PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

KFK27081.1

Organism

Arabis alpina

Taxonomic ID

50452

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Arabideae; Arabis

Family

bHLH

Protein Properties

Length: 234aa MW: 25529.9 Da PI: 9.1273

Description

bHLH family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
KFK27081.1	genome	MPIPBR	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	HLH	38.2	2.6e-12	75	122	4	54
HHHHHHHHHHHHHHHHHHHHHCTSCCC...TTS-STCHHHHHHHHHHHHHH CS HLH 4 ahnerErrRRdriNsafeeLrellPkaskapskKlsKaeiLekAveYIksL 54 ++ rE++RRdr+N++f eL ++l + + +K +Ka+iL Av+ + +L KFK27081.1 75 SKACREKQRRDRLNDKFMELGTILEPG---NPPKTDKAAILVDAVRMVTQL 122 5678********************8...78************99988 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SuperFamily	SSF47459	3.79E-14	62	137	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
PROSITE profile	PS50888	13.605	71	122	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
Gene3D	G3DSA:4.10.280.10	7.3E-14	74	145	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
Pfam	PF00010	5.7E-10	75	122	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
SMART	SM00353	7.6E-10	77	128	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
CDD	cd00083	5.32E-10	79	127	No hit	No description
CDD	cd14686	0.00538	137	169	No hit	No description

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0046983	Molecular Function	protein dimerization activity

Sequence ? help Back to Top
Protein Sequence Length: 234 aa Download sequence Send to blast
MVSPENANWI CDLIDADYGS FTIQGPGFSW PVQQPIGVSS NSSAGVDGSV GNSEASKEPG 60 SKKRGRSESS SATSSKACRE KQRRDRLNDK FMELGTILEP GNPPKTDKAA ILVDAVRMVT 120 QLRGEAQKLK DSNSSLQDKI KELKTEKNEL RDEKQRLKTE KEKLEQQLKA MNAPQPSFFP 180 APPMMPTAFA SAQGQAPGNK MVPIISYPGV AMWQFMPPAS VDTSQDHVLR PPVA

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription factor. Plays a role in resistance to amide-linked indole-3-acetic acid (IAA) conjugates such as IAA-Leu and IAA-Phe. May regulate gene expression in response to metal homeostasis changes. {ECO:0000269\|PubMed:17028341}.

Cis-element ? help Back to Top
Source	Link
PlantRegMap	KFK27081.1

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	AF488629	0.0	AF488629.1 Arabidopsis thaliana clone bHLH105 putative bHLH transcription factor mRNA, complete cds.
GenBank	AY054585	0.0	AY054585.1 Arabidopsis thaliana Unknown protein (At5g54680; K5F14.2) mRNA, complete cds.
GenBank	BT002189	0.0	BT002189.1 Arabidopsis thaliana Unknown protein (At5g54680) mRNA, complete cds.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	NP_200279.1	1e-170	basic helix-loop-helix (bHLH) DNA-binding superfamily protein
Refseq	XP_020888968.1	1e-170	transcription factor ILR3
Swissprot	Q9FH37	1e-171	ILR3_ARATH; Transcription factor ILR3
TrEMBL	A0A087GB29	1e-171	A0A087GB29_ARAAL; Uncharacterized protein
STRING	A0A087GB29	1e-172	(Arabis alpina)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Malvids	OGEM1437	28	90

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT5G54680.1	1e-126	bHLH family protein

Publications ? help Back to Top
Li X,Zhang H,Ai Q,Liang G,Yu D Two bHLH Transcription Factors, bHLH34 and bHLH104, Regulate Iron Homeostasis in Arabidopsis thaliana. Plant Physiol., 2016. 170(4): p. 2478-93 [PMID:26921305] Aparicio F,Pallás V The coat protein of Alfalfa mosaic virus interacts and interferes with the transcriptional activity of the bHLH transcription factor ILR3 promoting salicylic acid-dependent defence signalling response. Mol. Plant Pathol., 2017. 18(2): p. 173-186 [PMID:26929142] Liang G,Zhang H,Li X,Ai Q,Yu D bHLH transcription factor bHLH115 regulates iron homeostasis in Arabidopsis thaliana. J. Exp. Bot., 2017. 68(7): p. 1743-1755 [PMID:28369511] Ezer D, et al. The G-Box Transcriptional Regulatory Code in Arabidopsis. Plant Physiol., 2017. 175(2): p. 628-640 [PMID:28864470] Li B, et al. Network-Guided Discovery of Extensive Epistasis between Transcription Factors Involved in Aliphatic Glucosinolate Biosynthesis. Plant Cell, 2018. 30(1): p. 178-195 [PMID:29317470] Min JH, et al. Arabidopsis Basic Helix-Loop-Helix 34 (bHLH34) Is Involved in Glucose Signaling through Binding to a GAGA Cis-Element. Front Plant Sci, 2017. 8: p. 2100 [PMID:29321786] Samira R, et al. The bHLH transcription factor ILR3 modulates multiple stress responses in Arabidopsis. Plant Mol. Biol., 2018. 97(4-5): p. 297-309 [PMID:29882068]