PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

KFK36649.1

Organism

Arabis alpina

Taxonomic ID

50452

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Arabideae; Arabis

Family

Dof

Protein Properties

Length: 322aa MW: 34627 Da PI: 9.2428

Description

Dof family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
KFK36649.1	genome	MPIPBR	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	zf-Dof	122.9	1.1e-38	81	140	3	62
zf-Dof 3 ekalkcprCdstntkfCyynnyslsqPryfCkaCrryWtkGGalrnvPvGggrrknkkss 62 e alkcprC+stntkfCy+nnysl+qPr+fCk+CrryWt+GGalrnvPvGgg+r+n++++ KFK36649.1 81 EVALKCPRCESTNTKFCYFNNYSLTQPRHFCKTCRRYWTRGGALRNVPVGGGCRRNRRTK 140 5679*****************************************************987 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
ProDom	PD007478	1.0E-33	68	133	IPR003851	Zinc finger, Dof-type
Pfam	PF02701	4.9E-32	83	138	IPR003851	Zinc finger, Dof-type
PROSITE profile	PS50884	29.478	84	138	IPR003851	Zinc finger, Dof-type
PROSITE pattern	PS01361	0	86	122	IPR003851	Zinc finger, Dof-type

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0005634	Cellular Component	nucleus
GO:0044212	Molecular Function	transcription regulatory region DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 322 aa Download sequence Send to blast
MVFSSIQAYL DSSNWQQAPP SNYNQNGQGA SATGGSGGHI LRPQLQPQPQ PLPSNGSGGG 60 GSIRPGSMVD RARQANVAMP EVALKCPRCE STNTKFCYFN NYSLTQPRHF CKTCRRYWTR 120 GGALRNVPVG GGCRRNRRTK SSSSNSTATS NNNASFSSGN ASTISAILSS NYGGNQESIL 180 SQILSPVRLM NPNYNHLGDL TDNNTKTDNN MSLLNYGGLS HQDLRSIQMG TSGGSLMSCV 240 DEWRSTQHPS LGGGNLEDSS NLNPSSNGFY PFESQRITST SISSALASQF SSVKVEDNPY 300 KWVNVNGNCS SWTDLSTFGS SR

Nucleic Localization Signal ? help Back to Top

No.	Start	End	Sequence
1	124	137	RNVPVGGGCRRNRR

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription factor that binds specifically to a 5'-AA[AG]G-3' consensus core sequence (By similarity). Probably involved in early processes for vascular development (PubMed:17583520). The PEAR proteins (e.g. DOF2.4, DOF5.1, DOF3.2, DOF1.1, DOF5.6 and DOF5.3) activate gene expression that promotes radial growth of protophloem sieve elements. Triggers the transcription of HD-ZIP III genes, especially in the central domain of vascular tissue (PubMed:30626969). {ECO:0000250\|UniProtKB:Q9M2U1, ECO:0000269\|PubMed:17583520, ECO:0000269\|PubMed:30626969}.

Binding Motif ? help Back to Top
Motif ID	Method	Source	Motif file
MP00295	DAP	Transfer from AT2G37590	Download

Cis-element ? help Back to Top
Source	Link
PlantRegMap	KFK36649.1

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: By cytokinin in procambium. Antagonized by the HD-ZIP III proteins and by mobile miR165 and miR166 microRNAs. {ECO:0000269\|PubMed:30626969}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	Retrieve

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	AC004684	0.0	AC004684.3 Arabidopsis thaliana chromosome 2 clone F13M22 map ve018, complete sequence.
GenBank	BT030014	0.0	BT030014.1 Arabidopsis thaliana At2g37590 mRNA, complete cds.
GenBank	CP002685	0.0	CP002685.1 Arabidopsis thaliana chromosome 2, complete sequence.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_002879686.1	1e-178	dof zinc finger protein DOF2.4
Swissprot	O80928	1e-167	DOF24_ARATH; Dof zinc finger protein DOF2.4
TrEMBL	A0A087H3E7	0.0	A0A087H3E7_ARAAL; Uncharacterized protein
STRING	A0A087H3E7	0.0	(Arabis alpina)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Malvids	OGEM11354	17	32

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT2G37590.1	1e-127	DNA binding with one finger 2.4

Publications ? help Back to Top
Heyndrickx KS,Vandepoele K Systematic identification of functional plant modules through the integration of complementary data sources. Plant Physiol., 2012. 159(3): p. 884-901 [PMID:22589469] Miyashima S, et al. Mobile PEAR transcription factors integrate positional cues to prime cambial growth. Nature, 2019. 565(7740): p. 490-494 [PMID:30626969]