PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID KFK24845.1
Organism
Arabis alpina
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Arabideae; Arabis
Family HSF
Protein Properties Length: 376aa    MW: 42499.5 Da    PI: 4.8432
Description HSF family protein
Gene Model
Gene Model ID Type Source Coding Sequence
KFK24845.1genomeMPIPBRView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1HSF_DNA-bind1071.5e-33231142102
                   HHHHHHHHHCTGGGTTTSEESSSSSEEEES-HHHHHHHTHHHHSTT--HHHHHHHHHHTTEEE---SSBTTTTXTTSEEEEESXXXXXXXXXXXXXX CS
  HSF_DNA-bind   2 FlkklyeiledeelkeliswsengnsfvvldeeefakkvLpkyFkhsnfaSFvRQLnmYgFkkvkdeekkskskekiweFkhksFkkgkkellekik 98 
                   Fl+k++++++d++l+ +isw  +g sfvv+d+ ef++ +Lpk Fkh+nf+SFvRQLn+YgF+k+++++         weF+++ F +gkk+ll++i+
    KFK24845.1  23 FLSKTFDLVDDPSLDPVISWGLTGASFVVWDPLEFSRIILPKNFKHNNFSSFVRQLNTYGFRKIDTDK---------WEFANEGFLRGKKHLLKNIH 110
                   9****************************************************************999.........******************** PP

                   XXXX CS
  HSF_DNA-bind  99 rkks 102
                   r++s
    KFK24845.1 111 RRRS 114
                   *987 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SuperFamilySSF467854.35E-3318112IPR011991Winged helix-turn-helix DNA-binding domain
SMARTSM004152.1E-5519112IPR000232Heat shock factor (HSF)-type, DNA-binding
Gene3DG3DSA:1.10.10.102.7E-3520112IPR011991Winged helix-turn-helix DNA-binding domain
PfamPF004471.6E-2923112IPR000232Heat shock factor (HSF)-type, DNA-binding
PRINTSPR000567.0E-182346IPR000232Heat shock factor (HSF)-type, DNA-binding
PRINTSPR000567.0E-186173IPR000232Heat shock factor (HSF)-type, DNA-binding
PROSITE patternPS0043406286IPR000232Heat shock factor (HSF)-type, DNA-binding
PRINTSPR000567.0E-187486IPR000232Heat shock factor (HSF)-type, DNA-binding
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0009408Biological Processresponse to heat
GO:0010200Biological Processresponse to chitin
GO:0005634Cellular Componentnucleus
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
GO:0043565Molecular Functionsequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 376 aa     Download sequence    Send to blast
MGFSSSPLPL PLDILQGNPI PPFLSKTFDL VDDPSLDPVI SWGLTGASFV VWDPLEFSRI  60
ILPKNFKHNN FSSFVRQLNT YGFRKIDTDK WEFANEGFLR GKKHLLKNIH RRRSPQSNQT  120
CSSSSSQSQS QGSPTEVGEE IEKLRKERRA LMEEMVELQQ QHRGTARHVD TVNQRLIAAE  180
KRQKQMLSFL AKLFQNPSFL GRLKNLKGGG EREALGSEKA RRKFIKHKQP QDSPTGGNIV  240
KYEADDWERL LMTDEDIPDA GQEMTSITDS KGKNLMNPSE EEMMNPDDLM SFPFPGEVDG  300
MIKQEETWSM GFDTTSFNND NVWGNTLDNN ISEFGSVAAT TSDGLPDVYW EQFAAGITDT  360
GFNWPANDDH SPMDDP
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
2ldu_A8e-242011717125Heat shock factor protein 1
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtTranscriptional activator that specifically binds DNA sequence 5'-AGAAnnTTCT-3' known as heat shock promoter elements (HSE). Involved in heat stress response. Activated by DREB2A under heat stress. {ECO:0000269|PubMed:17999647, ECO:0000269|PubMed:18261981}.
Cis-element ? help Back to Top
SourceLink
PlantRegMapKFK24845.1
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: By heat stress. {ECO:0000269|PubMed:17999647, ECO:0000269|PubMed:18261981}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_002873110.10.0heat stress transcription factor A-3
SwissprotQ8GYY10.0HSFA3_ARATH; Heat stress transcription factor A-3
TrEMBLA0A087G4P30.0A0A087G4P3_ARAAL; Uncharacterized protein
STRINGA0A087G4P30.0(Arabis alpina)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MalvidsOGEM109502529
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT5G03720.10.0heat shock transcription factor A3
Publications ? help Back to Top
  1. Jung HS, et al.
    Subset of heat-shock transcription factors required for the early response of Arabidopsis to excess light.
    Proc. Natl. Acad. Sci. U.S.A., 2013. 110(35): p. 14474-9
    [PMID:23918368]
  2. Ding Y, et al.
    Four distinct types of dehydration stress memory genes in Arabidopsis thaliana.
    BMC Plant Biol., 2013. 13: p. 229
    [PMID:24377444]
  3. Nie S,Yue H,Xing D
    A Potential Role for Mitochondrial Produced Reactive Oxygen Species in Salicylic Acid-Mediated Plant Acquired Thermotolerance.
    Plant Physiol., 2016.
    [PMID:26099269]
  4. Hu Z, et al.
    Histone acetyltransferase GCN5 is essential for heat stress-responsive gene activation and thermotolerance in Arabidopsis.
    Plant J., 2015. 84(6): p. 1178-91
    [PMID:26576681]
  5. Song C,Chung WS,Lim CO
    Overexpression of Heat Shock Factor Gene HsfA3 Increases Galactinol Levels and Oxidative Stress Tolerance in Arabidopsis.
    Mol. Cells, 2016. 39(6): p. 477-83
    [PMID:27109422]
  6. Kim GD,Cho YH,Lee BH,Yoo SD
    STABILIZED1 Modulates Pre-mRNA Splicing for Thermotolerance.
    Plant Physiol., 2017. 173(4): p. 2370-2382
    [PMID:28223317]
  7. Song C,Lee J,Kim T,Hong JC,Lim CO
    VOZ1, a transcriptional repressor of DREB2C, mediates heat stress responses in Arabidopsis.
    Planta, 2018. 247(6): p. 1439-1448
    [PMID:29536220]