PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Kaladp0325s0007.2.p
Organism
Kalanchoe laxiflora
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; Saxifragales; Crassulaceae; Kalanchoe
Family WRKY
Protein Properties Length: 379aa    MW: 42692.9 Da    PI: 9.1775
Description WRKY family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Kaladp0325s0007.2.pgenomeJGIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1WRKY104.84.7e-33128185260
                          --SS-EEEEEEE--TT-SS-EEEEEE-STT---EEEEEE-SSSTTEEEEEEES--SS-- CS
                 WRKY   2 dDgynWrKYGqKevkgsefprsYYrCtsagCpvkkkversaedpkvveitYegeHnhek 60 
                          dDgynWrKYGqK+vk+se+prsYY+Ct++gCp+kkkvers  d++++ei+Y+g+Hnh+k
  Kaladp0325s0007.2.p 128 DDGYNWRKYGQKQVKSSENPRSYYKCTFPGCPTKKKVERSL-DGEITEIVYKGSHNHPK 185
                          8****************************************.***************85 PP
2WRKY105.23.5e-33291349159
                          ---SS-EEEEEEE--TT-SS-EEEEEE-STT---EEEEEE-SSSTTEEEEEEES--SS- CS
                 WRKY   1 ldDgynWrKYGqKevkgsefprsYYrCtsagCpvkkkversaedpkvveitYegeHnhe 59 
                          ldDgy+WrKYGqK+vkg+++prsYY+Cts+gC+v+k+ver+++d ++v++tYeg+Hnh+
  Kaladp0325s0007.2.p 291 LDDGYRWRKYGQKVVKGNPNPRSYYKCTSQGCTVRKHVERASHDLRAVITTYEGKHNHD 349
                          59********************************************************7 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:2.20.25.802.7E-29114186IPR003657WRKY domain
SuperFamilySSF1182901.16E-25121186IPR003657WRKY domain
PROSITE profilePS5081123.87122186IPR003657WRKY domain
SMARTSM007746.1E-36127185IPR003657WRKY domain
PfamPF031062.3E-25128184IPR003657WRKY domain
Gene3DG3DSA:2.20.25.803.3E-37276351IPR003657WRKY domain
SuperFamilySSF1182902.62E-29283351IPR003657WRKY domain
PROSITE profilePS5081138.871286351IPR003657WRKY domain
SMARTSM007741.4E-38291350IPR003657WRKY domain
PfamPF031062.1E-25292349IPR003657WRKY domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
GO:0043565Molecular Functionsequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 379 aa     Download sequence    Send to blast
MGKIETYTLH LFFFYSVSLF TAQLLQSPTT GSFPAALSYH WGTLSTQKNA KQEDSRPQNR  60
NNLNNGYSDF TFQPESRTVS ADQQQPWNSG SRPSEQKKDD ISYEQGTGEI VNYQQAQTQS  120
MREARRSDDG YNWRKYGQKQ VKSSENPRSY YKCTFPGCPT KKKVERSLDG EITEIVYKGS  180
HNHPKPKSTR RLSSNSFLPI SAQPMHQIDG DVPERSFGSQ VAPNQSDQSA ATPENSSASV  240
DDDDRSRVGG DEPDAKRWKM ETGGEMMSAT GCRAVQEPRV VVQTTSDIDI LDDGYRWRKY  300
GQKVVKGNPN PRSYYKCTSQ GCTVRKHVER ASHDLRAVIT TYEGKHNHDV PAARGSGSHG  360
RHQQKHGCHD NFQRLIHN*
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1wj2_A4e-37118352878Probable WRKY transcription factor 4
2lex_A4e-37118352878Probable WRKY transcription factor 4
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtTranscription activator (PubMed:26025535). Interacts specifically with the W box (5'-(T)TGAC[CT]-3'), a frequently occurring elicitor-responsive cis-acting element (PubMed:19199048, PubMed:26025535). Negative regulator of both gibberellic acid (GA) and abscisic acid (ABA) signaling in aleurone cells, probably by interfering with GAM1, via the specific repression of GA- and ABA-induced promoters (PubMed:15618416, PubMed:19199048, PubMed:26025535). {ECO:0000269|PubMed:15618416, ECO:0000269|PubMed:19199048, ECO:0000269|PubMed:26025535}.
UniProtTranscription repressor (By similarity). Interacts specifically with the W box (5'-(T)TGAC[CT]-3'), a frequently occurring elicitor-responsive cis-acting element. Negative regulator of both gibberellic acid (GA) and abscisic acid (ABA) signaling in aleurone cells, probably by interfering with GAM1, via the specific repression of GA- and ABA-induced promoters (By similarity). {ECO:0000250|UniProtKB:Q6IEQ7, ECO:0000250|UniProtKB:Q6QHD1}.
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Induced by abscisic acid (ABA) in aleurone cells, embryos, roots and leaves (PubMed:15618416, PubMed:19199048). Slightly down-regulated by gibberellic acid (GA) (PubMed:15618416). Accumulates in response to jasmonic acid (MeJA) (By similarity). {ECO:0000250|UniProtKB:Q6B6R4, ECO:0000269|PubMed:15618416, ECO:0000269|PubMed:19199048}.
UniProtINDUCTION: Induced by abscisic acid (ABA) in aleurone cells, embryos, roots and leaves (PubMed:25110688). Slightly down-regulated by gibberellic acid (GA) (By similarity). Accumulates in response to jasmonic acid (MeJA) (PubMed:16919842). {ECO:0000250|UniProtKB:Q6IEQ7, ECO:0000269|PubMed:16919842, ECO:0000269|PubMed:25110688}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_021279389.11e-127WRKY transcription factor WRKY24 isoform X1
RefseqXP_021279390.11e-128WRKY transcription factor WRKY24 isoform X2
SwissprotQ6B6R41e-115WRK24_ORYSI; WRKY transcription factor WRKY24
SwissprotQ6IEQ71e-115WRK24_ORYSJ; WRKY transcription factor WRKY24
TrEMBLA0A1R3K5U01e-128A0A1R3K5U0_9ROSI; DNA-binding WRKY
STRINGXP_008384716.11e-125(Malus domestica)
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT2G38470.11e-101WRKY DNA-binding protein 33
Publications ? help Back to Top
  1. Kikuchi S, et al.
    Collection, mapping, and annotation of over 28,000 cDNA clones from japonica rice.
    Science, 2003. 301(5631): p. 376-9
    [PMID:12869764]
  2. Zhang ZL, et al.
    A negative regulator encoded by a rice WRKY gene represses both abscisic acid and gibberellins signaling in aleurone cells.
    Plant Mol. Biol., 2009. 70(1-2): p. 139-51
    [PMID:19199048]
  3. Basu S,Roychoudhury A
    Expression profiling of abiotic stress-inducible genes in response to multiple stresses in rice (Oryza sativa L.) varieties with contrasting level of stress tolerance.
    Biomed Res Int, 2014. 2014: p. 706890
    [PMID:25110688]
  4. Zhang L, et al.
    Three WRKY transcription factors additively repress abscisic acid and gibberellin signaling in aleurone cells.
    Plant Sci., 2015. 236: p. 214-22
    [PMID:26025535]