PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

Glyma.U015500.1.p

Common Name

GLYMA_U015500

Organism

Glycine max

Taxonomic ID

3847

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Fabales; Fabaceae; Papilionoideae; Phaseoleae; Glycine; Soja

Family

bHLH

Protein Properties

Length: 166aa MW: 19585 Da PI: 9.9229

Description

bHLH family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Glyma.U015500.1.p	genome	JGI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	HLH	11.7	0.0005	17	56	5	55
HHHHHHHHHHHHHHHHHHHHCTSCCC...TTS-STCHHHHHHHHHHHHHHH CS HLH 5 hnerErrRRdriNsafeeLrellPkaskapskKlsKaeiLekAveYIksLq 55 + e+ErrRR+++ +++ Lr+l+ k a+i+e A+ YI q Glyma.U015500.1.p 17 NLEVERRRREKLSTRLLMLRSLMNK-----------ATIVEDAITYIETQQ 56 6699****************99755...........589999999997665 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SuperFamily	SSF47459	2.49E-10	14	72	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
CDD	cd00083	5.27E-7	14	60	No hit	No description
Gene3D	G3DSA:4.10.280.10	2.5E-6	14	77	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
SMART	SM00353	8.2E-5	18	61	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0046983	Molecular Function	protein dimerization activity

Sequence ? help Back to Top
Protein Sequence Length: 166 aa Download sequence Send to blast
MRKKNYECDT QVFKSKNLEV ERRRREKLST RLLMLRSLMN KATIVEDAIT YIETQQNIVQ 60 SLSYELHEME ATSEEIKPKK EEIDEEVQAT KIDGNKLWVK MIIEKKRGRF KKLMEAMHNI 120 GIELIDTNVT TLKKSYMVTT FMQLFFKAWM VNGKQKVVMD IVWGN*

Nucleic Localization Signal ? help Back to Top

No.	Start	End	Sequence
1	20	25	ERRRRE
2	21	26	RRRREK

Expression -- Description ? help Back to Top
Source	Description
Uniprot	DEVELOPMENTAL STAGE: First observed in floral meristem and early anther primordia. Later detected in archesporial cells. From stage 4 to early stage 5, weakly expressed in precursors of the middle layer, tapetum and meiocytes. Strongly expressed in the tapetum from late anther stage 5 to early stage 6, and at a lower level in meiocytes. {ECO:0000269\|PubMed:16831835}.
Uniprot	TISSUE SPECIFICITY: Mostly expressed in anthers, and, to a lower extent, in young inflorescences undergoing meiosis and siliques. {ECO:0000269\|PubMed:16831835}.

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription factor. Involved in the control of tapetum development. Required for male fertility and pollen differentiation, especially during callose deposition. {ECO:0000269\|PubMed:16831835}.

Cis-element ? help Back to Top
Source	Link
PlantRegMap	Glyma.U015500.1.p

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	AC185959	2e-49	AC185959.13 Glycine max cultivar Williams 82 clone gmw1-58k3, complete sequence.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_027348379.1	1e-66	transcription factor DYT1-like
Swissprot	O81900	6e-29	DYT1_ARATH; Transcription factor DYT1
TrEMBL	A0A445I211	1e-116	A0A445I211_GLYSO; Transcription factor DYT1
STRING	XP_007148286.1	2e-58	(Phaseolus vulgaris)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Fabids	OGEF5510	29	48
Representative plant	OGRP10309	4	8

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT4G21330.1	7e-20	bHLH family protein

Link Out ? help Back to Top
Phytozome	Glyma.U015500.1.p

Publications ? help Back to Top
Skinner MK,Rawls A,Wilson-Rawls J,Roalson EH Basic helix-loop-helix transcription factor gene family phylogenetics and nomenclature. Differentiation, 2010. 80(1): p. 1-8 [PMID:20219281] Jiang J,Zhang Z,Cao J Pollen wall development: the associated enzymes and metabolic pathways. Plant Biol (Stuttg), 2013. 15(2): p. 249-63 [PMID:23252839] Qian H, et al. Trace concentrations of imazethapyr (IM) affect floral organs development and reproduction in Arabidopsis thaliana: IM-induced inhibition of key genes regulating anther and pollen biosynthesis. Ecotoxicology, 2015. 24(1): p. 163-71 [PMID:25348600] Shumin Z, et al. One novel cis-element is essential for correct DYSFUNCTIONAL TAPETUM 1 (DYT1) expression in Arabidopsis thaliana. Plant Cell Rep., 2015. 34(10): p. 1773-80 [PMID:26134855] Cui J, et al. Feedback Regulation of DYT1 by Interactions with Downstream bHLH Factors Promotes DYT1 Nuclear Localization and Anther Development. Plant Cell, 2016. 28(5): p. 1078-93 [PMID:27113773] Arkadir D, et al. DYT1 dystonia increases risk taking in humans. Elife, 2017. [PMID:27249418] Premi E, et al. Functional Connectivity Networks in Asymptomatic and Symptomatic DYT1 Carriers. Mov. Disord., 2016. 31(11): p. 1739-1743 [PMID:27453152] Beauvais G, et al. Disruption of Protein Processing in the Endoplasmic Reticulum of DYT1 Knock-in Mice Implicates Novel Pathways in Dystonia Pathogenesis. J. Neurosci., 2016. 36(40): p. 10245-10256 [PMID:27707963] Richter F,Gerstenberger J,Bauer A,Liang CC,Richter A Sensorimotor tests unmask a phenotype in the DYT1 knock-in mouse model of dystonia. Behav. Brain Res., 2017. 317: p. 536-541 [PMID:27769743] Zhou S, et al. Function Identification of the Nucleotides in Key cis-Element of DYSFUNCTIONAL TAPETUM1 (DYT1) Promoter. Front Plant Sci, 2017. 8: p. 153 [PMID:28261229] Li DD,Xue JS,Zhu J,Yang ZN Gene Regulatory Network for Tapetum Development in Arabidopsis thaliana. Front Plant Sci, 2017. 8: p. 1559 [PMID:28955355] Ponterio G, et al. Enhanced mu opioid receptor-dependent opioidergic modulation of striatal cholinergic transmission in DYT1 dystonia. Mov. Disord., 2018. 33(2): p. 310-320 [PMID:29150865] György B, et al. Mutant torsinA in the heterozygous DYT1 state compromises HSV propagation in infected neurons and fibroblasts. Sci Rep, 2018. 8(1): p. 2324 [PMID:29396398]