PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

KZV48983.1

Organism

Dorcoceras hygrometricum

Taxonomic ID

472368

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Lamiales; Gesneriaceae; Didymocarpoideae; Trichosporeae; Loxocarpinae; Dorcoceras

Family

E2F/DP

Protein Properties

Length: 487aa MW: 53192.3 Da PI: 4.7218

Description

E2F/DP family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
KZV48983.1	genome	CNU	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	E2F_TDP	83.3	1.9e-26	161	226	1	71
E2F_TDP 1 rkeksLrlltqkflkllekseegivtlnevakeLvsedvknkrRRiYDilNVLealnliekkekneirwkg 71 r+++sL llt+kf++l++++e+g+++ln++a++L +v ++RRiYDi+NVLe+++liekk kn+i+wkg KZV48983.1 161 RYDSSLSLLTKKFINLIKHAEDGELDLNKAADTL---QV--QKRRIYDITNVLEGIGLIEKKLKNRIHWKG 226 6899****************************...99..**************************98 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Gene3D	G3DSA:1.10.10.10	2.0E-28	158	228	IPR011991	Winged helix-turn-helix DNA-binding domain
SMART	SM01372	8.8E-34	161	226	IPR003316	E2F/DP family, winged-helix DNA-binding domain
SuperFamily	SSF46785	6.8E-17	161	224	IPR011991	Winged helix-turn-helix DNA-binding domain
Pfam	PF02319	2.5E-24	163	226	IPR003316	E2F/DP family, winged-helix DNA-binding domain
CDD	cd14660	1.15E-46	237	343	No hit	No description
SuperFamily	SSF144074	7.59E-33	239	343	No hit	No description
Pfam	PF16421	1.5E-31	242	341	IPR032198	E2F transcription factor, CC-MB domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0005667	Cellular Component	transcription factor complex
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 487 aa Download sequence Send to blast
MAGPGISTRD GAATPPSTAA ENGRIIPLQH TPPTAIRRHL PFASMKPPFA PPDDYHHFST 60 PARAAASDGS TADQLPDAIV VKSTPLKRKN VSGKNEAESN EWTASPGFND IANSPFRTPV 120 SGKGGRPNGR SKVTKNNRSI SSTPISNTDA PSPLTPASSC RYDSSLSLLT KKFINLIKHA 180 EDGELDLNKA ADTLQVQKRR IYDITNVLEG IGLIEKKLKN RIHWKGLDNS KPGEADEDAS 240 LLQAEIENLS MEERDLDERT RQMQEKLRRL SENVHNQKWL FVTEDDIKGL PCFQNETLIA 300 IKAPHGTTLE VPDPDEAVDY PQRRYRIILR STMGPIDVYL VSQFEEKFDE MNGVEQSTSI 360 PVASISGSNE NPAVQSCLPN NCQEIEASGQ ESQGFDSIFA TSQEFAGGMT KIVPSSVGDE 420 TDYWLLSDAD VSITDMWKTD SGIDWNAMDI LHEELNIAAT GATMQLAQPS SSSATADVLT 480 PVDLPPR

Sequence ? help Back to Top

Protein Sequence Length: 487 aa Download sequence Send to blast

MAGPGISTRD GAATPPSTAA ENGRIIPLQH TPPTAIRRHL PFASMKPPFA PPDDYHHFST  60
PARAAASDGS TADQLPDAIV VKSTPLKRKN VSGKNEAESN EWTASPGFND IANSPFRTPV  120
SGKGGRPNGR SKVTKNNRSI SSTPISNTDA PSPLTPASSC RYDSSLSLLT KKFINLIKHA  180
EDGELDLNKA ADTLQVQKRR IYDITNVLEG IGLIEKKLKN RIHWKGLDNS KPGEADEDAS  240
LLQAEIENLS MEERDLDERT RQMQEKLRRL SENVHNQKWL FVTEDDIKGL PCFQNETLIA  300
IKAPHGTTLE VPDPDEAVDY PQRRYRIILR STMGPIDVYL VSQFEEKFDE MNGVEQSTSI  360
PVASISGSNE NPAVQSCLPN NCQEIEASGQ ESQGFDSIFA TSQEFAGGMT KIVPSSVGDE  420
TDYWLLSDAD VSITDMWKTD SGIDWNAMDI LHEELNIAAT GATMQLAQPS SSSATADVLT  480
PVDLPPR

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
1cf7_A	6e-24	156	227	2	74	PROTEIN (TRANSCRIPTION FACTOR E2F-4)
Search in ModeBase

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The binding of retinoblastoma-related proteins represses transactivation. Regulates gene expression both positively and negatively. Activates the expression of E2FB. Involved in the control of cell-cycle progression from G1 to S phase. Stimulates cell proliferation and delays differentiation. {ECO:0000269\|PubMed:11669580, ECO:0000269\|PubMed:11786543, ECO:0000269\|PubMed:11862494, ECO:0000269\|PubMed:11889041, ECO:0000269\|PubMed:11891240, ECO:0000269\|PubMed:12913157, ECO:0000269\|PubMed:15377755, ECO:0000269\|PubMed:16514015, ECO:0000269\|PubMed:19662336}.

Cis-element ? help Back to Top
Source	Link
PlantRegMap	KZV48983.1

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_011094221.1	0.0	transcription factor E2FA
Swissprot	Q9FNY0	1e-154	E2FA_ARATH; Transcription factor E2FA
TrEMBL	A0A2Z7CQD6	0.0	A0A2Z7CQD6_9LAMI; Uncharacterized protein
STRING	XP_009789426.1	0.0	(Nicotiana sylvestris)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Asterids	OGEA1077	24	84

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT2G36010.1	1e-159	E2F transcription factor 3

Publications ? help Back to Top
Magyar Z, et al. Arabidopsis E2FA stimulates proliferation and endocycle separately through RBR-bound and RBR-free complexes. EMBO J., 2012. 31(6): p. 1480-93 [PMID:22307083]