PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Jcr4S07554.10
Organism
Jatropha curcas
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Malpighiales; Euphorbiaceae; Crotonoideae; Jatropheae; Jatropha
Family C2H2
Protein Properties Length: 371aa    MW: 43089 Da    PI: 6.5522
Description C2H2 family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Jcr4S07554.10genomeKazusaView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1zf-C2H212.30.00052125147323
                    ET..TTTEEESSHHHHHHHHHHT CS
        zf-C2H2   3 Cp..dCgksFsrksnLkrHirtH 23 
                    C+   Cgk+F +   L++H   H
  Jcr4S07554.10 125 CSfeGCGKTFIDAGALRKHSHIH 147
                    77779**************7766 PP
2zf-C2H215.64.5e-05194218123
                    EEET..TTTEEESSHHHHHHHHHHT CS
        zf-C2H2   1 ykCp..dCgksFsrksnLkrHirtH 23 
                    + Cp   Cgk++ + + Lk+Hi  H
  Jcr4S07554.10 194 HICPypECGKRYAHEYKLKNHIAAH 218
                    679999****************995 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SuperFamilySSF576672.39E-6118159No hitNo description
Gene3DG3DSA:3.30.160.607.1E-14118148IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
PROSITE profilePS5015710.783123152IPR007087Zinc finger, C2H2
SMARTSM003550.0037123147IPR015880Zinc finger, C2H2-like
PROSITE patternPS000280125147IPR007087Zinc finger, C2H2
Gene3DG3DSA:3.30.160.606.5E-7149185IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
SMARTSM0035522152188IPR015880Zinc finger, C2H2-like
SuperFamilySSF576671.15E-9174220No hitNo description
Gene3DG3DSA:3.30.160.604.8E-11186220IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
SMARTSM003550.051194218IPR015880Zinc finger, C2H2-like
PROSITE profilePS501579.598194223IPR007087Zinc finger, C2H2
PROSITE patternPS000280196219IPR007087Zinc finger, C2H2
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0003676Molecular Functionnucleic acid binding
GO:0046872Molecular Functionmetal ion binding
Sequence ? help Back to Top
Protein Sequence    Length: 371 aa     Download sequence    Send to blast
METQFTHNLF ERRPIIKSKT PAVKWFREWV PQDVVATGGK CSLMRWVNQF ELCGVLVLQQ  60
FKANMCSLSS SQFVIKFRQR YFGEASYSCI WGWTXNQLKA LKEKAKEPPP PEPEPEPTTE  120
VLFLCSFEGC GKTFIDAGAL RKHSHIHGER QYVCHYEGCG KEKEILYVHM KAVAFSLDFN  180
LRSHMKTHSQ ENYHICPYPE CGKRYAHEYK LKNHIAAHHE KHSAAETVKY AAPMEKAYIH  240
EYKLKLHLRK EHPGHFPDEN AENASPNGDN EMDEGSDQDA YPEKRVNGKN QKHSRSKPNL  300
KMPPAKITQR KGSSPARATL NVVKKSWPVK EEIYEEEDSE ETEEEDRDKA EDGWRYGENN  360
EDDDEETEYE D
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1ubd_C2e-1613021840117PROTEIN (YY1 ZINC FINGER DOMAIN)
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtDual-function transcription factor with both repression and activation activities. Binds to 5'-CCATATT-3' motif in target gene promoters (e.g. ABR1) (PubMed:26961720). Binds also to G-rich DNA motif 5'-GGGGGCAGTGG-3' (PubMed:22508367). Regulates the expression of genes involved in diverse cellular pathways, including glucose metabolism, photosynthesis, phototropism and stress response (e.g. salt, drought and osmotic stress) (PubMed:22508367, PubMed:26961720). Regulates plant immunity, especially during necrotrophic fungal infection (e.g. B.cinerea) (PubMed:24451981). Binds to ABR1 promoter and promotes its expression, thus negatively regulating the abscisic acid (ABA) signaling pathway. Represses ABA- and salt-responsive genes expression (PubMed:26961720). {ECO:0000269|PubMed:22508367, ECO:0000269|PubMed:24451981, ECO:0000269|PubMed:26961720}.
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Induced by abscisic acid (ABA) in an ABI1- and ABI4-dependent manner. Stimulated by stress conditions including high salt, osmotic stress (e.g. mannitol) and dehydration. May be induced by ABI4 but repressed by ABR1. Repressed by darkness but induced by light. {ECO:0000269|PubMed:26961720}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_012066637.11e-176uncharacterized zinc finger protein At4g06634
SwissprotQ2V3L31e-103YY1_ARATH; Zinc finger transcription factor YY1
TrEMBLA0A067L1W21e-175A0A067L1W2_JATCU; Uncharacterized protein
STRINGcassava4.1_009859m1e-153(Manihot esculenta)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
FabidsOGEF56493354
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT4G06634.13e-81C2H2 family protein
Publications ? help Back to Top
  1. Kumekawa N,Hosouchi T,Tsuruoka H,Kotani H
    The size and sequence organization of the centromeric region of Arabidopsis thaliana chromosome 4.
    DNA Res., 2001. 8(6): p. 285-90
    [PMID:11853315]
  2. Li T,Wu XY,Li H,Song JH,Liu JY
    A Dual-Function Transcription Factor, AtYY1, Is a Novel Negative Regulator of the Arabidopsis ABA Response Network.
    Mol Plant, 2016. 9(5): p. 650-661
    [PMID:26961720]
  3. Wu XY,Li T
    A Casein Kinase II Phosphorylation Site in AtYY1 Affects Its Activity, Stability, and Function in the ABA Response.
    Front Plant Sci, 2017. 8: p. 323
    [PMID:28348572]