PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Han000454
Organism
Helianthus annuus
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; campanulids; Asterales; Asteraceae; Asteroideae; Heliantheae alliance; Heliantheae; Helianthus
Family bHLH
Protein Properties Length: 198aa    MW: 22314.4 Da    PI: 9.6994
Description bHLH family protein
Gene Model
Gene Model ID Type Source Coding Sequence
gnl|UG|Han#S18713662PU_unrefUnigeneView CDS
PUT-169a-Helianthus_annuus-56898PU_unrefplantGDBView CDS
PUT-169a-Helianthus_annuus-56899PU_refplantGDBView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1HLH41.52.3e-131459454
               HHHHHHHHHHHHHHHHHHHHHCTSCCC...TTS-STCHHHHHHHHHHHHHH CS
        HLH  4 ahnerErrRRdriNsafeeLrellPkaskapskKlsKaeiLekAveYIksL 54
               +h e+Er+RR+++N++f  Lr ++P+       K++Ka+ L  A+ YI++L
  Han000454 14 NHVEAERQRREKLNQKFYALRAVVPNV-----SKMDKASLLGDAIAYINDL 59
               799***********************6.....5****************98 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PROSITE profilePS5088816.9261059IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
SuperFamilySSF474591.24E-181379IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
CDDcd000831.13E-121364No hitNo description
PfamPF000107.7E-111459IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
Gene3DG3DSA:4.10.280.104.4E-191479IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
SMARTSM003533.6E-161665IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0046983Molecular Functionprotein dimerization activity
Sequence ? help Back to Top
Protein Sequence    Length: 198 aa     Download sequence    Send to blast
XALWPRNGRE EPLNHVEAER QRREKLNQKF YALRAVVPNV SKMDKASLLG DAIAYINDLK  60
LKLQTTETDK EELKAQLNGV KKELLTKDSR QSSSSAVSPL EDAKIANANA NANTNIKDLD  120
IDVKIIGWEA MIRVQCNRKN HPASRLMSAL KEMDLDLHHA SVSVVNELMM QQATVKMGSR  180
FYTQDQLRIA LTNKILGC
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
5gnj_A2e-36884278Transcription factor MYC2
5gnj_B2e-36884278Transcription factor MYC2
5gnj_E2e-36884278Transcription factor MYC2
5gnj_F2e-36884278Transcription factor MYC2
5gnj_G2e-36884278Transcription factor MYC2
5gnj_I2e-36884278Transcription factor MYC2
5gnj_M2e-36884278Transcription factor MYC2
5gnj_N2e-36884278Transcription factor MYC2
Search in ModeBase
Expression -- Description ? help Back to Top
Source Description
UniprotTISSUE SPECIFICITY: Highly expressed in trichomes and at lower levels in leaves and flowers (PubMed:24884371). Expressed at low levels in roots, stems, leaves, flowers and fruits (PubMed:15231736). {ECO:0000269|PubMed:15231736, ECO:0000269|PubMed:24884371}.
Functional Description ? help Back to Top
Source Description
UniProtTranscriptional activator that binds to the G-box motif (5'-AACGTG-3') found in a number of promoters of jasmonate-induced genes (PubMed:15231736). Transcription activator involved in the transcriptional regulation of terpene biosynthesis in glandular trichomes (PubMed:24884371, PubMed:30518626). Binds to the promoter of the linalool synthase TPS5 and promotes TPS5 gene transactivation (PubMed:24884371). Acts synergistically with EOT1 in the transactivation of TPS5 (PubMed:24884371). Involved in type VI glandular trichome development (PubMed:30518626). Involved in the activation of terpene synthases required for volatile mono- and sesquiterpenes synthesis by the glandular cells of type VI trichomes (PubMed:30518626). {ECO:0000269|PubMed:15231736, ECO:0000269|PubMed:24884371, ECO:0000269|PubMed:30518626}.
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Induced by methyl jasmonate and wounding. {ECO:0000269|PubMed:15231736}.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_022039009.11e-118transcription factor MYC4-like
SwissprotA0A060KY904e-88MYC1_SOLLC; Transcription factor MYC1
TrEMBLA0A251USL51e-117A0A251USL5_HELAN; Putative basic helix-loop-helix (BHLH) DNA-binding family protein
STRINGXP_009780487.12e-92(Nicotiana sylvestris)
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT4G17880.13e-78bHLH family protein
Publications ? help Back to Top
  1. Tomato Genome Consortium
    The tomato genome sequence provides insights into fleshy fruit evolution.
    Nature, 2012. 485(7400): p. 635-41
    [PMID:22660326]
  2. Spyropoulou EA,Haring MA,Schuurink RC
    RNA sequencing on Solanum lycopersicum trichomes identifies transcription factors that activate terpene synthase promoters.
    BMC Genomics, 2014. 15: p. 402
    [PMID:24884371]
  3. Xu J, et al.
    SlMYC1 Regulates Type VI Glandular Trichome Formation and Terpene Biosynthesis in Tomato Glandular Cells.
    Plant Cell, 2018. 30(12): p. 2988-3005
    [PMID:30518626]