PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

KFK38436.1

Organism

Arabis alpina

Taxonomic ID

50452

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Arabideae; Arabis

Family

NAC

Protein Properties

Length: 467aa MW: 53004.1 Da PI: 5.406

Description

NAC family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
KFK38436.1	genome	MPIPBR	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	NAM	166.3	1e-51	25	152	1	128
NAM 1 lppGfrFhPtdeelvveyLkkkvegkkleleevikevdiykvePwdLp..kkvkaeekewyfFskrdkkyatgkrknratksgyWkatgkdkevlskkg 97 l+pGfrFhPtdeelv++yLk+kv +k++++ ++i evdiyk ePwdL +++k++++ewyf+s dkky +g r nrat++gyWkatgkd+e+ + + KFK38436.1 25 LAPGFRFHPTDEELVSYYLKRKVLSKPVRF-DAIGEVDIYKNEPWDLAvySRLKTRDQEWYFYSALDKKYGNGARMNRATNKGYWKATGKDREIRR-DI 121 579**********************999.99**********85448899999*********************************9.99 PP NAM 98 elvglkktLvfykgrapkgektdWvmheyrl 128 +l g+kktLvf++grap+g +t+Wvmheyrl KFK38436.1 122 QLLGMKKTLVFHSGRAPDGLRTNWVMHEYRL 152 9**************************98 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SuperFamily	SSF101941	6.67E-59	19	177	IPR003441	NAC domain
PROSITE profile	PS51005	57.028	25	176	IPR003441	NAC domain
Pfam	PF02365	1.6E-26	27	152	IPR003441	NAC domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0009555	Biological Process	pollen development
GO:0010228	Biological Process	vegetative to reproductive phase transition of meristem
GO:0005730	Cellular Component	nucleolus
GO:0003677	Molecular Function	DNA binding
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 467 aa Download sequence Send to blast
MGNESVAVVL SPPPPTGTAT PATSLAPGFR FHPTDEELVS YYLKRKVLSK PVRFDAIGEV 60 DIYKNEPWDL AVYSRLKTRD QEWYFYSALD KKYGNGARMN RATNKGYWKA TGKDREIRRD 120 IQLLGMKKTL VFHSGRAPDG LRTNWVMHEY RLVDYETEAN GNLVQDAYVL CRVFHKNNIG 180 PPSGNRYAPF MEEEWADDRV ALIPGVDVRV QVDPLPLTNG NNQVKVDPLP LTNGNNQSNQ 240 SASKDLININ EPPRETTPMD TETAPMDIET APMDIEPNHQ NHHENALKPE ENNNNNRHDE 300 DEEALKLEQA DEDEQRPPPS LCILNKEAPL PLLQYKRRRQ NESNNNSSRT TQDHCSSTTT 360 TVDNTTTLIS SSAAATNTAI SALLEFSLRG NSDKKENLLR PHKEASTEER LNDMQKEIHQ 420 MSVERETFKL EMMSAEAMIS ILQSRIDALR QENNELRKNN PKGQLVL

Sequence ? help Back to Top

Protein Sequence Length: 467 aa Download sequence Send to blast

MGNESVAVVL SPPPPTGTAT PATSLAPGFR FHPTDEELVS YYLKRKVLSK PVRFDAIGEV  60
DIYKNEPWDL AVYSRLKTRD QEWYFYSALD KKYGNGARMN RATNKGYWKA TGKDREIRRD  120
IQLLGMKKTL VFHSGRAPDG LRTNWVMHEY RLVDYETEAN GNLVQDAYVL CRVFHKNNIG  180
PPSGNRYAPF MEEEWADDRV ALIPGVDVRV QVDPLPLTNG NNQVKVDPLP LTNGNNQSNQ  240
SASKDLININ EPPRETTPMD TETAPMDIET APMDIEPNHQ NHHENALKPE ENNNNNRHDE  300
DEEALKLEQA DEDEQRPPPS LCILNKEAPL PLLQYKRRRQ NESNNNSSRT TQDHCSSTTT  360
TVDNTTTLIS SSAAATNTAI SALLEFSLRG NSDKKENLLR PHKEASTEER LNDMQKEIHQ  420
MSVERETFKL EMMSAEAMIS ILQSRIDALR QENNELRKNN PKGQLVL

