PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID HL.SW.v1.0.G025924.1
Organism
Humulus lupulus
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Rosales; Cannabaceae; Humulus
Family MYB
Protein Properties Length: 316aa    MW: 34380.5 Da    PI: 7.6941
Description MYB family protein
Gene Model
Gene Model ID Type Source Coding Sequence
HL.SW.v1.0.G025924.1genomeHOPBASEView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1Myb_DNA-binding315.8e-101468348
                          SS-HHHHHHHHHHHHHTTTT..........-HHHHHHHHTTTS-HHHHHHHHHHHT CS
       Myb_DNA-binding  3 rWTteEdellvdavkqlGgg..........tWktIartmgkgRtlkqcksrwqkyl 48
                           W++eE++ + +a++ + +           +W + a++++ +++ +++k ++q++l
  HL.SW.v1.0.G025924.1 14 TWSKEEEKAFENAIAIHWSTtdqedeeseeQWQKMASMVP-TKSMEELKRHYQMLL 68
                          7***************************************.************986 PP
2Myb_DNA-binding38.82.1e-12147191347
                           SS-HHHHHHHHHHHHHTTTT-HHHHHHHHTTTS-HHHHHHHHHHH CS
       Myb_DNA-binding   3 rWTteEdellvdavkqlGggtWktIartmgkgRtlkqcksrwqky 47 
                           +WT+eE+ l++ +  ++G+g+W++I+r +   Rt+ q+ s+ qky
  HL.SW.v1.0.G025924.1 147 PWTEEEHRLFLLGLDKFGKGDWRSISRNFVISRTPTQVASHAQKY 191
                           7*****************************99************9 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PROSITE profilePS512937.3951070IPR017884SANT domain
SMARTSM007171.8E-71170IPR001005SANT/Myb domain
SuperFamilySSF466891.79E-71371IPR009057Homeodomain-like
PfamPF002493.1E-81368IPR001005SANT/Myb domain
Gene3DG3DSA:1.10.10.602.8E-41469IPR009057Homeodomain-like
CDDcd001677.01E-61768No hitNo description
PROSITE profilePS5129416.873140196IPR017930Myb domain
SuperFamilySSF466898.61E-17142197IPR009057Homeodomain-like
TIGRFAMsTIGR015574.5E-17144194IPR006447Myb domain, plants
SMARTSM007172.3E-10144194IPR001005SANT/Myb domain
Gene3DG3DSA:1.10.10.606.9E-11145190IPR009057Homeodomain-like
CDDcd001671.14E-9147192No hitNo description
PfamPF002497.9E-11147191IPR001005SANT/Myb domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0009651Biological Processresponse to salt stress
GO:0009733Biological Processresponse to auxin
GO:0009739Biological Processresponse to gibberellin
GO:0009751Biological Processresponse to salicylic acid
GO:0009753Biological Processresponse to jasmonic acid
GO:0046686Biological Processresponse to cadmium ion
GO:0003677Molecular FunctionDNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 316 aa     Download sequence    Send to blast
MSSTSTTTTD ITTTWSKEEE KAFENAIAIH WSTTDQEDEE SEEQWQKMAS MVPTKSMEEL  60
KRHYQMLLDD VTAIEDGRIP VPYYTVPADS SKTMMGKDNS HVVSGSEKRM SSGHGSSGFS  120
GLQGHDSGGH GGKGVSRAEQ ERRKGIPWTE EEHRLFLLGL DKFGKGDWRS ISRNFVISRT  180
PTQVASHAQK YFIRLNSVNR DRRRSSIHDI TSVTNGEVPP HQAPITGVQQ PNTNSPSIPA  240
IGAPPVKHRG QTHMPGMGMY GAPMGHPVAA AAAAAAGHMA SAVGTPVMLP RGHHHHPPPY  300
VVPVAYPMAP PTMHQ*
Functional Description ? help Back to Top
Source Description
UniProtTranscription activator that binds to 5'-TATCCA-3' elements in gene promoters. Derepresses strongly the sugar-repressed transcription of promoters containing SRS or 5'-TATCCA-3' elements. Functions with GAMYB to integrate diverse nutrient starvation and gibberellin (GA) signaling pathways during germination of grains. Sugar, nitrogen and phosphate starvation signals converge and interconnect with GA to promote the co-nuclear import of MYBS1 and GAMYB, resulting in the expression of a large set of GA-inducible hydrolases, transporters, and regulators that are essential for mobilization of nutrient reserves in the endosperm to support seedling growth (PubMed:22773748). {ECO:0000269|PubMed:12172034, ECO:0000269|PubMed:22773748}.
UniProtTranscription activator that binds to 5'-TATCCA-3' elements in gene promoters. Derepress strongly the sugar-repressed transcription of promoters containing SRS or 5'-TATCCA-3' elements. {ECO:0000250|UniProtKB:Q8LH59}.
Binding Motif ? help Back to Top
Motif ID Method Source Motif file
MP00191DAPTransfer from AT1G49010Download
Motif logo
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Repressed by sucrose and gibberellic acid (GA). {ECO:0000269|PubMed:12172034}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieveRetrieve
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_007036438.21e-140PREDICTED: transcription factor DIVARICATA
SwissprotB8A9B23e-80MYBS1_ORYSI; Transcription factor MYBS1
SwissprotQ8LH593e-80MYBS1_ORYSJ; Transcription factor MYBS1
TrEMBLA0A2P5CM271e-155A0A2P5CM27_PARAD; GAMYB transcription factor
STRINGEOY209391e-139(Theobroma cacao)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
FabidsOGEF106943340
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT1G49010.12e-58MYB family protein
Publications ? help Back to Top
  1. Hong YF, et al.
    Convergent starvation signals and hormone crosstalk in regulating nutrient mobilization upon germination in cereals.
    Plant Cell, 2012. 24(7): p. 2857-73
    [PMID:22773748]