PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

Glyma.20G185800.1.p

Common Name

GLYMA_20G185800, LOC100787422

Organism

Glycine max

Taxonomic ID

3847

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Fabales; Fabaceae; Papilionoideae; Phaseoleae; Glycine; Soja

Family

NAC

Protein Properties

Length: 443aa MW: 49829 Da PI: 5.3281

Description

NAC family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Glyma.20G185800.1.p	genome	JGI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	NAM	102.9	4.2e-32	76	215	1	128
NAM 1 lppGfrFhPtdeelvveyLkkkvegkk.....leleevikevd..iykvePwdLpkkvkaeekewyfFskrdkkyatgkrknra.....t 78 lp G++F+P+d+e++++ L+k +g++ ++++ + evd i++++P++Lp vk++ ++ +fF++ k+y+tg+rk+r+ Glyma.20G185800.1.p 76 LPIGVKFDPSDQEIIWHLLAKVGAGNSkphpfIDEFITTLEVDdgICYTHPQHLP-GVKQDGSSSHFFHRVIKAYNTGSRKRRKicgqdF 164 699**********888888777776776654444444444345******.777888999**************7444444 PP NAM 79 ksgyWkatgkdkevlskkgelvglkktLvfy..kgrapkgektdWvmheyrl 128 + +W++tg++k+v+ +g ++g+kk++v+y r k+ekt+Wvmh+y+l Glyma.20G185800.1.p 165 GDVRWHKTGRTKPVIL-NGIQKGCKKIMVLYisPVRGGKSEKTNWVMHQYHL 215 4889********.999*******6545888888*******98 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SuperFamily	SSF101941	2.35E-39	61	234	IPR003441	NAC domain
PROSITE profile	PS51005	31.209	76	234	IPR003441	NAC domain
Pfam	PF02365	9.8E-14	77	215	IPR003441	NAC domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0005634	Cellular Component	nucleus
GO:0003677	Molecular Function	DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 443 aa Download sequence Send to blast
MLKTILNLSH LIASFSDLFP MAGPSWLVDK SRIATKIKSA SGTCGKVIWK SNPSRACPSC 60 HHVIDNSDVA QEWPGLPIGV KFDPSDQEII WHLLAKVGAG NSKPHPFIDE FITTLEVDDG 120 ICYTHPQHLP GVKQDGSSSH FFHRVIKAYN TGSRKRRKIC GQDFGDVRWH KTGRTKPVIL 180 NGIQKGCKKI MVLYISPVRG GKSEKTNWVM HQYHLGTEED EKDGEYVISK VFYQQQQVKF 240 GEKDDQDIPE ITEATTVKVD PATPKSVTPE PPRIEKRCSN LDLGQESHHI PQHPQTDYLD 300 DLQAVCEDLA KDDLLIVETQ NNEAIDNIEN NAEEDSKWWD SESQNLLSSQ QLVEALFLCD 360 DLLQSQSPKR DEENEHKKRP SLSVYADLGP EHLKKDIEEC QNLVLDPANV VPETPPSEFR 420 LSQLDFSSQD SFVSWCANKA ID*

Sequence ? help Back to Top

Protein Sequence Length: 443 aa Download sequence Send to blast

MLKTILNLSH LIASFSDLFP MAGPSWLVDK SRIATKIKSA SGTCGKVIWK SNPSRACPSC  60
HHVIDNSDVA QEWPGLPIGV KFDPSDQEII WHLLAKVGAG NSKPHPFIDE FITTLEVDDG  120
ICYTHPQHLP GVKQDGSSSH FFHRVIKAYN TGSRKRRKIC GQDFGDVRWH KTGRTKPVIL  180
NGIQKGCKKI MVLYISPVRG GKSEKTNWVM HQYHLGTEED EKDGEYVISK VFYQQQQVKF  240
GEKDDQDIPE ITEATTVKVD PATPKSVTPE PPRIEKRCSN LDLGQESHHI PQHPQTDYLD  300
DLQAVCEDLA KDDLLIVETQ NNEAIDNIEN NAEEDSKWWD SESQNLLSSQ QLVEALFLCD  360
DLLQSQSPKR DEENEHKKRP SLSVYADLGP EHLKKDIEEC QNLVLDPANV VPETPPSEFR  420
LSQLDFSSQD SFVSWCANKA ID*

Expression -- Description ? help Back to Top
Source	Description
Uniprot	TISSUE SPECIFICITY: Expressed in shoot and root apical meristems, in lateral root primordia, in the vasculature of young leaves and in the root stele. {ECO:0000269\|PubMed:23907539}.

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription factor regulating the transcriptional activation response to gamma irradiation (PubMed:19549833). Required for stem-cell death induced by UVB or by gamma irradiation (PubMed:20634150). Not required for ATM activation, but participates in pathways governed by both ATM and ATR sensor kinases (PubMed:19549833). Involved in DNA damage response (DDR) system that regulates cell cycle arrest (PubMed:24399300). Functional homolog of animal p53 (PubMed:24736489). Regulates SMR5 and SMR7 transcription (PubMed:24399300). Regulates DNA repair and cytokinin signaling separately and plays a key role in controlling lateral root formation under genotoxic stress. {ECO:0000269\|PubMed:19549833, ECO:0000269\|PubMed:20634150, ECO:0000269\|PubMed:24399300, ECO:0000305\|PubMed:24736489}.

