PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Home  TFext  BLAST  Prediction  Download  Help  About  Links  PlantRegMap
(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID HL.SW.v1.0.G043799.1
Organism
Humulus lupulus
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Rosales; Cannabaceae; Humulus
Family NF-X1
Protein Properties Length: 1787aa    MW: 195121 Da    PI: 7.8309
Description NF-X1 family protein
Gene Model
Gene Model ID Type Source Coding Sequence
HL.SW.v1.0.G043799.1genomeHOPBASEView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1zf-NF-X121.16.7e-0710051023119
              zf-NF-X1    1 CGkHkCqklCHeGpCppCp 19  
                            CG+HkC+++CH GpC++C+
  HL.SW.v1.0.G043799.1 1005 CGRHKCEQICHVGPCDQCQ 1023
                            ******************6 PP
2zf-NF-X116.51.8e-0510691086118
              zf-NF-X1    1 CGkHkCqklCHeGpCppC 18  
                            CG+H C+++CH+G C++C
  HL.SW.v1.0.G043799.1 1069 CGNHFCGEICHPGSCGEC 1086
                            ****************** PP
3zf-NF-X117.41e-0512221240119
              zf-NF-X1    1 CGkHkCqklCHeGpCppCp 19  
                            CG+H C++lCH G CppC 
  HL.SW.v1.0.G043799.1 1222 CGQHACESLCHSGHCPPCL 1240
                            ******************6 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:1.10.275.102.4E-4477193IPR024083Fumarase/histidase, N-terminal
SuperFamilySSF485572.2E-9977522IPR008948L-Aspartase-like
TIGRFAMsTIGR009282.2E-11887525IPR004769Adenylosuccinate lyase
CDDcd01598098521No hitNo description
PfamPF002069.9E-56132390IPR022761Fumarate lyase, N-terminal
PRINTSPR001499.2E-13192210IPR000362Fumarate lyase family
Gene3DG3DSA:1.20.200.102.9E-85194464No hitNo description
PRINTSPR001499.2E-13238256IPR000362Fumarate lyase family
PRINTSPR001499.2E-13326353IPR000362Fumarate lyase family
PRINTSPR001499.2E-13369385IPR000362Fumarate lyase family
PROSITE patternPS001630369378IPR020557Fumarate lyase, conserved site
PfamPF083283.3E-50406520IPR013539Adenylosuccinate lyase PurB, C-terminal
Gene3DG3DSA:1.10.40.301.0E-31465520No hitNo description
PfamPF083281.6E-16533590IPR013539Adenylosuccinate lyase PurB, C-terminal
Gene3DG3DSA:1.10.40.304.5E-23533590No hitNo description
SuperFamilySSF578503.59E-7830897No hitNo description
PROSITE profilePS500168.751837897IPR019787Zinc finger, PHD-finger
PROSITE patternPS013590840894IPR019786Zinc finger, PHD-type, conserved site
PROSITE profilePS500899.362840895IPR001841Zinc finger, RING-type
CDDcd060083.11E-7928988No hitNo description
SMARTSM004380.023950968IPR000967Zinc finger, NF-X1-type
PfamPF0142214952967IPR000967Zinc finger, NF-X1-type
CDDcd060082.68E-149951043No hitNo description
SMARTSM004385.4E-410051024IPR000967Zinc finger, NF-X1-type
PfamPF014222.0E-510051022IPR000967Zinc finger, NF-X1-type
CDDcd060081.73E-1110591101No hitNo description
SMARTSM004384.8E-410691088IPR000967Zinc finger, NF-X1-type
