PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

Jcr4S04869.20

Organism

Jatropha curcas

Taxonomic ID

180498

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Malpighiales; Euphorbiaceae; Crotonoideae; Jatropheae; Jatropha

Family

NAC

Protein Properties

Length: 492aa MW: 54275.6 Da PI: 4.457

Description

NAC family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Jcr4S04869.20	genome	Kazusa	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	NAM	141.6	4.6e-44	10	128	1	128
NAM 1 lppGfrFhPtdeelvveyLkkkvegkkleleevikevdiykvePwdLpkkvkaeekewyfFskrdkkyatgkrknratksgyWkatgkdkevlskk 96 l+pGfrFhPtdeelv +yLk+kv++k++++ + i+ +diyk+ePwdLp k +++ w + +ky +g+++nrat++gyWk+tgkd+++ + Jcr4S04869.20 10 LAPGFRFHPTDEELVRYYLKRKVTNKPFRF-DPIAVIDIYKSEPWDLPGK---NKRIW----GNFRKYGNGSKTNRATEKGYWKTTGKDRPIQW-N 96 579************************9.99***********33...34555....445789*********************9.9 PP NAM 97 gelvglkktLvfykgrapkgektdWvmheyrl 128 +++vg+kktLv++ grap+ge+t+Wvmheyrl Jcr4S04869.20 97 SRTVGMKKTLVYHLGRAPRGERTNWVMHEYRL 128 99**************************98 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SuperFamily	SSF101941	1.01E-53	8	151	IPR003441	NAC domain
PROSITE profile	PS51005	50.276	10	151	IPR003441	NAC domain
Pfam	PF02365	1.4E-24	12	128	IPR003441	NAC domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0009819	Biological Process	drought recovery
GO:0010150	Biological Process	leaf senescence
GO:0045893	Biological Process	positive regulation of transcription, DNA-templated
GO:2000377	Biological Process	regulation of reactive oxygen species metabolic process
GO:0005634	Cellular Component	nucleus
GO:0005737	Cellular Component	cytoplasm
GO:0005886	Cellular Component	plasma membrane
GO:0016021	Cellular Component	integral component of membrane
GO:0003677	Molecular Function	DNA binding
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 492 aa Download sequence Send to blast
MVRGDSSTSL APGFRFHPTD EELVRYYLKR KVTNKPFRFD PIAVIDIYKS EPWDLPGKNK 60 RIWGNFRKYG NGSKTNRATE KGYWKTTGKD RPIQWNSRTV GMKKTLVYHL GRAPRGERTN 120 WVMHEYRLAD EDLQKAGIVQ DSFVLCRIFQ KSGTGPKNGE QYGAPFVEEE WDDDEVVALL 180 PGEEMVVTDE VAVGDDACVE ANDLDQNFDG IASGNASVPV NYYHGEASNY VEQSSGNCSG 240 DDQKPIIIGK EETQYGSNLP DDQNLFNLAG QYEVDAKAST GDSTPFDMVD EYLSFFDAND 300 DNLTFDPSEL MGTEYAIPDQ DHLFEKDVNG GAKAVPVVTS ELSEAHGNND ASSSKQLKPE 360 ATMFESDMKY PXXXMLGSIP APPAFASEFP VKDRALQLNA AQSSSSIRVT AGVIRIENIT 420 FGSSGMDWSS NKNQNVNIIL SFDMAQANVG PASLVPMGSF FSGKAMSTVS RGCQGSVIFG 480 VFMVWVGLVD WV

Sequence ? help Back to Top

Protein Sequence Length: 492 aa Download sequence Send to blast

MVRGDSSTSL APGFRFHPTD EELVRYYLKR KVTNKPFRFD PIAVIDIYKS EPWDLPGKNK  60
RIWGNFRKYG NGSKTNRATE KGYWKTTGKD RPIQWNSRTV GMKKTLVYHL GRAPRGERTN  120
WVMHEYRLAD EDLQKAGIVQ DSFVLCRIFQ KSGTGPKNGE QYGAPFVEEE WDDDEVVALL  180
PGEEMVVTDE VAVGDDACVE ANDLDQNFDG IASGNASVPV NYYHGEASNY VEQSSGNCSG  240
DDQKPIIIGK EETQYGSNLP DDQNLFNLAG QYEVDAKAST GDSTPFDMVD EYLSFFDAND  300
DNLTFDPSEL MGTEYAIPDQ DHLFEKDVNG GAKAVPVVTS ELSEAHGNND ASSSKQLKPE  360
ATMFESDMKY PXXXMLGSIP APPAFASEFP VKDRALQLNA AQSSSSIRVT AGVIRIENIT  420
FGSSGMDWSS NKNQNVNIIL SFDMAQANVG PASLVPMGSF FSGKAMSTVS RGCQGSVIFG  480
VFMVWVGLVD WV

