PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Gorai.006G027400.2
Common NameB456_006G027400
Organism
Gossypium raimondii
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Malvales; Malvaceae; Malvoideae; Gossypium
Family E2F/DP
Protein Properties Length: 335aa    MW: 37948.8 Da    PI: 9.6348
Description E2F/DP family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Gorai.006G027400.2genomeJGIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1E2F_TDP74.79.4e-241984171
             E2F_TDP  1 rkeksLrlltqkflkllekseegivtlnevakeLvsedvknkrRRiYDilNVLealnliekkekneirwkg 71
                        rkeksL+ll+++fl+l+++ + +++ l+++a++L    v  +rRRiYD++N+Le+++++++k kn++ wkg
  Gorai.006G027400.2 19 RKEKSLGLLCSNFLALYNHDSVQTIGLDDAASKL---GV--ERRRIYDVVNILESIGVVARKGKNQYLWKG 84
                        79*****************999************...**..****************************98 PP
2E2F_TDP42.97.8e-141421933771
             E2F_TDP  37 e............dvknkrRRiYDilNVLealnliek.....kekneirwkg 71 
                                       v++k+RR+YDi+NV++++nliek     ++k+++rw g
  Gorai.006G027400.2 142 TaiallgdvhnstAVRTKVRRLYDIANVFSSMNLIEKthhpeSRKPAFRWLG 193
                         033333346666699**********************9999999******87 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:1.10.10.104.0E-251785IPR011991Winged helix-turn-helix DNA-binding domain
SuperFamilySSF467851.86E-161982IPR011991Winged helix-turn-helix DNA-binding domain
SMARTSM013721.3E-291984IPR003316E2F/DP family, winged-helix DNA-binding domain
PfamPF023193.5E-202084IPR003316E2F/DP family, winged-helix DNA-binding domain
SMARTSM013726.3E-13108193IPR003316E2F/DP family, winged-helix DNA-binding domain
PfamPF023193.6E-11130193IPR003316E2F/DP family, winged-helix DNA-binding domain
Gene3DG3DSA:1.10.10.105.1E-13138194IPR011991Winged helix-turn-helix DNA-binding domain
SuperFamilySSF467851.02E-8150194IPR011991Winged helix-turn-helix DNA-binding domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0005634Cellular Componentnucleus
GO:0005667Cellular Componenttranscription factor complex
GO:0005737Cellular Componentcytoplasm
GO:0003677Molecular FunctionDNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 335 aa     Download sequence    Send to blast
MSSFASQESE SNSRTLYCRK EKSLGLLCSN FLALYNHDSV QTIGLDDAAS KLGVERRRIY  60
DVVNILESIG VVARKGKNQY LWKGFGEIPK ALEKLKEEAL KQNFCFSDCS KSLRVLDENE  120
SADSSYVKNE GQDNLSESSK RTAIALLGDV HNSTAVRTKV RRLYDIANVF SSMNLIEKTH  180
HPESRKPAFR WLGWGAKLHN GSTTALELNE SKKRTFGTEI TNQNLKRTKA NSSIHRKLNQ  240
KENTGMHIKL DSVEHDHKMQ QHSKQCSKGF AFGPFTPAAI SSGNRNVRPI RDWESLASIY  300
KPQYLNQALS DLFAHYMEAW NSWYAEVARK EEIH*
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
4yo2_A5e-22191854228Transcription factor E2F8
Search in ModeBase
Expression -- Description ? help Back to Top
Source Description
UniprotDEVELOPMENTAL STAGE: Expressed in a cell cycle-dependent manner. Most abundant in mid-S phase. {ECO:0000269|PubMed:11786543, ECO:0000269|PubMed:15308755}.
UniprotTISSUE SPECIFICITY: High expression in young cotyledons and leaves, hypocotyls, shoot apical meristem, roots and mature pollen grains, moderate in developing trichomes, flowers and at early stages of developing anthers, and barely detectable in mature leaves. Not detected in primary root meristem, emerging lateral roots, pistils, developing embryos and siliques. {ECO:0000269|PubMed:11867638, ECO:0000269|PubMed:15308755}.
Functional Description ? help Back to Top
Source Description
UniProtInhibitor of E2F-dependent activation of gene expression. Binds specifically the E2 recognition site without interacting with DP proteins and prevents transcription activation by E2F/DP heterodimers. Does not bind retinoblastoma-related proteins. Acts as a growth regulator but is not associated with changes in the expression of cell cycle marker genes or in nuclear ploidy levels. Has no effect on cell proliferation, but may repress cell wall biosynthesis genes during cell elongation in differentiated cells. {ECO:0000269|PubMed:11786543, ECO:0000269|PubMed:11867638, ECO:0000269|PubMed:15308755}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_017610794.10.0PREDICTED: E2F transcription factor-like E2FF isoform X3
SwissprotQ8RWL06e-95E2FF_ARATH; E2F transcription factor-like E2FF
TrEMBLA0A0D2RW550.0A0A0D2RW55_GOSRA; Uncharacterized protein
STRINGGorai.006G027400.10.0(Gossypium raimondii)
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT3G01330.12e-88DP-E2F-like protein 3
Publications ? help Back to Top
  1. Dohmann EM, et al.
    The Arabidopsis COP9 signalosome is essential for G2 phase progression and genomic stability.
    Development, 2008. 135(11): p. 2013-22
    [PMID:18434413]
  2. Paterson AH, et al.
    Repeated polyploidization of Gossypium genomes and the evolution of spinnable cotton fibres.
    Nature, 2012. 492(7429): p. 423-7
    [PMID:23257886]