PfamPF014220.009410691086IPR000967Zinc finger, NF-X1-type
CDDcd060082.18E-1511171165No hitNo description
SMARTSM004389.9E-511271146IPR000967Zinc finger, NF-X1-type
PfamPF014228.7E-411291144IPR000967Zinc finger, NF-X1-type
CDDcd060082.97E-411741233No hitNo description
SMARTSM0043812011841214IPR000967Zinc finger, NF-X1-type
PfamPF014223311841195IPR000967Zinc finger, NF-X1-type
CDDcd060084.90E-1012121255No hitNo description
SMARTSM004384.1E-412221241IPR000967Zinc finger, NF-X1-type
PfamPF014221.9E-412221239IPR000967Zinc finger, NF-X1-type
CDDcd060087.00E-812691317No hitNo description
SMARTSM004380.02612791297IPR000967Zinc finger, NF-X1-type
PfamPF014222512791296IPR000967Zinc finger, NF-X1-type
CDDcd060083.70E-413221380No hitNo description
SMARTSM004382.813321362IPR000967Zinc finger, NF-X1-type
PfamPF014220.1913321347IPR000967Zinc finger, NF-X1-type
CDDcd060087.73E-613601409No hitNo description
PfamPF014228913641382IPR000967Zinc finger, NF-X1-type
SMARTSM004380.5913711392IPR000967Zinc finger, NF-X1-type
Gene3DG3DSA:3.30.70.3301.1E-416081663IPR012677Nucleotide-binding alpha-beta plait domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006188Biological ProcessIMP biosynthetic process
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0009642Biological Processresponse to light intensity
GO:0009651Biological Processresponse to salt stress
GO:0009697Biological Processsalicylic acid biosynthetic process
GO:0010188Biological Processresponse to microbial phytotoxin
GO:0010310Biological Processregulation of hydrogen peroxide metabolic process
GO:0042742Biological Processdefense response to bacterium
GO:0005634Cellular Componentnucleus
GO:0000166Molecular Functionnucleotide binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
GO:0004018Molecular FunctionN6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming) activity
GO:0005515Molecular Functionprotein binding
GO:0008270Molecular Functionzinc ion binding
Sequence ? help Back to Top
Protein Sequence    Length: 1787 aa     Download sequence    Send to blast
MELGSSSLAL NTAHFSCFGS TPTKFLRPNE SSTLFLLPLS SNPSLSLARN PFRFKATLKE  60
FDIATQKTVK NMSRDLEYST LTALSPLDGR YWGKVKDLAP YMSEFALIYY RVLVEVQWLI  120
KLSEIPGVEE VPSFSNDARS FLQGIIDGFT VDDALEIKKI ERVTNHDVKA VEYFLKQKCQ  180
PHPEIAKVLE FFHFSCTSED INNLAHALML KEALDNTILP VVDDLIEAIG QMAKDNAHIS  240
MLSRTHGQPA SPTTLGKEMA IFAVRLSRER RDISQVEIMG KFAGAVGNYN AHLVAYPAIN  300
WAQIAEEFVT SLGLSFNAYV SQIETHDYMA KLFHAIYRLN NILIDFDRDI WGYISWGYFK  360
QTTKAGEIGS STMPHKVNPI DFENSEGNLG VANGTLSHLS TKLPISRFQR DLTDSTVLRN  420
MGVGLGHSLL AYKSTLQGIS KLQVNGARLS EDLDNCWEVL AEPIQTVMRR YGVPEPYEKL  480
KELTRGRAVN KESIREFIAG LELPNEAKTE LLKLTPHSYV GAAVELAITT EKAVKLVMRR  540
YGVPEPYEKL KELTRGRAVN KESIREFIAG LELPNEAKTE LLKLTPHSYV GAAVELAITT  600
EKAVKLVNGN ERRDRPRSTA QPSRREWVPR GPSTVTVVNQ PSSSHSNSTE NTNGGDSTLS  660
SAASHGRHKA NSSPHLNSAD NGNGSVPIHS SSASHSHSRY RGNNSSHSNS SENRNGGDLT  720
