PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID HL.SW.v1.0.G022602.1
Organism
Humulus lupulus
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Rosales; Cannabaceae; Humulus
Family C2H2
Protein Properties Length: 185aa    MW: 21282.8 Da    PI: 10.3387
Description C2H2 family protein
Gene Model
Gene Model ID Type Source Coding Sequence
HL.SW.v1.0.G022602.1genomeHOPBASEView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1zf-C2H217.41.2e-057393323
                          ETTTTEEESSHHHHHHHHHHT CS
               zf-C2H2  3 CpdCgksFsrksnLkrHirtH 23
                          C++Cgk F r  nL+ H r H
  HL.SW.v1.0.G022602.1 73 CEICGKGFQRDQNLQLHRRGH 93
                          *******************88 PP
2zf-C2H215.26.4e-05147169123
                           EEETTTTEEESSHHHHHHHHHHT CS
               zf-C2H2   1 ykCpdCgksFsrksnLkrHirtH 23 
                           +kC++C+k++  +s+ k H +t+
  HL.SW.v1.0.G022602.1 147 WKCEKCSKRYAVQSDWKAHSKTC 169
                           58*****************9998 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:3.30.160.601.2E-57093IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
SuperFamilySSF576675.9E-77093No hitNo description
SMARTSM003550.0767193IPR015880Zinc finger, C2H2-like
PROSITE profilePS5015711.4897193IPR007087Zinc finger, C2H2
PROSITE patternPS0002807393IPR007087Zinc finger, C2H2
Gene3DG3DSA:3.30.160.604.7E-5135168IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
SuperFamilySSF576675.9E-7142167No hitNo description
SMARTSM00355130147167IPR015880Zinc finger, C2H2-like
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0003676Molecular Functionnucleic acid binding
GO:0046872Molecular Functionmetal ion binding
Sequence ? help Back to Top
Protein Sequence    Length: 185 aa     Download sequence    Send to blast
MAEDQTNIPN GFSQISPILE GSTIINPPPL KKKRNLPGTP GKLFFFFFMY IYPEAEVIAL  60
SPKTLMATNR FLCEICGKGF QRDQNLQLHR RGHNLPWKLK QRSSKEPKKR VYVCPEKTCV  120
HHHPSRALGD LTGIKKHFCR KHGEKKWKCE KCSKRYAVQS DWKAHSKTCG TREYKCDCGT  180
LFSR*
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
5b3h_C4e-23143184344Zinc finger protein JACKDAW
5b3h_F4e-23143184344Zinc finger protein JACKDAW
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtTranscription factor that regulates tissue boundaries and asymmetric cell division (PubMed:17785527, PubMed:25829440). Contributes to the sequestration of 'SHORT-ROOT' to the nucleus (PubMed:17785527, PubMed:25829440). Interacts with the SCR and MGP promoters (PubMed:21935722). Does not show transcription activity by itself, but regulates the transcription of downstream genes through interaction with other transcription factors (PubMed:21935722). Binds DNA via its zinc fingers (PubMed:24821766). Recognizes and binds to SCL3 promoter sequence 5'-AGACAA-3' to promotes its expression when in complex with RGA (PubMed:24821766). Positively involved in gibberellic acid (GA) signaling (PubMed:24821766). {ECO:0000269|PubMed:17785527, ECO:0000269|PubMed:21935722, ECO:0000269|PubMed:24821766, ECO:0000269|PubMed:25829440}.
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Up-regulated by the transcription factor JKD, and down-regulated by SHR, SCR and itself. {ECO:0000269|PubMed:21935722}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_002275400.31e-102PREDICTED: zinc finger protein MAGPIE
RefseqXP_028761654.11e-104zinc finger protein MAGPIE-like, partial
SwissprotQ9ZWA64e-98IDD3_ARATH; Zinc finger protein MAGPIE
TrEMBLA0A2P5FJ801e-115A0A2P5FJ80_TREOI; TFIIH C1-like domain containing protein
STRINGVIT_12s0028g03030.t011e-102(Vitis vinifera)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
FabidsOGEF18134275
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT1G03840.22e-93C2H2 family protein
Publications ? help Back to Top
  1. Muñoz-Strale D,León G
    Identification of two highly specific pollen promoters using transcriptomic data.
    Plant Physiol. Biochem., 2014. 83: p. 292-9
    [PMID:25208507]
  2. Moreno-Risueno MA, et al.
    Transcriptional control of tissue formation throughout root development.
    Science, 2015. 350(6259): p. 426-30
    [PMID:26494755]