PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Kaladp0048s0702.3.p
Organism
Kalanchoe laxiflora
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; Saxifragales; Crassulaceae; Kalanchoe
Family bHLH
Protein Properties Length: 378aa    MW: 42416.8 Da    PI: 5.0999
Description bHLH family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Kaladp0048s0702.3.pgenomeJGIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1HLH38.32.4e-12135178654
                          HHHHHHHHHHHHHHHHHHHCTSCC.C...TTS-STCHHHHHHHHHHHHHH CS
                  HLH   6 nerErrRRdriNsafeeLrellPk.askapskKlsKaeiLekAveYIksL 54 
                           e+ErrRR+++N+++ +Lr+l+P  +      Kl+Ka+iL  A+ Y+k+L
  Kaladp0048s0702.3.p 135 LEAERRRRKKLNERLYNLRSLVPIiS------KLDKASILVDAITYVKDL 178
                          589*********************66......****************99 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
CDDcd000839.40E-14126183No hitNo description
PROSITE profilePS5088816.564129178IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
SuperFamilySSF474592.75E-17131194IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
PfamPF000106.3E-10134178IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
SMARTSM003531.6E-14135184IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
Gene3DG3DSA:4.10.280.106.2E-16136194IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
PROSITE profilePS516718.596270342IPR002912ACT domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0008152Biological Processmetabolic process
GO:0048657Biological Processanther wall tapetum cell differentiation
GO:0003677Molecular FunctionDNA binding
GO:0016597Molecular Functionamino acid binding
GO:0046983Molecular Functionprotein dimerization activity
Sequence ? help Back to Top
Protein Sequence    Length: 378 aa     Download sequence    Send to blast
MQEIHATRVL IPVPGALVEL FAAKQVFEDQ QVVDFVMSHC SNQLELQAFF NSGLPSSTHG  60
AHDNGYGMEA MMTHDGSDLP REPSGGHSKD LNEKDSVKPE MGRSDSISDC SDQIDDEDDA  120
GCRKRNGKRP QAKNLEAERR RRKKLNERLY NLRSLVPIIS KLDKASILVD AITYVKDLKK  180
QEKELQDELE ELSNDEDVRN NGTANIEAPT DFMSYPDNLN APNNLLFGAI DSMQPCTLIT  240
RTHEAATEDD KVQQMEPQVE VTLINANKFF IKVFCEHKPG RLVRLLEFLN SLGLEVTNVN  300
VTSCKKLVSN LFEVELKRDS EVVADDLKNS LLELTRIPLS SGWMHDQIPS KPGNGVDIYQ  360
CHHGMMNHHG IPYHLQN*
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
5gnj_A2e-11127179254Transcription factor MYC2
5gnj_B2e-11127179254Transcription factor MYC2
5gnj_E2e-11127179254Transcription factor MYC2
5gnj_F2e-11127179254Transcription factor MYC2
5gnj_G2e-11127179254Transcription factor MYC2
5gnj_I2e-11127179254Transcription factor MYC2
5gnj_M2e-11127179254Transcription factor MYC2
5gnj_N2e-11127179254Transcription factor MYC2
Nucleic Localization Signal ? help Back to Top
NLS
No. Start End Sequence
1122143RKRNGKRPQAKNLEAERRRRKK
2137144ERRRRKKL
Functional Description ? help Back to Top
Source Description
UniProtTranscription factor. Plays a crucial role in tapetum development. Required for male fertility and pollen differentiation, especially during the post-meiotic transcriptional regulation of microspore development within the developing anther (PubMed:12535353). Binds E-box regions in the AHL16/TEK promoter. {ECO:0000269|PubMed:12535353, ECO:0000269|PubMed:24804694}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_015576045.14e-85transcription factor ABORTED MICROSPORES isoform X2
SwissprotQ9ZVX26e-63AMS_ARATH; Transcription factor ABORTED MICROSPORES
TrEMBLA0A2N9FLJ05e-96A0A2N9FLJ0_FAGSY; Uncharacterized protein
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT2G16910.18e-32bHLH family protein
Publications ? help Back to Top
  1. Skinner MK,Rawls A,Wilson-Rawls J,Roalson EH
    Basic helix-loop-helix transcription factor gene family phylogenetics and nomenclature.
    Differentiation, 2010. 80(1): p. 1-8
    [PMID:20219281]
  2. Jiang J,Zhang Z,Cao J
    Pollen wall development: the associated enzymes and metabolic pathways.
    Plant Biol (Stuttg), 2013. 15(2): p. 249-63
    [PMID:23252839]
  3. Xu J, et al.
    ABORTED MICROSPORES Acts as a Master Regulator of Pollen Wall Formation in Arabidopsis.
    Plant Cell, 2014. 26(4): p. 1544-1556
    [PMID:24781116]
  4. Qian H, et al.
    Trace concentrations of imazethapyr (IM) affect floral organs development and reproduction in Arabidopsis thaliana: IM-induced inhibition of key genes regulating anther and pollen biosynthesis.
    Ecotoxicology, 2015. 24(1): p. 163-71
    [PMID:25348600]
  5. Xiong SX, et al.
    The transcription factors MS188 and AMS form a complex to activate the expression of CYP703A2 for sporopollenin biosynthesis in Arabidopsis thaliana.
    Plant J., 2016. 88(6): p. 936-946
    [PMID:27460657]
  6. Ferguson AC, et al.
    Biphasic regulation of the transcription factor ABORTED MICROSPORES (AMS) is essential for tapetum and pollen development in Arabidopsis.
    New Phytol., 2017. 213(2): p. 778-790
    [PMID:27787905]
  7. Lou Y, et al.
    Positive regulation of AMS by TDF1 and the formation of a TDF1-AMS complex are required for anther development in Arabidopsis thaliana.
    New Phytol., 2018. 217(1): p. 378-391
    [PMID:28940573]
  8. Bi H,Fan W,Zhang P
    C4 Protein of Sweet Potato Leaf Curl Virus Regulates Brassinosteroid Signaling Pathway through Interaction with AtBIN2 and Affects Male Fertility in Arabidopsis.
    Front Plant Sci, 2017. 8: p. 1689
    [PMID:29021807]