HNYAASHGRY KGIINLPSNS TENGNGGEPT HSSAVLHSQH RGNNNFHSNS SANGIGVDST  780
NSFAAAHGRY KGNYSSRGQV SRPVNNRREQ QERGSETKDS TLPQLVQEIQ EKLMKGAVEC  840
MICYDMVRRS APVWSCGSCY SIFHLNCIKK WARAPTSVDL SVDNQGFNWR CPGCQSVELT  900
SSKEIRYVCF CGKRPDPPSD LYLTPHSCGE PCGKPLERDV GRGGSKEDHC PHVCVLQCHP  960
GPCPPCKAFA PPRICSCGKK IITTRCSDRK SGLTCGQRCE KLLSCGRHKC EQICHVGPCD  1020
QCQVEVNAAC FCKKTVEAVL CADMTVKGVV KAEDGVFTCN SLCGKKLNCG NHFCGEICHP  1080
GSCGECELLP SKTKTCHCGK TVLKEERNSC LDPIPTCSKI CQKVLPCEKH SCEEVCHAGD  1140
CPPCLVKVSQ KCRCTSTSRT VECYKTTSDE KFTCDRACGR KKSCGRHRCN ERCCPLSNSS  1200
STYSEEWDPH VCSMSCGKKL RCGQHACESL CHSGHCPPCL ETIFTDLICA CGRTSIPPPL  1260
PCGTPPPSCQ LPCSVPQPCG HSASHSCHFG DCPPCSVPVA KECIGGHVVL RNIPCGSRDI  1320
RCNKLCGKTR QCGMHACGRT CHLPPCDAQT GSEPGLRSSC GQTCGAPRRD CRHTCTAPCH  1380
PSYLCPDTRC DFPVTITCLC GRISASVPCD AGGTNSGNYN ADTVYEASVM QKLPAQLQPV  1440
EATGIKIPLG QRKLMCEDEC AKLERKRVLA DAFDIATPNL EALHFGESSS VSELLGDLYR  1500
RDPKWVISVE ERCKFLVLGK SRGSTSGLKV HVFCPMLKEK RDAVRVIAER WKLAVNAAGW  1560
EPKRFIVVHV TPKSKVPPRI LGVKGTTTVS APQPPAFDPL VDMDPRLVVS FQDLPRDADI  1620
SALVLRFGGE CELVWLNDKN ALAVFHDPAR AATAMRRLDH GSVYTGAVLF HATAGASGST  1680
SGANAWGGAG TGTAKSNPWK KASVQEDTWG GDEWSSSGSA DVQPSAWKKE TPLAASLNRW  1740
SVLDNENSTS SMAAGSVVGN VSETETSEVA EDWEKAYDTS IEEEKN*
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
3gzh_A0.06052613477Adenylosuccinate lyase
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtMediates E2-dependent ubiquitination (By similarity). Confers resistance to osmotic stress such as high salinity. Promotes H(2)O(2) production. Negative regulator of some defense-related genes via an salicylic acid (SA)-dependent signaling pathway. Confers susceptibility to the compatible phytopathogen Pseudomonas syringae pv. tomato strain DC3000 (Pst DC3000). Mediates resistance to type A trichothecenes (phytotoxins produced by phytopathogenic fungi). {ECO:0000250, ECO:0000269|PubMed:16905136, ECO:0000269|PubMed:18069941, ECO:0000269|PubMed:19704430}.
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: By brassinosteroids, osmotic stress and high salinity. Accumulates in response to SA, ethylene, methyl jasmonate (MeJA), flagellin (e.g. flg22), and type A trichothecenes such as T-2 toxin and diacetoxyscirpenol (DAS), but not in response to type B trichothecenes such as deoxynivalenol (DON). {ECO:0000269|PubMed:16905136, ECO:0000269|PubMed:18069941, ECO:0000269|PubMed:19704430}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_010091735.10.0NF-X1-type zinc finger protein NFXL1
SwissprotQ9SY590.0NFXL1_ARATH; NF-X1-type zinc finger protein NFXL1
TrEMBLA0A2P5CHF90.0A0A2P5CHF9_PARAD; Zinc finger, FYVE/PHD-type
STRINGXP_010091735.10.0(Morus notabilis)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
FabidsOGEF69723145
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT1G10170.10.0NF-X-like 1