PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

Gorai.006G082300.3

Common Name

B456_006G082300

Organism

Gossypium raimondii

Taxonomic ID

29730

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Malvales; Malvaceae; Malvoideae; Gossypium

Family

MYB_related

Protein Properties

Length: 497aa MW: 55707.4 Da PI: 6.3397

Description

MYB_related family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Gorai.006G082300.3	genome	JGI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	Myb_DNA-binding	34.6	4.3e-11	108	149	4	46
S-HHHHHHHHHHHHHTTTT-HHHHHHHHTTTS-HHHHHHHHHH CS Myb_DNA-binding 4 WTteEdellvdavkqlGggtWktIartmgkgRtlkqcksrwqk 46 W ++++ ll+++++++G g+W+ +a+++g +++ + c++++ + Gorai.006G082300.3 108 WNADDEILLLEGIEMYGLGNWAEVAEHVG-TKSKEKCIDHYTN 149 ***************************.*********88 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
PIRSF	PIRSF025024	1.2E-136	35	494	IPR016827	Transcriptional adaptor 2
SMART	SM00291	1.6E-11	44	89	IPR000433	Zinc finger, ZZ-type
PROSITE profile	PS50135	10.981	44	91	IPR000433	Zinc finger, ZZ-type
Pfam	PF00569	5.9E-10	47	88	IPR000433	Zinc finger, ZZ-type
SuperFamily	SSF57850	3.53E-13	48	110	No hit	No description
CDD	cd02335	4.32E-25	48	96	No hit	No description
PROSITE pattern	PS01357	0	50	77	IPR000433	Zinc finger, ZZ-type
SuperFamily	SSF46689	3.9E-12	101	154	IPR009057	Homeodomain-like
PROSITE profile	PS51293	20.569	103	155	IPR017884	SANT domain
SMART	SM00717	5.4E-11	104	153	IPR001005	SANT/Myb domain
Pfam	PF00249	6.9E-11	107	149	IPR001005	SANT/Myb domain
CDD	cd00167	5.98E-11	108	150	No hit	No description
Gene3D	G3DSA:1.10.10.60	7.4E-7	108	150	IPR009057	Homeodomain-like

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006357	Biological Process	regulation of transcription from RNA polymerase II promoter
GO:0009631	Biological Process	cold acclimation
GO:0009733	Biological Process	response to auxin
GO:0009735	Biological Process	response to cytokinin
GO:0016573	Biological Process	histone acetylation
GO:0042127	Biological Process	regulation of cell proliferation
GO:0005634	Cellular Component	nucleus
GO:0003677	Molecular Function	DNA binding
GO:0003713	Molecular Function	transcription coactivator activity
GO:0005515	Molecular Function	protein binding
GO:0008270	Molecular Function	zinc ion binding

Sequence ? help Back to Top
Protein Sequence Length: 497 aa Download sequence Send to blast
MGRSRGNFHS ADEDPTQRSR RKKNASAGEN LESSSSGQGT SEGKRALYHC NYCNKDITGK 60 IRIKCAICPD FDLCIECFSV GAEVSPHKSC HLYRVMDNLS FPLICPDWNA DDEILLLEGI 120 EMYGLGNWAE VAEHVGTKSK EKCIDHYTNV YMKSPFFPLP DMSHVVGKNR KELLAMAKGH 180 TEDKKGTMLG ELSVKEESPF SPSRVKVEGS NCGRIMSGLN ADVESGARSS SNSTASATVV 240 KVSNMNQVKD GNVKMEDHQI DRNYGGKKPN SSGNEGPSLV ELSGYNAKRQ EFDPEYDNDA 300 EQLLAEMEFK DTDTEEEREL KLRVLRIYSK RLDERKRRKD FILERNLLYP NPIEKDLSPE 360 ERALCRRYDV FMRFHSKEEH DELLQTVIAE HRTLKRIEEL KEARAAGCRT SAEADRYLEQ 420 KRKREAEESS HRAKDGVQGG PGGQAAPNSF MASESVGKDS NARPTAQASS SYAKDLDIMG 480 FAETQLLSET VRMLYP*

Sequence ? help Back to Top

Protein Sequence Length: 497 aa Download sequence Send to blast

MGRSRGNFHS ADEDPTQRSR RKKNASAGEN LESSSSGQGT SEGKRALYHC NYCNKDITGK  60
IRIKCAICPD FDLCIECFSV GAEVSPHKSC HLYRVMDNLS FPLICPDWNA DDEILLLEGI  120
EMYGLGNWAE VAEHVGTKSK EKCIDHYTNV YMKSPFFPLP DMSHVVGKNR KELLAMAKGH  180
TEDKKGTMLG ELSVKEESPF SPSRVKVEGS NCGRIMSGLN ADVESGARSS SNSTASATVV  240
KVSNMNQVKD GNVKMEDHQI DRNYGGKKPN SSGNEGPSLV ELSGYNAKRQ EFDPEYDNDA  300
EQLLAEMEFK DTDTEEEREL KLRVLRIYSK RLDERKRRKD FILERNLLYP NPIEKDLSPE  360
ERALCRRYDV FMRFHSKEEH DELLQTVIAE HRTLKRIEEL KEARAAGCRT SAEADRYLEQ  420
KRKREAEESS HRAKDGVQGG PGGQAAPNSF MASESVGKDS NARPTAQASS SYAKDLDIMG  480
FAETQLLSET VRMLYP*

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
6cw2_C	8e-41	48	163	5	120	Transcriptional adapter 2
6cw3_E	1e-40	48	163	5	120	Transcriptional adapter 2
6cw3_G	1e-40	48	163	5	120	Transcriptional adapter 2
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Nucleic Localization Signal ? help Back to Top

No.	Start	End	Sequence
1	334	339	RKRRKD

Expression -- Description ? help Back to Top
Source	Description
Uniprot	TISSUE SPECIFICITY: Expressed in roots, leaves, stems, flowers and siliques, with the strongest activity in the meristematic zones. {ECO:0000269\|PubMed:11266554, ECO:0000269\|PubMed:12747832}.

