PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

Itr_sc000002.1_g00019.1

Organism

Ipomoea trifida

Taxonomic ID

35884

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Solanales; Convolvulaceae; Ipomoeeae; Ipomoea

Family

E2F/DP

Protein Properties

Length: 370aa MW: 41463.4 Da PI: 9.2291

Description

E2F/DP family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Itr_sc000002.1_g00019.1	genome	Kazusa	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	E2F_TDP	72.6	4.3e-23	21	86	1	71
E2F_TDP 1 rkeksLrlltqkflkllekseegivtlnevakeLvsedvknkrRRiYDilNVLealnliekkekneirwkg 71 rkeksL++l+++fl+l+ + + + + l+++a++L v +rRRiYDi+N+Le+++l+++++kn+++wkg Itr_sc000002.1_g00019.1 21 RKEKSLGVLCSNFLRLYDRDDVDCIGLDHAADQL---GV--ERRRIYDIVNILESVGLLSRRAKNQYTWKG 86 79**************9999********.....****************************98 PP
2	E2F_TDP	74.4	1.2e-23	142	222	1	71
E2F_TDP 1 rkeksLrlltqkflkllekseegivtlnevakeLvse.....dvknkrRRiYDilNVLealnliek.....kekneirwkg 71 rkeksL lltq+f+kl+ +s+ + ++l+++a++L+ + +++k+RR+YDi+NV+ ++nliek + k+++rw+g Itr_sc000002.1_g00019.1 142 RKEKSLALLTQNFIKLFLCSDVEFISLDNAASALLGNmhdptAMRTKVRRLYDIANVFASMNLIEKirhpeSGKPAFRWIG 222 79******************************999*****************************99*****98 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Gene3D	G3DSA:1.10.10.10	3.3E-25	19	87	IPR011991	Winged helix-turn-helix DNA-binding domain
SuperFamily	SSF46785	9.6E-16	20	84	IPR011991	Winged helix-turn-helix DNA-binding domain
SMART	SM01372	4.8E-28	21	86	IPR003316	E2F/DP family, winged-helix DNA-binding domain
Pfam	PF02319	1.1E-20	22	86	IPR003316	E2F/DP family, winged-helix DNA-binding domain
Gene3D	G3DSA:1.10.10.10	5.1E-22	139	222	IPR011991	Winged helix-turn-helix DNA-binding domain
SMART	SM01372	7.6E-30	142	222	IPR003316	E2F/DP family, winged-helix DNA-binding domain
Pfam	PF02319	4.1E-18	143	222	IPR003316	E2F/DP family, winged-helix DNA-binding domain
SuperFamily	SSF46785	2.18E-12	144	222	IPR011991	Winged helix-turn-helix DNA-binding domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0005634	Cellular Component	nucleus
GO:0005667	Cellular Component	transcription factor complex
GO:0005737	Cellular Component	cytoplasm
GO:0003677	Molecular Function	DNA binding
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 370 aa Download sequence Send to blast
MSSSSIHSDS QSKNPTSLYS RKEKSLGVLC SNFLRLYDRD DVDCIGLDHA ADQLGVERRR 60 IYDIVNILES VGLLSRRAKN QYTWKGFAAI PRTLDALKGE GLREKLSGQN IANVSRENEY 120 RPPSNSSTKQ DNTHELIKGD NRKEKSLALL TQNFIKLFLC SDVEFISLDN AASALLGNMH 180 DPTAMRTKVR RLYDIANVFA SMNLIEKIRH PESGKPAFRW IGQVGNPGNG SRSAANVTDL 240 KRTFGADITN TVPKRCKAGS SSDWKPSEHA TQYAKHGNLK DENSKVSPDR HKHGSKDFEF 300 GPFSPSSVPR EVLGNINVGQ IPNWENLAST YRPRYCNKAL SDLFGHYVEA WNSWYVAADA 360 DEKQHDQHLP

Sequence ? help Back to Top

Protein Sequence Length: 370 aa Download sequence Send to blast

MSSSSIHSDS QSKNPTSLYS RKEKSLGVLC SNFLRLYDRD DVDCIGLDHA ADQLGVERRR  60
IYDIVNILES VGLLSRRAKN QYTWKGFAAI PRTLDALKGE GLREKLSGQN IANVSRENEY  120
RPPSNSSTKQ DNTHELIKGD NRKEKSLALL TQNFIKLFLC SDVEFISLDN AASALLGNMH  180
DPTAMRTKVR RLYDIANVFA SMNLIEKIRH PESGKPAFRW IGQVGNPGNG SRSAANVTDL  240
KRTFGADITN TVPKRCKAGS SSDWKPSEHA TQYAKHGNLK DENSKVSPDR HKHGSKDFEF  300
GPFSPSSVPR EVLGNINVGQ IPNWENLAST YRPRYCNKAL SDLFGHYVEA WNSWYVAADA  360
DEKQHDQHLP

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
4yo2_A	2e-36	20	212	3	226	Transcription factor E2F8
Search in ModeBase

Functional Description ? help Back to Top
Source	Description
UniProt	Inhibitor of E2F-dependent activation of gene expression. Binds specifically the E2 recognition site without interacting with DP proteins and prevents transcription activation by E2F/DP heterodimers. Does not bind retinoblastoma-related proteins. Acts as a growth regulator but is not associated with changes in the expression of cell cycle marker genes or in nuclear ploidy levels. Has no effect on cell proliferation, but may repress cell wall biosynthesis genes during cell elongation in differentiated cells. {ECO:0000269\|PubMed:11786543, ECO:0000269\|PubMed:11867638, ECO:0000269\|PubMed:15308755}.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_019185885.1	0.0	PREDICTED: E2F transcription factor-like E2FF isoform X1
Swissprot	Q8RWL0	1e-111	E2FF_ARATH; E2F transcription factor-like E2FF
TrEMBL	A0A328DSA6	0.0	A0A328DSA6_9ASTE; Uncharacterized protein
STRING	XP_009771455.1	1e-144	(Nicotiana sylvestris)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Asterids	OGEA2522	24	57

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT3G01330.1	1e-112	DP-E2F-like protein 3

Publications ? help Back to Top
Dohmann EM, et al. The Arabidopsis COP9 signalosome is essential for G2 phase progression and genomic stability. Development, 2008. 135(11): p. 2013-22 [PMID:18434413]