PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID HL.SW.v1.0.G002829.1
Organism
Humulus lupulus
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Rosales; Cannabaceae; Humulus
Family MYB
Protein Properties Length: 111aa    MW: 12248.9 Da    PI: 9.3148
Description MYB family protein
Gene Model
Gene Model ID Type Source Coding Sequence
HL.SW.v1.0.G002829.1genomeHOPBASEView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1Myb_DNA-binding58.81.2e-182875148
                          TSSS-HHHHHHHHHHHHHTTTT-HHHHHHHHTTTS-HHHHHHHHHHHT CS
       Myb_DNA-binding  1 rgrWTteEdellvdavkqlGggtWktIartmgkgRtlkqcksrwqkyl 48
                          +g+WTt Ed +lv++v+++G g+W+++ +  g+ R++k+c++rw ++l
  HL.SW.v1.0.G002829.1 28 KGPWTTSEDAILVEYVRKHGEGNWNAVQKNSGLARCGKSCRLRWANHL 75
                          79******************************************9996 PP
2Myb_DNA-binding25.23.9e-0881109130
                           TSSS-HHHHHHHHHHHHHTTTT-HHHHHHH CS
       Myb_DNA-binding   1 rgrWTteEdellvdavkqlGggtWktIart 30 
                           +g++++eE+ ++++++++lG++ W++ a+ 
  HL.SW.v1.0.G002829.1  81 KGSFSPEEERIIIELHAKLGNK-WARMASQ 109
                           799*******************.**99975 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PROSITE profilePS5129422.072379IPR017930Myb domain
Gene3DG3DSA:1.10.10.608.5E-242578IPR009057Homeodomain-like
SMARTSM007174.2E-142777IPR001005SANT/Myb domain
PfamPF002499.3E-172875IPR001005SANT/Myb domain
SuperFamilySSF466896.47E-2629105IPR009057Homeodomain-like
CDDcd001672.30E-113075No hitNo description
Gene3DG3DSA:1.10.10.605.8E-1479109IPR009057Homeodomain-like
SMARTSM007178580110IPR001005SANT/Myb domain
PROSITE profilePS5129412.27280110IPR017930Myb domain
PfamPF002493.3E-781109IPR001005SANT/Myb domain
CDDcd001670.0037483110No hitNo description
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0003677Molecular FunctionDNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 111 aa     Download sequence    Send to blast
MMMNDETVEE RAAAEEDAGG SRGGGLKKGP WTTSEDAILV EYVRKHGEGN WNAVQKNSGL  60
ARCGKSCRLR WANHLRPNLK KGSFSPEEER IIIELHAKLG NKWARMASQV *
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1a5j_A5e-2226107585B-MYB
1h8a_C7e-222610725105MYB TRANSFORMING PROTEIN
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtTranscription activator (PubMed:24278028, PubMed:25268707). Binds to 5'-CAACTGTC-3' and/or 5'-TAACAAA-3' motif in target gene promoter (e.g. alpha-amylase) to promote their expression (PubMed:11743113). Positive regulator of abscisic acid (ABA) responses leading to growth arrest during seed germination (PubMed:17217461). Promotes the expression of aleurone-related genes (e.g. CP1, CP, GASA1, BXL1 and BXL2) in seeds. Together with MYB33 and MYB65, promotes the programmed cell death (PCD) leading to vacuolation of protein storage vacuoles (PSVs) in the aleurone layers during seed germination (PubMed:20699403). Maybe involved in the regulation of leaves lamina morphogenesis (PubMed:25268707). Involved in pollen grain development (PubMed:22101548). Together with MYB97 and MYB120, functions as a male factor that controls pollen tube-synergid interaction in fertilization. Required for pollen tube growth arrest and sperm cell release in the female gametophyte, probably via the regulation of pollen tube-specific gene expression (PubMed:24278028, PubMed:23791732). {ECO:0000269|PubMed:11743113, ECO:0000269|PubMed:17217461, ECO:0000269|PubMed:20699403, ECO:0000269|PubMed:22101548, ECO:0000269|PubMed:23791732, ECO:0000269|PubMed:24278028, ECO:0000269|PubMed:25268707}.
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Repressed in germinating seeds by microRNA159 (miR159)-mediated cleavage in an abscisic acid (ABA) and ABI3-dependent manner, probably to desensitize hormone signaling during seedling stress responses (PubMed:15226253, PubMed:17217461). Induced by increased upon gibberellic acid (GA) treatment (PubMed:20699403). {ECO:0000269|PubMed:15226253, ECO:0000269|PubMed:17217461, ECO:0000269|PubMed:20699403}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_012089881.13e-53transcription factor MYB101
RefseqXP_013626947.12e-53PREDICTED: transcription factor GAMYB-like
RefseqXP_022554711.12e-53transcription factor MYB101-like
SwissprotO808831e-53MB101_ARATH; Transcription factor MYB101
TrEMBLA0A2P5D6212e-58A0A2P5D621_PARAD; MYB transcription factor
STRINGBo3g026690.18e-53(Brassica oleracea)
STRINGXP_008379641.12e-52(Malus domestica)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
FabidsOGEF3134817
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT2G32460.23e-51myb domain protein 101
Publications ? help Back to Top
  1. Zheng Z, et al.
    Target RNA Secondary Structure Is a Major Determinant of miR159 Efficacy.
    Plant Physiol., 2017. 174(3): p. 1764-1778
    [PMID:28515145]
  2. Xue T,Liu Z,Dai X,Xiang F
    Primary root growth in Arabidopsis thaliana is inhibited by the miR159 mediated repression of MYB33, MYB65 and MYB101.
    Plant Sci., 2017. 262: p. 182-189
    [PMID:28716415]