PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID HL.SW.v1.0.G019443.1
Organism
Humulus lupulus
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Rosales; Cannabaceae; Humulus
Family MYB
Protein Properties Length: 583aa    MW: 63796.3 Da    PI: 7.4693
Description MYB family protein
Gene Model
Gene Model ID Type Source Coding Sequence
HL.SW.v1.0.G019443.1genomeHOPBASEView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1Myb_DNA-binding482.8e-1580126148
                           TSSS-HHHHHHHHHHHHHTTTT-HHHHHHHHTTTS-HHHHHHHHHHHT CS
       Myb_DNA-binding   1 rgrWTteEdellvdavkqlGggtWktIartmgkgRtlkqcksrwqkyl 48 
                           +g WT++Ede l  av+ + g++Wk+Ia+ ++  R++ qc +rwqk+l
  HL.SW.v1.0.G019443.1  80 KGGWTPQEDETLRSAVAAFNGKSWKKIAEFFN-DRSEVQCLHRWQKVL 126
                           688*****************************.************986 PP
2Myb_DNA-binding60.53.7e-19132178148
                           TSSS-HHHHHHHHHHHHHTTTT-HHHHHHHHTTTS-HHHHHHHHHHHT CS
       Myb_DNA-binding   1 rgrWTteEdellvdavkqlGggtWktIartmgkgRtlkqcksrwqkyl 48 
                           +g+WT+eEd+++ ++v ++G   W++Iar ++ gR +kqc++rw+++l
  HL.SW.v1.0.G019443.1 132 KGPWTPEEDKKITELVSKYGATKWSLIARSLP-GRIGKQCRERWHNHL 178
                           79******************************.*************97 PP
3Myb_DNA-binding52.51.2e-16184227146
                           TSSS-HHHHHHHHHHHHHTTTT-HHHHHHHHTTTS-HHHHHHHHHH CS
       Myb_DNA-binding   1 rgrWTteEdellvdavkqlGggtWktIartmgkgRtlkqcksrwqk 46 
                           +++WT +E++ l +a++ +G++ W+ Ia+ ++ gRt++ +k++w++
  HL.SW.v1.0.G019443.1 184 KDAWTSDEELSLMHAHQIHGNK-WAEIAKVLP-GRTDNAIKNHWNS 227
                           679*******************.*********.***********96 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PROSITE profilePS5129412.94775126IPR017930Myb domain
SMARTSM007175.5E-1379128IPR001005SANT/Myb domain
PfamPF002493.2E-1480126IPR001005SANT/Myb domain
SuperFamilySSF466892.23E-1481136IPR009057Homeodomain-like
Gene3DG3DSA:1.10.10.604.1E-1782134IPR009057Homeodomain-like
CDDcd001672.57E-1183126No hitNo description
PROSITE profilePS5129431.279127182IPR017930Myb domain
SuperFamilySSF466891.61E-31129225IPR009057Homeodomain-like
SMARTSM007171.1E-17131180IPR001005SANT/Myb domain
PfamPF002495.8E-18132178IPR001005SANT/Myb domain
CDDcd001677.60E-16134178No hitNo description
Gene3DG3DSA:1.10.10.601.6E-27135185IPR009057Homeodomain-like
PROSITE profilePS5129420.949183233IPR017930Myb domain
SMARTSM007172.2E-14183231IPR001005SANT/Myb domain
PfamPF002495.9E-15184227IPR001005SANT/Myb domain
CDDcd001673.57E-11186229No hitNo description
Gene3DG3DSA:1.10.10.608.5E-23186233IPR009057Homeodomain-like
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0003677Molecular FunctionDNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 583 aa     Download sequence    Send to blast
MSFSSIPATL SPEEQKEMSE VKLEECCLEN KQSTAASSSS VSEGSGSVFL KSPGVCSPAA  60
STSPPQWYYP RTSGPVRRAK GGWTPQEDET LRSAVAAFNG KSWKKIAEFF NDRSEVQCLH  120
RWQKVLNPEL VKGPWTPEED KKITELVSKY GATKWSLIAR SLPGRIGKQC RERWHNHLNP  180
DIRKDAWTSD EELSLMHAHQ IHGNKWAEIA KVLPGRTDNA IKNHWNSSLK KKLDFFVSTG  240
SLPPATKNNS QNGPKDTNKC SATKKSLVCS NKEFDSTAHT LGNATMYTIN EDGNNQLDSS  300
GVLCSMLGSS SAPPNESADS EGIESKPVSS SMDPSYSNSD SVVKFENGGI NREANIENCL  360
ISKQSQHCGI NNEENGEVKE DKVVGTPLSS KTLFFGSLCY EPPQLDACIP LDSDFSSIHC  420
LQNEFNSSTY SSPGSCFTPP CVKGHGFTLP SPESVLKMAA LTFPNTPSIL RKRKYKAQTP  480
LLPNEIEKAD HATQEHDVSK TNLEMPGSQD GSLCKSPTYH GINSAGPNGK AFNASPPYRL  540
RSKRTAVLKS VEKQLEFTFD KEEHEGNVKS VEFSAKTKMG VT*
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1h88_C2e-65792335159MYB PROTO-ONCOGENE PROTEIN
1h89_C2e-65792335159MYB PROTO-ONCOGENE PROTEIN
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtTranscription factor that binds 5'-AACGG-3' motifs in gene promoters (By similarity). Transcription repressor that regulates organ growth. Binds to the promoters of G2/M-specific genes and to E2F target genes to prevent their expression in post-mitotic cells and to restrict the time window of their expression in proliferating cells (PubMed:26069325). {ECO:0000250|UniProtKB:Q94FL9, ECO:0000269|PubMed:26069325}.
Binding Motif ? help Back to Top
Motif ID Method Source Motif file
MP00482DAPTransfer from AT5G02320Download
Motif logo
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Slightly induced by ethylene and salicylic acid (SA). {ECO:0000269|PubMed:16463103}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieveRetrieve
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_024031238.10.0transcription factor MYB3R-3 isoform X1
SwissprotQ6R0321e-154MB3R5_ARATH; Transcription factor MYB3R-5
TrEMBLA0A2P5DS500.0A0A2P5DS50_TREOI; GAMYB transcription factor
STRINGXP_010111464.10.0(Morus notabilis)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
FabidsOGEF66163449
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT5G02320.21e-145myb domain protein 3r-5
Publications ? help Back to Top
  1. Ding Y, et al.
    Four distinct types of dehydration stress memory genes in Arabidopsis thaliana.
    BMC Plant Biol., 2013. 13: p. 229
    [PMID:24377444]
  2. Kobayashi K, et al.
    Transcriptional repression by MYB3R proteins regulates plant organ growth.
    EMBO J., 2015. 34(15): p. 1992-2007
    [PMID:26069325]
  3. Chen P, et al.
    Arabidopsis R1R2R3-Myb proteins are essential for inhibiting cell division in response to DNA damage.
    Nat Commun, 2017. 8(1): p. 635
    [PMID:28935922]