PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID KFK33910.1
Organism
Arabis alpina
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Arabideae; Arabis
Family C2H2
Protein Properties Length: 255aa    MW: 27243.2 Da    PI: 5.4566
Description C2H2 family protein
Gene Model
Gene Model ID Type Source Coding Sequence
KFK33910.1genomeMPIPBRView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1zf-C2H213.50.00021229251223
                 EETTTTEEESSHHHHHHHHHH.T CS
     zf-C2H2   2 kCpdCgksFsrksnLkrHirt.H 23 
                 +C+ C+k+F++   L++H +  H
  KFK33910.1 229 SCGSCKKTFNSDNALESHNKAkH 251
                 6*****************88766 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PfamPF030661.3E-93162No hitNo description
PROSITE profilePS5015710.575228255IPR007087Zinc finger, C2H2
PROSITE patternPS000280230251IPR007087Zinc finger, C2H2
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0009294Biological ProcessDNA mediated transformation
GO:0009944Biological Processpolarity specification of adaxial/abaxial axis
GO:0010162Biological Processseed dormancy process
GO:0005730Cellular Componentnucleolus
GO:0046872Molecular Functionmetal ion binding
Sequence ? help Back to Top
Protein Sequence    Length: 255 aa     Download sequence    Send to blast
MEFWGVEVES GKSLKVTPGD GTLVHISQAC LGNCKNKKGE TVPLYVTVGN QKLVMGTLLS  60
ETIPQLSCDL VFDTEFELSH NWGKGSVHFV GYRTPNVEDG GDYFSDSEEE EEEEEVPATI  120
TVNGSAAKAV VKPKATPAAM EVDEDDSDDE EDSEEEETPK KKPASSKKRA NEAAPNTPVS  180
AKKAKAEVTP KKTEEKKKAG HPATPHPAKK GGKTPTTATQ SPKSASQVSC GSCKKTFNSD  240
NALESHNKAK HAAAK
Functional Description ? help Back to Top
Source Description
UniProtProbably mediates the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Required for histone H3 'Lys-9' deacetylation. Involved in rRNA gene silencing in nucleolar dominance. Seems to be implicated in the regulation of genes involved in seeds development. {ECO:0000269|PubMed:10792817, ECO:0000269|PubMed:12694598, ECO:0000269|PubMed:14992728, ECO:0000269|PubMed:15144374}.
Cis-element ? help Back to Top
SourceLink
PlantRegMapKFK33910.1
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankAF1955459e-40AF195545.1 Arabidopsis thaliana putative histone deacetylase (HD2A) mRNA, complete cds.
GenBankAY0653969e-40AY065396.1 Arabidopsis thaliana putative histone deacetylase (At3g44750) mRNA, complete cds.
GenBankAY0967299e-40AY096729.1 Arabidopsis thaliana putative histone deacetylase (At3g44750) mRNA, complete cds.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_024009551.11e-102histone deacetylase HDT1
SwissprotQ9FVE63e-87HDT1_ARATH; Histone deacetylase HDT1
TrEMBLA0A087GVK80.0A0A087GVK8_ARAAL; Uncharacterized protein
STRINGA0A087GVK80.0(Arabis alpina)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MalvidsOGEM20272667
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT3G44750.21e-51histone deacetylase 3
Publications ? help Back to Top
  1. Song Y,Wu K,Dhaubhadel S,An L,Tian L
    Arabidopsis DNA methyltransferase AtDNMT2 associates with histone deacetylase AtHD2s activity.
    Biochem. Biophys. Res. Commun., 2010. 396(2): p. 187-92
    [PMID:20331964]
  2. Lee K,Park OS,Jung SJ,Seo PJ
    Histone deacetylation-mediated cellular dedifferentiation in Arabidopsis.
    J. Plant Physiol., 2016. 191: p. 95-100
    [PMID:26724747]
  3. Han Z, et al.
    AtHD2D Gene Plays a Role in Plant Growth, Development, and Response to Abiotic Stresses in Arabidopsis thaliana.
    Front Plant Sci, 2016. 7: p. 310
    [PMID:27066015]
  4. Li H, et al.
    Plant-Specific Histone Deacetylases HDT1/2 Regulate GIBBERELLIN 2-OXIDASE2 Expression to Control Arabidopsis Root Meristem Cell Number.
    Plant Cell, 2017. 29(9): p. 2183-2196
    [PMID:28855334]