PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Home  TFext  BLAST  Prediction  Download  Help  About  Links  PlantRegMap
(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Jcr4S02162.30
Organism
Jatropha curcas
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Malpighiales; Euphorbiaceae; Crotonoideae; Jatropheae; Jatropha
Family E2F/DP
Protein Properties Length: 386aa    MW: 43991.6 Da    PI: 9.6208
Description E2F/DP family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Jcr4S02162.30genomeKazusaView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1E2F_TDP72.83.7e-231984171
        E2F_TDP  1 rkeksLrlltqkflkllekseegivtlnevakeLvsedvknkrRRiYDilNVLealnliekkekneirwkg 71
                   rkeksL++l+++fl+l++k   + + l+++a +L    v  +rRRiYD++N+Le+++++++k+kn+++wkg
  Jcr4S02162.30 19 RKEKSLGVLCTNFLTLYNKDGVDSIGLDDAAARL---GV--ERRRIYDVVNILESVGVVARKQKNQYSWKG 84
                   79*****************999************...**..****************************98 PP
2E2F_TDP74.79.8e-24145224271
        E2F_TDP   2 keksLrlltqkflkllekseegivtlnevakeLvse.....dvknkrRRiYDilNVLealnliek.....kekneirwkg 71 
                    +eksL+lltq+f+kl+ +++ +++tl+++a +L+ +      +++k+RR+YDi+NV++++nliek     ++k+++rw g
  Jcr4S02162.30 145 REKSLWLLTQNFVKLFLCTDVEMITLDNAAMSLLGNahnstAMRTKVRRLYDIANVFSSMNLIEKthhpdSRKPAFRWLG 224
                    79********************************999****************************9999999******87 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:1.10.10.102.3E-251786IPR011991Winged helix-turn-helix DNA-binding domain
SuperFamilySSF467854.9E-151982IPR011991Winged helix-turn-helix DNA-binding domain
SMARTSM013721.4E-251984IPR003316E2F/DP family, winged-helix DNA-binding domain
PfamPF023198.3E-202084IPR003316E2F/DP family, winged-helix DNA-binding domain
Gene3DG3DSA:1.10.10.102.5E-22140224IPR011991Winged helix-turn-helix DNA-binding domain
SMARTSM013724.6E-29144224IPR003316E2F/DP family, winged-helix DNA-binding domain
PfamPF023191.1E-18146224IPR003316E2F/DP family, winged-helix DNA-binding domain
SuperFamilySSF467851.68E-12146225IPR011991Winged helix-turn-helix DNA-binding domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0005634Cellular Componentnucleus
GO:0005667Cellular Componenttranscription factor complex
GO:0005737Cellular Componentcytoplasm
GO:0003677Molecular FunctionDNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 386 aa     Download sequence    Send to blast
MSSFVSRESD PSGRQFYCRK EKSLGVLCTN FLTLYNKDGV DSIGLDDAAA RLGVERRRIY  60
DVVNILESVG VVARKQKNQY SWKGFEAIPR ALEDLKEEGF RENFTVFGSC SSEKVANENE  120
NEESSSSRTD GQDNSSATSK SENKREKSLW LLTQNFVKLF LCTDVEMITL DNAAMSLLGN  180
AHNSTAMRTK VRRLYDIANV FSSMNLIEKT HHPDSRKPAF RWLGWTGNNG SVSLDKKEPR  240
KRTFGTEITN YITKRNKVDS LIDWDSNPKK ENVPVIIRCN SLENDCNENK LKLHTKHSSK  300
SFEFGPFTPV DTSITSDSGK KIASRIQDME SLTSTYYPQY HNRALSDLFV FLAIIWKLGN  360
RGMLKLLGKR RQRKDPDALI HGFYSR
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
4yo2_A2e-33192164228Transcription factor E2F8
Search in ModeBase
Nucleic Localization Signal ? help Back to Top
NLS
No. Start End Sequence
15576RRRIYDVVNILESVGVVARKQK
Functional Description ? help Back to Top
Source Description
UniProtInhibitor of E2F-dependent activation of gene expression. Binds specifically the E2 recognition site without interacting with DP proteins and prevents transcription activation by E2F/DP heterodimers. Does not bind retinoblastoma-related proteins. Acts as a growth regulator but is not associated with changes in the expression of cell cycle marker genes or in nuclear ploidy levels. Has no effect on cell proliferation, but may repress cell wall biosynthesis genes during cell elongation in differentiated cells. {ECO:0000269|PubMed:11786543, ECO:0000269|PubMed:11867638, ECO:0000269|PubMed:15308755}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_012082422.10.0E2F transcription factor-like E2FF
SwissprotQ8RWL01e-114E2FF_ARATH; E2F transcription factor-like E2FF
TrEMBLA0A067LLZ10.0A0A067LLZ1_JATCU; Uncharacterized protein
STRINGcassava4.1_008673m0.0(Manihot esculenta)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
FabidsOGEF36683366
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT3G01330.11e-111DP-E2F-like protein 3
Publications ? help Back to Top
  1. Dohmann EM, et al.
    The Arabidopsis COP9 signalosome is essential for G2 phase progression and genomic stability.
    Development, 2008. 135(11): p. 2013-22
    [PMID:18434413]