PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Jcr4S11472.20
Organism
Jatropha curcas
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Malpighiales; Euphorbiaceae; Crotonoideae; Jatropheae; Jatropha
Family C2H2
Protein Properties Length: 358aa    MW: 41233.9 Da    PI: 6.2035
Description C2H2 family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Jcr4S11472.20genomeKazusaView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1zf-C2H212.40.000582104323
                    ET..TTTEEESSHHHHHHHHHHT CS
        zf-C2H2   3 Cp..dCgksFsrksnLkrHirtH 23 
                    C+   Cgk+F +   L++H   H
  Jcr4S11472.20  82 CSfeGCGKTFIDAGALRKHSHIH 104
                    77779**************7766 PP
2zf-C2H215.74.3e-05151175123
                    EEET..TTTEEESSHHHHHHHHHHT CS
        zf-C2H2   1 ykCp..dCgksFsrksnLkrHirtH 23 
                    + Cp   Cgk++ + + Lk+Hi  H
  Jcr4S11472.20 151 HICPypECGKRYAHEYKLKNHIAAH 175
                    679999****************995 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:3.30.160.606.8E-1475105IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
SuperFamilySSF576672.28E-675116No hitNo description
SMARTSM003550.003780104IPR015880Zinc finger, C2H2-like
PROSITE profilePS5015710.78380109IPR007087Zinc finger, C2H2
PROSITE patternPS00028082104IPR007087Zinc finger, C2H2
Gene3DG3DSA:3.30.160.606.4E-7106142IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
SMARTSM0035522109145IPR015880Zinc finger, C2H2-like
SuperFamilySSF576672.56E-9131177No hitNo description
Gene3DG3DSA:3.30.160.604.6E-11143177IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
SMARTSM003550.051151175IPR015880Zinc finger, C2H2-like
PROSITE profilePS501579.598151180IPR007087Zinc finger, C2H2
PROSITE patternPS000280153176IPR007087Zinc finger, C2H2
Gene3DG3DSA:3.30.160.606.3E-9209237IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
SuperFamilySSF576678.81E-5209237No hitNo description
SMARTSM003550.04214239IPR015880Zinc finger, C2H2-like
PROSITE profilePS5015710.616214244IPR007087Zinc finger, C2H2
PROSITE patternPS000280216239IPR007087Zinc finger, C2H2
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0045892Biological Processnegative regulation of transcription, DNA-templated
GO:0045893Biological Processpositive regulation of transcription, DNA-templated
GO:0005634Cellular Componentnucleus
GO:0043565Molecular Functionsequence-specific DNA binding
GO:0046872Molecular Functionmetal ion binding
Sequence ? help Back to Top
Protein Sequence    Length: 358 aa     Download sequence    Send to blast
GAPRCRGNWW EVFPYEMGKW SINLSYVEYW YCNSLRQICA VFLVHNLLLS SENQLKALKE  60
KAKEPPPPEP EPEPTTEVLF LCSFEGCGKT FIDAGALRKH SHIHGERQYV CHYEGCGKEK  120
EILYVHMKAV AFSLDFNLRS HMKTHSQENY HICPYPECGK RYAHEYKLKN HIAAHHEKHS  180
AAETVKYAAP MEKVTKVSKP SAATYGSGSS DRPYACPYEG CMKAYIHEYK LKLHLRKEHP  240
GHFPDENAEN ASPNGDNEMD EGSDQDAYPE KRVNGKNQKH SRSKPNLKMP PAKITQRKGS  300
SPARATLNVV KKSWPVKEEI YEEEDSEETE EEDRDKAEDG WRYGENNEDD DEETEYED
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1ubd_C1e-168717540117PROTEIN (YY1 ZINC FINGER DOMAIN)
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtDual-function transcription factor with both repression and activation activities. Binds to 5'-CCATATT-3' motif in target gene promoters (e.g. ABR1) (PubMed:26961720). Binds also to G-rich DNA motif 5'-GGGGGCAGTGG-3' (PubMed:22508367). Regulates the expression of genes involved in diverse cellular pathways, including glucose metabolism, photosynthesis, phototropism and stress response (e.g. salt, drought and osmotic stress) (PubMed:22508367, PubMed:26961720). Regulates plant immunity, especially during necrotrophic fungal infection (e.g. B.cinerea) (PubMed:24451981). Binds to ABR1 promoter and promotes its expression, thus negatively regulating the abscisic acid (ABA) signaling pathway. Represses ABA- and salt-responsive genes expression (PubMed:26961720). {ECO:0000269|PubMed:22508367, ECO:0000269|PubMed:24451981, ECO:0000269|PubMed:26961720}.
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Induced by abscisic acid (ABA) in an ABI1- and ABI4-dependent manner. Stimulated by stress conditions including high salt, osmotic stress (e.g. mannitol) and dehydration. May be induced by ABI4 but repressed by ABR1. Repressed by darkness but induced by light. {ECO:0000269|PubMed:26961720}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankEF1485071e-51EF148507.1 Populus trichocarpa x Populus deltoides clone WS0131_N16 unknown mRNA.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_012066637.11e-174uncharacterized zinc finger protein At4g06634
SwissprotQ2V3L31e-102YY1_ARATH; Zinc finger transcription factor YY1
TrEMBLA0A067L1W21e-173A0A067L1W2_JATCU; Uncharacterized protein
STRINGcassava4.1_009859m1e-151(Manihot esculenta)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
FabidsOGEF56493354
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT4G06634.21e-98C2H2 family protein
Publications ? help Back to Top
  1. Kumekawa N,Hosouchi T,Tsuruoka H,Kotani H
    The size and sequence organization of the centromeric region of Arabidopsis thaliana chromosome 4.
    DNA Res., 2001. 8(6): p. 285-90
    [PMID:11853315]
  2. Li T,Wu XY,Li H,Song JH,Liu JY
    A Dual-Function Transcription Factor, AtYY1, Is a Novel Negative Regulator of the Arabidopsis ABA Response Network.
    Mol Plant, 2016. 9(5): p. 650-661
    [PMID:26961720]
  3. Wu XY,Li T
    A Casein Kinase II Phosphorylation Site in AtYY1 Affects Its Activity, Stability, and Function in the ABA Response.
    Front Plant Sci, 2017. 8: p. 323
    [PMID:28348572]