PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID KHN25381.1
Organism
Glycine soja
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Fabales; Fabaceae; Papilionoideae; Phaseoleae; Glycine; Soja
Family bHLH
Protein Properties Length: 404aa    MW: 44399.8 Da    PI: 7.6901
Description bHLH family protein
Gene Model
Gene Model ID Type Source Coding Sequence
KHN25381.1genomeTCUHKView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1HLH28.33.2e-09204251455
                 HHHHHHHHHHHHHHHHHHHHHCTSCCC...TTS-STCHHHHHHHHHHHHHHH CS
         HLH   4 ahnerErrRRdriNsafeeLrellPkaskapskKlsKaeiLekAveYIksLq 55 
                 +h+ +Er RR++i +++  L++l+P +    +k   Ka +L + ++Y++sLq
  KHN25381.1 204 SHSLAERVRREKISERMKYLQDLVPGC----NKVAGKAGMLDEIINYVQSLQ 251
                 8*************************9....677*****************9 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
CDDcd000838.52E-10198255No hitNo description
SuperFamilySSF474597.72E-17198269IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
PROSITE profilePS5088815.37200250IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
Gene3DG3DSA:4.10.280.101.7E-17200267IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
PfamPF000102.0E-6204251IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
SMARTSM003538.7E-10206256IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0046983Molecular Functionprotein dimerization activity
Sequence ? help Back to Top
Protein Sequence    Length: 404 aa     Download sequence    Send to blast
MLHCLNTSCS DITVLERQRE ATIKCQNHQP PYLTDFNVVF PSSSSSSSSS SSSSSSHSQG  60
LLMMCSDSSL GQVLTHSVKP DPGVWPEFGF LPAISRTCSR DGDLVSPKEN MASGKENAKK  120
RKPQNSKVVA EIDNNKDKDK RVKVTGEEGE SKVTEHHTRN KNAKSNANKN NRETSADTSK  180
GSEVQNQKPD YIHVRARRGQ ATDSHSLAER VRREKISERM KYLQDLVPGC NKVAGKAGML  240
DEIINYVQSL QRQVEFLSMK LAAVNPRLDF NIDELFAKEV FPSCAQSFPN IGIPSDMSIS  300
NNPSYLQFNS AQQLVSCCGG LINSMGISPP NMGLRTNIIS TSTVPLPETF LDSSCFAQIL  360
PSSNWEGGDF QSLYNVAFDQ GRTASFPPQP FTGLVEASNL KMEM
Functional Description ? help Back to Top
Source Description
UniProtTranscription factor that binds DNA to G box 5'-CACGTG-3' and, to a lower extent, to E-box 5'-CANNTG-3' in vitro. Binds to chromatin DNA of the FT gene and promotes its expression, and thus triggers flowering in response to blue light. {ECO:0000269|PubMed:18988809, ECO:0000269|PubMed:24130508}.
Cis-element ? help Back to Top
SourceLink
PlantRegMapKHN25381.1
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Accumulates strongly in response to blue light due to reduced preventing 26S proteasome-mediated degradation in an ADO1/ZTL and ADO2/LKP2 dependent manner, but levels decrease in the absence of blue light via 26S proteasome degradation (at protein level). {ECO:0000269|PubMed:24101505}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankBT0983030.0BT098303.1 Soybean clone JCVI-FLGm-23G1 unknown mRNA.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_028195322.10.0transcription factor bHLH63-like isoform X2
SwissprotQ8GY613e-55BH063_ARATH; Transcription factor bHLH63
TrEMBLA0A445HKD00.0A0A445HKD0_GLYSO; Transcription factor bHLH63 isoform B
STRINGGLYMA12G04670.10.0(Glycine max)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
FabidsOGEF36183463
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT4G34530.13e-55cryptochrome-interacting basic-helix-loop-helix 1
Publications ? help Back to Top
  1. Skinner MK,Rawls A,Wilson-Rawls J,Roalson EH
    Basic helix-loop-helix transcription factor gene family phylogenetics and nomenclature.
    Differentiation, 2010. 80(1): p. 1-8
    [PMID:20219281]
  2. Qi X, et al.
    Identification of a novel salt tolerance gene in wild soybean by whole-genome sequencing.
    Nat Commun, 2014. 5: p. 4340
    [PMID:25004933]
  3. Yang D,Zhao W,Meng Y,Li H,Liu B
    A CIB1-LIKE transcription factor GmCIL10 from soybean positively regulates plant flowering.
    Sci China Life Sci, 2015. 58(3): p. 261-9
    [PMID:25651969]
  4. Katsura Y, et al.
    An optogenetic system for interrogating the temporal dynamics of Akt.
    Sci Rep, 2015. 5: p. 14589
    [PMID:26423353]
  5. Taslimi A, et al.
    Optimized second-generation CRY2-CIB dimerizers and photoactivatable Cre recombinase.
    Nat. Chem. Biol., 2016. 12(6): p. 425-30
    [PMID:27065233]
  6. Liu Q, et al.
    The Blue Light-Dependent Polyubiquitination and Degradation of Arabidopsis Cryptochrome2 Requires Multiple E3 Ubiquitin Ligases.
    Plant Cell Physiol., 2016. 57(10): p. 2175-2186
    [PMID:27516416]
  7. Pathak GP, et al.
    Bidirectional approaches for optogenetic regulation of gene expression in mammalian cells using Arabidopsis cryptochrome 2.
    Nucleic Acids Res., 2017. 45(20): p. e167
    [PMID:28431041]
  8. Duan L, et al.
    Understanding CRY2 interactions for optical control of intracellular signaling.
    Nat Commun, 2017. 8(1): p. 547
    [PMID:28916751]
  9. Quejada JR, et al.
    Optimized light-inducible transcription in mammalian cells using Flavin Kelch-repeat F-box1/GIGANTEA and CRY2/CIB1.
    Nucleic Acids Res., 2017. 45(20): p. e172
    [PMID:29040770]
  10. Liu Y, et al.
    CIB1 and CO interact to mediate CRY2-dependent regulation of flowering.
    EMBO Rep., 2019.
    [PMID:30126927]