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
1ut4_A	1e-40	6	157	13	171	NO APICAL MERISTEM PROTEIN
1ut4_B	1e-40	6	157	13	171	NO APICAL MERISTEM PROTEIN
1ut7_A	1e-40	6	157	13	171	NO APICAL MERISTEM PROTEIN
1ut7_B	1e-40	6	157	13	171	NO APICAL MERISTEM PROTEIN
3swm_A	1e-40	6	157	16	174	NAC domain-containing protein 19
3swm_B	1e-40	6	157	16	174	NAC domain-containing protein 19
3swm_C	1e-40	6	157	16	174	NAC domain-containing protein 19
3swm_D	1e-40	6	157	16	174	NAC domain-containing protein 19
3swp_A	1e-40	6	157	16	174	NAC domain-containing protein 19
3swp_B	1e-40	6	157	16	174	NAC domain-containing protein 19
3swp_C	1e-40	6	157	16	174	NAC domain-containing protein 19
3swp_D	1e-40	6	157	16	174	NAC domain-containing protein 19
4dul_A	1e-40	6	157	13	171	NAC domain-containing protein 19
4dul_B	1e-40	6	157	13	171	NAC domain-containing protein 19
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Functional Description ? help Back to Top
Source	Description
UniProt	Transcriptional activator activated by proteolytic cleavage through regulated intramembrane proteolysis (RIP) (Ref.6, PubMed:24323506, PubMed:25219309). Promotes reactive oxygen species (ROS) production during drought-induced leaf senescence. In response to abscisic acid (ABA)-mediated drought stress signals, binds directly to the promoters of RBOHC and RBOHE genes, encoding ROS biosynthetic enzymes, resulting in ROS accumulation and triggering leaf senescence via programmed cell death (PCD). ROS-induced leaf senescence sustains plant survival under drought conditions (PubMed:22313226). Involved in heat stress response. Modulates PCD through a ROS-mediated positive feedback control under heat stress conditions. This may provide an adaptation strategy for plant survival under extreme heat stress conditions (PubMed:25219309). Acts as repressor in preventing anther dehiscence during stamen development by suppressing genes that participate in jasmonic acid (JA) biosynthesis, such as DAD1, AOS, AOC3, OPR3 and 4CLL5/OPCL1 (PubMed:24323506). {ECO:0000269\|PubMed:22313226, ECO:0000269\|PubMed:24323506, ECO:0000269\|PubMed:25219309, ECO:0000269\|Ref.6}.

Binding Motif ? help Back to Top
Motif ID	Method	Source	Motif file
MP00343	DAP	Transfer from AT3G10500	Download

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: By abscisic acid (ABA) (PubMed:22313226, PubMed:25219309). Induced by heat shock (PubMed:25219309). Induced by cold, drought stress and methyl methanesulfonate (MMS) treatment (PubMed:17158162). {ECO:0000269\|PubMed:17158162, ECO:0000269\|PubMed:22313226, ECO:0000269\|PubMed:25219309}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	Retrieve

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	KC775322	1e-165	KC775322.1 Jatropha curcas NAC transcription factor 044 gene, complete cds.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_012090539.2	0.0	NAC domain-containing protein 78
Swissprot	Q949N0	1e-132	NAC53_ARATH; NAC domain-containing protein 53
TrEMBL	R4NHQ2	0.0	R4NHQ2_JATCU; NAC transcription factor 044
STRING	cassava4.1_004618m	0.0	(Manihot esculenta)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Fabids	OGEF5347	32	47

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT3G10500.1	1e-132	NAC domain containing protein 53

Publications ? help Back to Top
Duarte JM, et al. Expression pattern shifts following duplication indicative of subfunctionalization and neofunctionalization in regulatory genes of Arabidopsis. Mol. Biol. Evol., 2006. 23(2): p. 469-78 [PMID:16280546] Ding Y, et al. Four distinct types of dehydration stress memory genes in Arabidopsis thaliana. BMC Plant Biol., 2013. 13: p. 229 [PMID:24377444] Vermeirssen V,De Clercq I,Van Parys T,Van Breusegem F,Van de Peer Y Arabidopsis ensemble reverse-engineered gene regulatory network discloses interconnected transcription factors in oxidative stress. Plant Cell, 2014. 26(12): p. 4656-79 [PMID:25549671] Gladman NP,Marshall RS,Lee KH,Vierstra RD The Proteasome Stress Regulon Is Controlled by a Pair of NAC Transcription Factors in Arabidopsis. Plant Cell, 2016. 28(6): p. 1279-96 [PMID:27194708] Sanz-Fernández M, et al. Screening Arabidopsis mutants in genes useful for phytoremediation. J. Hazard. Mater., 2017. 335: p. 143-151 [PMID:28441590]