PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

KFK30383.1

Organism

Arabis alpina

Taxonomic ID

50452

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Arabideae; Arabis

Family

GRF

Protein Properties

Length: 500aa MW: 55408.5 Da PI: 8.9598

Description

GRF family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
KFK30383.1	genome	MPIPBR	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	WRC	78.4	7.1e-25	209	252	1	44
WRC 1 daepgrCrRtDGKkWRCsrrvlegkklCErHlhrgrsrsrkske 44 d+epgrCrRtDGKkWRCsr++++++k+CErH++rgr+rsrk +e KFK30383.1 209 DPEPGRCRRTDGKKWRCSRDAVPDQKYCERHINRGRHRSRKLVE 252 79***************************************998 PP
2	QLQ	50.5	6.3e-18	145	181	1	37
QLQ 1 saFTaaQlqlLksQilAyKyLaanqPvPpeLlqaiqk 37 ++FT +Q+++L+ Q+l+yKy+ an+PvP+ Ll i+k KFK30383.1 145 GPFTLTQWAELELQALIYKYITANVPVPSSLLISIKK 181 59******************************99986 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SMART	SM00951	7.5E-11	145	181	IPR014978	Glutamine-Leucine-Glutamine, QLQ
Pfam	PF08880	1.9E-12	146	179	IPR014978	Glutamine-Leucine-Glutamine, QLQ
PROSITE profile	PS51666	20.749	146	181	IPR014978	Glutamine-Leucine-Glutamine, QLQ
PROSITE profile	PS51667	25.463	209	253	IPR014977	WRC domain
Pfam	PF08879	3.7E-21	210	252	IPR014977	WRC domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0005634	Cellular Component	nucleus
GO:0005524	Molecular Function	ATP binding

Sequence ? help Back to Top
Protein Sequence Length: 500 aa Download sequence Send to blast
MDIETHIHGS VTKELRGTKQ DRSIFNSDEF LQRSSKLSRT TQEEQEEVNL SSYSKTMSFH 60 QGIPLMRSTS TSLLSSDSRR QEHMLSFSDK PEPLDFSKHV GLENHKNTLS PILAPPSYYK 120 SSGGGYGSGG MMMSMQGNSF NGVKGPFTLT QWAELELQAL IYKYITANVP VPSSLLISIK 180 KSFYPYGSLP PSAFGWGAFH LGFAGGNMDP EPGRCRRTDG KKWRCSRDAV PDQKYCERHI 240 NRGRHRSRKL VEVQSSLTAT AAASKAVTTP LQSAVAKGNA RASSKNRLDQ YINPSTDSLP 300 NNRVQNPLYP STVNIPPKES PIVHEKHRNN NNNNPFEFGH ISSDSLLNPN SAKSYGSSYL 360 DFSSNHEKQH PNNSWPDELK PDWTQLSMAI PITSSSPSST HNTQEKLTLS PLRLSREVDL 420 SIQTEETTLQ PEQKVNTWIP ISWGNSLGGP LGEVLNSTTN SPTGVMQQST FCSLSNSSSV 480 SSPIAENNNR NNGDYFHYTT

Sequence ? help Back to Top

Protein Sequence Length: 500 aa Download sequence Send to blast

MDIETHIHGS VTKELRGTKQ DRSIFNSDEF LQRSSKLSRT TQEEQEEVNL SSYSKTMSFH  60
QGIPLMRSTS TSLLSSDSRR QEHMLSFSDK PEPLDFSKHV GLENHKNTLS PILAPPSYYK  120
SSGGGYGSGG MMMSMQGNSF NGVKGPFTLT QWAELELQAL IYKYITANVP VPSSLLISIK  180
KSFYPYGSLP PSAFGWGAFH LGFAGGNMDP EPGRCRRTDG KKWRCSRDAV PDQKYCERHI  240
NRGRHRSRKL VEVQSSLTAT AAASKAVTTP LQSAVAKGNA RASSKNRLDQ YINPSTDSLP  300
NNRVQNPLYP STVNIPPKES PIVHEKHRNN NNNNPFEFGH ISSDSLLNPN SAKSYGSSYL  360
DFSSNHEKQH PNNSWPDELK PDWTQLSMAI PITSSSPSST HNTQEKLTLS PLRLSREVDL  420
SIQTEETTLQ PEQKVNTWIP ISWGNSLGGP LGEVLNSTTN SPTGVMQQST FCSLSNSSSV  480
SSPIAENNNR NNGDYFHYTT

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription activator that plays a role in the regulation of cell expansion in leaf and cotyledons tissues. Component of a network formed by miR396, the GRFs and their interacting factors (GIFs) acting in the regulation of meristem function, at least partially through the control of cell proliferation. {ECO:0000269\|PubMed:12974814, ECO:0000269\|PubMed:15326298, ECO:0000269\|PubMed:20023165, ECO:0000269\|PubMed:21036927}.

Cis-element ? help Back to Top
Source	Link
PlantRegMap	KFK30383.1

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: microRNA 396 (miR396a or miR396b) negatively regulates growth-regulating factors (GRF1-4 and GRF7-9). {ECO:0000269\|PubMed:15200956, ECO:0000269\|PubMed:19453503, ECO:0000269\|PubMed:20023165}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	NP_195488.2	0.0	growth-regulating factor 2
Swissprot	Q8L8A8	0.0	GRF2_ARATH; Growth-regulating factor 2
TrEMBL	A0A087GKI1	0.0	A0A087GKI1_ARAAL; Uncharacterized protein
STRING	A0A087GKI1	0.0	(Arabis alpina)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Malvids	OGEM1454	28	86

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT4G37740.1	0.0	growth-regulating factor 2

Publications ? help Back to Top
Casadevall R,Rodriguez RE,Debernardi JM,Palatnik JF,Casati P Repression of growth regulating factors by the microRNA396 inhibits cell proliferation by UV-B radiation in Arabidopsis leaves. Plant Cell, 2013. 25(9): p. 3570-83 [PMID:24076976] Liu J,Rice JH,Chen N,Baum TJ,Hewezi T Synchronization of developmental processes and defense signaling by growth regulating transcription factors. PLoS ONE, 2014. 9(5): p. e98477 [PMID:24875638] Cao Y,Han Y,Jin Q,Lin Y,Cai Y Comparative Genomic Analysis of the GRF Genes in Chinese Pear (Pyrus bretschneideri Rehd), Poplar (Populous), Grape (Vitis vinifera), Arabidopsis and Rice (Oryza sativa). Front Plant Sci, 2016. 7: p. 1750 [PMID:27933074]