Functional Description ? help Back to Top
Source	Description
UniProt	Required for the function of some acidic activation domains, which activate transcription from a distant site. The exact mechanism of action is not yet known (By similarity). ADA2 stimulates the acetyltransferase activity of GCN5 on free histones or nucleosomes, probably by opening up the promoter region. Mediates auxin and cytokinin signals in the control of cell proliferation and might be involved in repression of a freezing tolerance pathway at warm temperature (PubMed:12615937, PubMed:12747832). Involved in the positive regulation of salt-induced gene expression by maintaining locus-specific acetylation of histones H4 and H3 (PubMed:21193996). {ECO:0000250, ECO:0000269\|PubMed:12615937, ECO:0000269\|PubMed:12747832, ECO:0000269\|PubMed:21193996}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_012484629.1	0.0	PREDICTED: transcriptional adapter ADA2b
Swissprot	Q9ATB4	0.0	TAD2B_ARATH; Transcriptional adapter ADA2b
TrEMBL	A0A0D2RS40	0.0	A0A0D2RS40_GOSRA; Transcriptional adapter
STRING	Gorai.006G082300.1	0.0	(Gossypium raimondii)

Link Out ? help Back to Top
Phytozome	Gorai.006G082300.3

Publications ? help Back to Top
Vlachonasios KE,Thomashow MF,Triezenberg SJ Disruption mutations of ADA2b and GCN5 transcriptional adaptor genes dramatically affect Arabidopsis growth, development, and gene expression. Plant Cell, 2003. 15(3): p. 626-38 [PMID:12615937] Sieberer T,Hauser MT,Seifert GJ,Luschnig C PROPORZ1, a putative Arabidopsis transcriptional adaptor protein, mediates auxin and cytokinin signals in the control of cell proliferation. Curr. Biol., 2003. 13(10): p. 837-42 [PMID:12747832] Kerschen A,Napoli CA,Jorgensen RA,Müller AE Effectiveness of RNA interference in transgenic plants. FEBS Lett., 2004. 566(1-3): p. 223-8 [PMID:15147899] Hark AT, et al. Two Arabidopsis orthologs of the transcriptional coactivator ADA2 have distinct biological functions. Biochim. Biophys. Acta, 2009. 1789(2): p. 117-24 [PMID:18929690] Anzola JM, et al. Putative Arabidopsis transcriptional adaptor protein (PROPORZ1) is required to modulate histone acetylation in response to auxin. Proc. Natl. Acad. Sci. U.S.A., 2010. 107(22): p. 10308-13 [PMID:20479223] Kaldis A,Tsementzi D,Tanriverdi O,Vlachonasios KE Arabidopsis thaliana transcriptional co-activators ADA2b and SGF29a are implicated in salt stress responses. Planta, 2011. 233(4): p. 749-62 [PMID:21193996] Vlachonasios KE,Kaldis A,Nikoloudi A,Tsementzi D The role of transcriptional coactivator ADA2b in Arabidopsis abiotic stress responses. Plant Signal Behav, 2011. 6(10): p. 1475-8 [PMID:21897124] Heyndrickx KS,Vandepoele K Systematic identification of functional plant modules through the integration of complementary data sources. Plant Physiol., 2012. 159(3): p. 884-901 [PMID:22589469] Paterson AH, et al. Repeated polyploidization of Gossypium genomes and the evolution of spinnable cotton fibres. Nature, 2012. 492(7429): p. 423-7 [PMID:23257886] Kazama D,Kurusu T,Mitsuda N,Ohme-Takagi M,Tada Y Involvement of elevated proline accumulation in enhanced osmotic stress tolerance in Arabidopsis conferred by chimeric repressor gene silencing technology. Plant Signal Behav, 2014. 9(3): p. e28211 [PMID:24614501] Kim JY,Oh JE,Noh YS,Noh B Epigenetic control of juvenile-to-adult phase transition by the Arabidopsis SAGA-like complex. Plant J., 2015. 83(3): p. 537-45 [PMID:26095998] Kazama D, et al. Identification of Chimeric Repressors that Confer Salt and Osmotic Stress Tolerance in Arabidopsis. Plants (Basel), 2013. 2(4): p. 769-85 [PMID:27137403] Simon MK,Skinner DJ,Gallagher TL,Gasser CS Integument Development in Arabidopsis Depends on Interaction of YABBY Protein INNER NO OUTER with Coactivators and Corepressors. Genetics, 2017. 207(4): p. 1489-1500 [PMID:28971961] Lai J, et al. The Transcriptional Coactivator ADA2b Recruits a Structural Maintenance Protein to Double-Strand Breaks during DNA Repair in Plants. Plant Physiol., 2018. 176(4): p. 2613-2622 [PMID:29463775] Kotak J, et al. The histone acetyltransferase GCN5 and the transcriptional coactivator ADA2b affect leaf development and trichome morphogenesis in Arabidopsis. Planta, 2018. 248(3): p. 613-628 [PMID:29846775]