Cis-element ? help Back to Top
Source	Link
PlantRegMap	Glyma.20G185800.1.p

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Not induced by zeocin or ionizing radiation treatment. {ECO:0000269\|PubMed:23907539}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	BT096579	0.0	BT096579.1 Soybean clone JCVI-FLGm-20J20 unknown mRNA.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_006605343.1	0.0	uncharacterized protein LOC100787422 isoform X1
Swissprot	Q6NQK2	1e-164	NAC8_ARATH; SUPPRESSOR OF GAMMA RESPONSE 1
TrEMBL	K7N4B9	0.0	K7N4B9_SOYBN; Uncharacterized protein
STRING	GLYMA20G32690.2	0.0	(Glycine max)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Fabids	OGEF5662	33	54
Representative plant	OGRP8264	10	16

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT1G25580.1	1e-154	NAC family protein

Link Out ? help Back to Top
Phytozome	Glyma.20G185800.1.p
Entrez Gene	100787422

Publications ? help Back to Top
Yi D, et al. The Arabidopsis SIAMESE-RELATED cyclin-dependent kinase inhibitors SMR5 and SMR7 regulate the DNA damage checkpoint in response to reactive oxygen species. Plant Cell, 2014. 26(1): p. 296-309 [PMID:24399300] Biever JJ,Brinkman D,Gardner G UV-B inhibition of hypocotyl growth in etiolated Arabidopsis thaliana seedlings is a consequence of cell cycle arrest initiated by photodimer accumulation. J. Exp. Bot., 2014. 65(11): p. 2949-61 [PMID:24591052] Hu Z,Cools T,Kalhorzadeh P,Heyman J,De Veylder L Deficiency of the Arabidopsis helicase RTEL1 triggers a SOG1-dependent replication checkpoint in response to DNA cross-links. Plant Cell, 2015. 27(1): p. 149-61 [PMID:25595823] Chen P,Umeda M DNA double-strand breaks induce the expression of flavin-containing monooxygenase and reduce root meristem size in Arabidopsis thaliana. Genes Cells, 2015. 20(8): p. 636-46 [PMID:26033196] Sjogren CA,Bolaris SC,Larsen PB Aluminum-Dependent Terminal Differentiation of the Arabidopsis Root Tip Is Mediated through an ATR-, ALT2-, and SOG1-Regulated Transcriptional Response. Plant Cell, 2015. 27(9): p. 2501-15 [PMID:26320227] Yoshiyama KO SOG1: a master regulator of the DNA damage response in plants. Genes Genet. Syst., 2016. 90(4): p. 209-16 [PMID:26617076] Weimer AK, et al. The plant-specific CDKB1-CYCB1 complex mediates homologous recombination repair in Arabidopsis. EMBO J., 2016. 35(19): p. 2068-2086 [PMID:27497297] Davis OM,Ogita N,Inagaki S,Takahashi N,Umeda M DNA damage inhibits lateral root formation by up-regulating cytokinin biosynthesis genes in Arabidopsis thaliana. Genes Cells, 2016. 21(11): p. 1195-1208 [PMID:27658920] Pedroza-García JA, et al. Function of the Plant DNA Polymerase Epsilon in Replicative Stress Sensing, a Genetic Analysis. Plant Physiol., 2017. 173(3): p. 1735-1749 [PMID:28153919] Horvath BM, et al. Arabidopsis RETINOBLASTOMA RELATED directly regulates DNA damage responses through functions beyond cell cycle control. EMBO J., 2017. 36(9): p. 1261-1278 [PMID:28320736] Sjogren CA,Larsen PB SUV2, which encodes an ATR-related cell cycle checkpoint and putative plant ATRIP, is required for aluminium-dependent root growth inhibition in Arabidopsis. Plant Cell Environ., 2017. 40(9): p. 1849-1860 [PMID:28556304] Yoshiyama KO,Kaminoyama K,Sakamoto T,Kimura S Increased Phosphorylation of Ser-Gln Sites on SUPPRESSOR OF GAMMA RESPONSE1 Strengthens the DNA Damage Response in Arabidopsis thaliana. Plant Cell, 2017. 29(12): p. 3255-3268 [PMID:29208704] Johnson RA, et al. SUPPRESSOR OF GAMMA RESPONSE1 Links DNA Damage Response to Organ Regeneration. Plant Physiol., 2018. 176(2): p. 1665-1675 [PMID:29222192] Ogita N, et al. Identifying the target genes of SUPPRESSOR OF GAMMA RESPONSE 1, a master transcription factor controlling DNA damage response in Arabidopsis. Plant J., 2018. 94(3): p. 439-453 [PMID:29430765] Cao X, et al. Roles of MSH2 and MSH6 in cadmium-induced G2/M checkpoint arrest in Arabidopsis roots. Chemosphere, 2018. 201: p. 586-594 [PMID:29533809]