physiol., 2012. 158(2): p. 981-95
    [PMID:22170978]
  3. Bari A,Orazova S,Ivashchenko A
    miR156- and miR171-binding sites in the protein-coding sequences of several plant genes.
    Biomed Res Int, 2013. 2013: p. 307145
    [PMID:23936788]
  4. Xu Y, et al.
    Arabidopsis MRG domain proteins bridge two histone modifications to elevate expression of flowering genes.
    Nucleic Acids Res., 2014. 42(17): p. 10960-74
    [PMID:25183522]
  5. Raevsky AV,Sharifi M,Samofalova DA,Karpov PA,Blume YB
    3D structure prediction of histone acetyltransferase proteins of the MYST family and their interactome in Arabidopsis thaliana.
    J Mol Model, 2016. 22(11): p. 256
    [PMID:27709438]
  6. Fina JP,Masotti F,Rius SP,Crevacuore F,Casati P
    HAC1 and HAF1 Histone Acetyltransferases Have Different Roles in UV-B Responses in Arabidopsis.
    Front Plant Sci, 2017. 8: p. 1179
    [PMID:28740501]