PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID HL.SW.v1.0.G020283.1
Organism
Humulus lupulus
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Rosales; Cannabaceae; Humulus
Family E2F/DP
Protein Properties Length: 158aa    MW: 17837.8 Da    PI: 10.0225
Description E2F/DP family protein
Gene Model
Gene Model ID Type Source Coding Sequence
HL.SW.v1.0.G020283.1genomeHOPBASEView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1E2F_TDP702.9e-22588371
               E2F_TDP  3 eksLrlltqkflklleksee.givtlnevakeLvse...............dvknkrRRiYDilNVLealnliekkekneirwkg 71
                          +k+L      + ++++k e+ g++t+ eva+e+++e               d+kn+rRR+YD+lNVL+al++i++ +k+ei+wkg
  HL.SW.v1.0.G020283.1  5 RKGLARSLVVVYDICKKLETkGRTTYGEVADEIIAEfggtvkespvsldefDEKNIRRRVYDALNVLMALDIITR-DKKEIQWKG 88
                          56666655666789***9999******************************************************.*******98 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SMARTSM013721.1E-22388IPR003316E2F/DP family, winged-helix DNA-binding domain
SuperFamilySSF467854.9E-161689IPR011991Winged helix-turn-helix DNA-binding domain
Gene3DG3DSA:1.10.10.109.0E-321693IPR011991Winged helix-turn-helix DNA-binding domain
PfamPF023191.9E-181788IPR003316E2F/DP family, winged-helix DNA-binding domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0005667Cellular Componenttranscription factor complex
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 158 aa     Download sequence    Send to blast
MLRRRKGLAR SLVVVYDICK KLETKGRTTY GEVADEIIAE FGGTVKESPV SLDEFDEKNI  60
RRRVYDALNV LMALDIITRD KKEIQWKGLP TQDVKGLEEL KATRMKLVNR IGKKTAYLND  120
LKDQRAGQIT VHINALHSSS LQKNVLCVRH ACQLCAL*
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1cf7_B6e-2518951995PROTEIN (TRANSCRIPTION FACTOR DP-2)
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtInvolved in the regulation of the G1/S transition. Increases the DNA binding activity of E2F proteins after heterodimerization. The complex DPB/E2FC restricts cell division and lateral root initiation and may function as a negative regulator of E2F-regulated genes. The interaction with SKP2A is controlled by auxin. {ECO:0000269|PubMed:11891240, ECO:0000269|PubMed:16920782}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_024031258.14e-53transcription factor-like protein DPA isoform X1
RefseqXP_024031259.14e-53transcription factor-like protein DPA isoform X2
SwissprotQ9FNY21e-38DPB_ARATH; Transcription factor-like protein DPB
TrEMBLW9SWI65e-51W9SWI6_9ROSA; Transcription factor-like protein DPB
STRINGXP_010111484.18e-52(Morus notabilis)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
FabidsOGEF33213366
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT5G03415.16e-41Transcription factor DP