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
1ut4_A	2e-45	24	178	16	167	NO APICAL MERISTEM PROTEIN
1ut4_B	2e-45	24	178	16	167	NO APICAL MERISTEM PROTEIN
1ut7_A	2e-45	24	178	16	167	NO APICAL MERISTEM PROTEIN
1ut7_B	2e-45	24	178	16	167	NO APICAL MERISTEM PROTEIN
3swm_A	2e-45	24	178	19	170	NAC domain-containing protein 19
3swm_B	2e-45	24	178	19	170	NAC domain-containing protein 19
3swm_C	2e-45	24	178	19	170	NAC domain-containing protein 19
3swm_D	2e-45	24	178	19	170	NAC domain-containing protein 19
3swp_A	2e-45	24	178	19	170	NAC domain-containing protein 19
3swp_B	2e-45	24	178	19	170	NAC domain-containing protein 19
3swp_C	2e-45	24	178	19	170	NAC domain-containing protein 19
3swp_D	2e-45	24	178	19	170	NAC domain-containing protein 19
4dul_A	2e-45	24	178	16	167	NAC domain-containing protein 19
4dul_B	2e-45	24	178	16	167	NAC domain-containing protein 19
Search in ModeBase

Functional Description ? help Back to Top
Source	Description
UniProt	Transcriptional repressor that binds to the motif 5'-(C/T)A(C/A)G-3' in the promoter of target genes (PubMed:25578968). Binds also to the 5'-CTTGNNNNNCAAG-3' consensus sequence in chromatin (PubMed:26617990). Can bind to the mitochondrial dysfunction motif (MDM) present in the upstream regions of mitochondrial dysfunction stimulon (MDS) genes involved in mitochondrial retrograde regulation (MRR) (PubMed:24045019). Together with NAC050 and JMJ14, regulates gene expression and flowering time by associating with the histone demethylase JMJ14, probably by the promotion of RNA-mediated gene silencing (PubMed:25578968, PubMed:26617990). Regulates siRNA-dependent post-transcriptional gene silencing (PTGS) through SGS3 expression modulation (PubMed:28207953). Required during pollen development (PubMed:19237690). {ECO:0000269\|PubMed:19237690, ECO:0000269\|PubMed:24045019, ECO:0000269\|PubMed:25578968, ECO:0000269\|PubMed:26617990, ECO:0000269\|PubMed:28207953}.

Binding Motif ? help Back to Top
Motif ID	Method	Source	Motif file
MP00612	ChIP-seq	Transfer from AT3G10490	Download

Cis-element ? help Back to Top
Source	Link
PlantRegMap	KFK38436.1

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Induced by type III effector proteins (TTEs) secreted by the pathogenic bacteria P.syringae pv. tomato DC3000 during basal defense. {ECO:0000269\|PubMed:16553893}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	Retrieve

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	AY059795	0.0	AY059795.1 Arabidopsis thaliana unknown protein (At3g10480) mRNA, complete cds.
GenBank	AY091262	0.0	AY091262.1 Arabidopsis thaliana unknown protein (At3g10480) mRNA, complete cds.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_013750304.1	0.0	NAC domain-containing protein 71-like isoform X1
Refseq	XP_013750305.1	0.0	NAC domain-containing protein 71-like isoform X2
Swissprot	Q9SQY0	0.0	NAC52_ARATH; NAC domain containing protein 52
TrEMBL	A0A087H8I4	0.0	A0A087H8I4_ARAAL; Uncharacterized protein
STRING	A0A087H8I5	0.0	(Arabis alpina)

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT3G10490.2	0.0	NAC domain containing protein 52

Publications ? help Back to Top
Higgins JD,Ferdous M,Osman K,Franklin FC The RecQ helicase AtRECQ4A is required to remove inter-chromosomal telomeric connections that arise during meiotic recombination in Arabidopsis. Plant J., 2011. 65(3): p. 492-502 [PMID:21265901] Ding Y, et al. Four distinct types of dehydration stress memory genes in Arabidopsis thaliana. BMC Plant Biol., 2013. 13: p. 229 [PMID:24377444] Zhang S, et al. C-terminal domains of a histone demethylase interact with a pair of transcription factors and mediate specific chromatin association. Cell Discov, 2019. [PMID:26617990] Butel N,Le Masson I,Bouteiller N,Vaucheret H,Elmayan T sgs1: a neomorphic nac52 allele impairing post-transcriptional gene silencing through SGS3 downregulation. Plant J., 2017. 90(3): p. 505-519 [PMID:28207953] Elmayan T, et al. Arabidopsis mutants impaired in cosuppression. Plant Cell, 1998. 10(10): p. 1747-58 [PMID:9761800]