PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Kaladp0039s0564.2.p
Organism
Kalanchoe laxiflora
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; Saxifragales; Crassulaceae; Kalanchoe
Family C2H2
Protein Properties Length: 975aa    MW: 107992 Da    PI: 6.7081
Description C2H2 family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Kaladp0039s0564.2.pgenomeJGIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1zf-C2H211.70.0008939965123
                          EEET..TTTEEESSHHHHHHHHHH..T CS
              zf-C2H2   1 ykCp..dCgksFsrksnLkrHirt..H 23 
                          ykC+   Cg sF+  s++ rH r+  H
  Kaladp0039s0564.2.p 939 YKCKaeGCGVSFRFISDFSRHRRKtgH 965
                          99*********************9777 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PROSITE patternPS000280858882IPR007087Zinc finger, C2H2
SuperFamilySSF576674.63E-7867916No hitNo description
PROSITE profilePS5015712.778879908IPR007087Zinc finger, C2H2
SMARTSM003550.32879903IPR015880Zinc finger, C2H2-like
PROSITE patternPS000280881903IPR007087Zinc finger, C2H2
Gene3DG3DSA:3.30.160.603.3E-6886909IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
PROSITE profilePS5015712.196909938IPR007087Zinc finger, C2H2
SMARTSM003550.002909933IPR015880Zinc finger, C2H2-like
Gene3DG3DSA:3.30.160.604.4E-10910933IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
PROSITE patternPS000280911933IPR007087Zinc finger, C2H2
SuperFamilySSF576678.03E-11919965No hitNo description
Gene3DG3DSA:3.30.160.601.5E-10934962IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
PROSITE profilePS5015710.637939970IPR007087Zinc finger, C2H2
SMARTSM003551.5939965IPR015880Zinc finger, C2H2-like
PROSITE patternPS000280941965IPR007087Zinc finger, C2H2
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0009741Biological Processresponse to brassinosteroid
GO:0009826Biological Processunidimensional cell growth
GO:0033169Biological Processhistone H3-K9 demethylation
GO:0048577Biological Processnegative regulation of short-day photoperiodism, flowering
GO:0048579Biological Processnegative regulation of long-day photoperiodism, flowering
GO:0005634Cellular Componentnucleus
GO:0003676Molecular Functionnucleic acid binding
GO:0046872Molecular Functionmetal ion binding
Sequence ? help Back to Top
Protein Sequence    Length: 975 aa     Download sequence    Send to blast
MNFLPMLSHQ QLLYLLAMSF LTRVPRALLV GARSSRLRDR MKEERELSVK KAFIEDILNE  60
DKLLSVLRGA KSTYRAVLWD PESLPSLSKE PSLLSKMENT AANASDSSNS CVFQSNHNLL  120
DEMRFYTETM KDDYVDDDGF LSDFQVDYGA VACVACGILG FPFMTVVQPS EAASLHLRPL  180
VENKSVAQDI SCLDLDVSID HSVSVLSTPV VSSNMKVNKD QNASHRFFRP RVFCLEHAVQ  240
VIELLESKGG AEVLVICHSD FQKIKSQAAA VAGELGSQYN YDMVPLDCAS LEDLNLIDLA  300
VDEDREESDE DWSSVLGINL RCCIKMRKNS SSKHVDLALK LFGLPSNITL GSSLSHLKWQ  360
HTRSRSKTPV LHDSKQVSKL LSNRIKKEKK IIQYKRRKSK PKSFGSAPVR NTSLDCEENS  420
ASVSSDTDIA GINMSELDNS VNINKSPASM TELNQVEGSL VTPCPSLEIM HSDIVDQLEE  480
SGSVRCVCVS TSVDVVGVDN GVHDTRYKGE TSLNCAVEHS SCADSPVRME GMSASENNGQ  540
IRSTDTTNIK DTIEHEIAIH VDGKNVLTSM EPDLVAGGIP SAANPMLGKT HMDNFTEWEV  600
KDEVCAVIPH NERSNEGSPS LLSQSLTQMS AFEGSSTLLP LASCSTEEYV LVKDTQSSKV  660
ADTPGTEENL CSASLDKLRD NSINAEPAYL VSIETSVGDD SSYEVVQIRT LKGVDDKEDP  720
NNCRLTDFNQ VSLMSAGDES AAAKYMGASK NLYDVKTGET ENNRVKPKPS NRNARKRNRE  780
LEKLRDNKNE VADFIRSPCE GLRPRSKIAS SSHNIDVRHS YTEEPAIAKK KLKHIPADTS  840
TSTPNKTGKQ ESKGWHRCDL ECCILSFKTK AKLLLHQQNQ CHIQGCGKKF SCHRYLIVHQ  900
RVHVDDRPLK CSWKGCNMSF KWAWARTEHL RVHTGERPYK CKAEGCGVSF RFISDFSRHR  960
RKTGHGGDTH SPLG*
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
6a57_A5e-4885696523132Lysine-specific demethylase REF6
6a58_A5e-4885696523132Lysine-specific demethylase REF6
6a59_A5e-4885696523132Lysine-specific demethylase REF6
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtActs probably as a histone 'Lys-4' (H3K4me) demethylase. Involved in transcriptional gene regulation. Acts as a repressor of the photoperiodic flowering pathway and of FT. Binds around the transcription start site of the FT locus. {ECO:0000269|PubMed:15377760, ECO:0000269|PubMed:18467490, ECO:0000269|PubMed:19946624}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_008233302.11e-121PREDICTED: probable lysine-specific demethylase ELF6
SwissprotQ6BDA01e-95ELF6_ARATH; Probable lysine-specific demethylase ELF6
STRINGXP_008233302.11e-120(Prunus mume)
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT5G04240.12e-87C2H2 family protein
Publications ? help Back to Top
  1. Heidari B,Nemie-Feyissa D,Kangasjärvi S,Lillo C
    Antagonistic regulation of flowering time through distinct regulatory subunits of protein phosphatase 2A.
    PLoS ONE, 2013. 8(7): p. e67987
    [PMID:23976921]
  2. Ding Y, et al.
    Four distinct types of dehydration stress memory genes in Arabidopsis thaliana.
    BMC Plant Biol., 2013. 13: p. 229
    [PMID:24377444]
  3. Crevillén P, et al.
    Epigenetic reprogramming that prevents transgenerational inheritance of the vernalized state.
    Nature, 2014. 515(7528): p. 587-90
    [PMID:25219852]
  4. Yang H,Howard M,Dean C
    Physical coupling of activation and derepression activities to maintain an active transcriptional state at FLC.
    Proc. Natl. Acad. Sci. U.S.A., 2016. 113(33): p. 9369-74
    [PMID:27482092]