PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

Kalax.0045s0142.2.p

Organism

Kalanchoe marnieriana

Taxonomic ID

80907

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; Saxifragales; Crassulaceae; Kalanchoe

Family

C2H2

Protein Properties

Length: 1056aa MW: 116572 Da PI: 6.9857

Description

C2H2 family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Kalax.0045s0142.2.p	genome	JGI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	zf-C2H2	11.6	0.00088	1020	1046	1	23
EEET..TTTEEESSHHHHHHHHHH..T CS zf-C2H2 1 ykCp..dCgksFsrksnLkrHirt..H 23 ykC+ Cg sF+ s++ rH r+ H Kalax.0045s0142.2.p 1020 YKCKaeGCGVSFRFISDFSRHRRKtgH 1046 99*********************9777 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
PROSITE profile	PS51184	16.031	1	73	IPR003347	JmjC domain
Pfam	PF02373	8.5E-16	3	56	IPR003347	JmjC domain
SuperFamily	SSF51197	1.21E-9	8	69	No hit	No description
PROSITE pattern	PS00028	0	939	963	IPR007087	Zinc finger, C2H2
SuperFamily	SSF57667	4.57E-7	948	997	No hit	No description
SMART	SM00355	0.32	960	984	IPR015880	Zinc finger, C2H2-like
PROSITE profile	PS50157	12.778	960	989	IPR007087	Zinc finger, C2H2
PROSITE pattern	PS00028	0	962	984	IPR007087	Zinc finger, C2H2
Gene3D	G3DSA:3.30.160.60	3.3E-6	967	990	IPR013087	Zinc finger C2H2-type/integrase DNA-binding domain
PROSITE profile	PS50157	12.196	990	1019	IPR007087	Zinc finger, C2H2
SMART	SM00355	0.002	990	1014	IPR015880	Zinc finger, C2H2-like
Gene3D	G3DSA:3.30.160.60	4.8E-10	991	1014	IPR013087	Zinc finger C2H2-type/integrase DNA-binding domain
PROSITE pattern	PS00028	0	992	1014	IPR007087	Zinc finger, C2H2
SuperFamily	SSF57667	9.1E-11	1000	1046	No hit	No description
Gene3D	G3DSA:3.30.160.60	1.6E-10	1015	1043	IPR013087	Zinc finger C2H2-type/integrase DNA-binding domain
PROSITE profile	PS50157	10.637	1020	1051	IPR007087	Zinc finger, C2H2
SMART	SM00355	1.5	1020	1046	IPR015880	Zinc finger, C2H2-like
PROSITE pattern	PS00028	0	1022	1046	IPR007087	Zinc finger, C2H2

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0009741	Biological Process	response to brassinosteroid
GO:0009826	Biological Process	unidimensional cell growth
GO:0033169	Biological Process	histone H3-K9 demethylation
GO:0048577	Biological Process	negative regulation of short-day photoperiodism, flowering
GO:0048579	Biological Process	negative regulation of long-day photoperiodism, flowering
GO:0005634	Cellular Component	nucleus
GO:0003676	Molecular Function	nucleic acid binding
GO:0046872	Molecular Function	metal ion binding

Sequence ? help Back to Top
Protein Sequence Length: 1056 aa Download sequence Send to blast
MMLGEKTTLL SPEVVVASGI PCCRLVQNPG EFVVTFPRAY HVGFSHGFNC GEAANFGTPQ 60 WLKVAKEAAV RRAAMNFLPM LSHQQLLYLL AMSFLTRVPR ALLVGARSSR LRDRMKEERE 120 LSVKKAFIED ILNEDKLLSV LRGAKSTYRA VLWDPESLPS LSKEPSLLSK MENTAANASD 180 SSNSCVFQSN HNLLDEMRFY TETMKDDYVD DDGFLSDFQV DYGAVACVAC GILGFPFMTV 240 VQPSEAASLH LRPLLENKSV AQDGSCLDLD VSIDHSISVL SKPVVSSNMK VNKEQNASHR 300 FFRPRVFCLE HAVQVIELLE SKGGAEVLVI CHSDFQKIKS HAAAVAGELG SKYNYDMVPL 360 DCASLEDLNL IDLAVDEDRE ESDEDWSSVL GINLRCCIKM RKNSSSKHVD LALKLFGLPS 420 NITLGSSLSR LKWQHTRSRS KTPILHDSKQ LSKLVSNGIK KEKKIIQYKR RKSKPKSFGS 480 APVRNTSLDC EDNSASVSSD TDIAGISMSE LDNSVDINKS PASMTVLNQV EGSLVTPCPS 540 LEIMHSNIVD QLEESGSVRC VCVSTSVDVV GADNGVHDTR YKGETSLNCA VEHSSCADSP 600 VRMEGMSASE NNGQIRSTDT TNIKDTIEHE IAIHVDGKNV LTSMEPDLVA GGIPSAANPM 660 RGKTHMDNFP EWEVKDEVCA VIPYNERSNE GSPSLLSQSL TQMSAFEGSS TLLPLASCST 720 EEYVLVKDTR NSKVADTPGT EENLCSGSLD KLRDNSINAE PAYLVSIETS VGDDSSYEVV 780 QIRTLKGVDD KEDPNNRRLT DFNQVSLMSA GDESAAAKYM GASKDLYDVD PVCSPAKTGE 840 TENNRVKPKP SNRNARKRNR ELEKLRDNKN EVADFIRSPC EGLRPRSKIA SSSHNIDVRH 900 SYTEEPAIAK KKLKQIPADT STSTPDRTGK QELKGSHRCD LECCILSFKT KAKLLLHQQN 960 QCHIQGCGKK FSCHRYLIVH QRVHVDDRPL KCSWKGCNMS FKWAWARTEH LRVHTGERPY 1020 KCKAEGCGVS FRFISDFSRH RRKTGHGGDT HSPLG*

Sequence ? help Back to Top

Protein Sequence Length: 1056 aa Download sequence Send to blast

MMLGEKTTLL SPEVVVASGI PCCRLVQNPG EFVVTFPRAY HVGFSHGFNC GEAANFGTPQ  60
WLKVAKEAAV RRAAMNFLPM LSHQQLLYLL AMSFLTRVPR ALLVGARSSR LRDRMKEERE  120
LSVKKAFIED ILNEDKLLSV LRGAKSTYRA VLWDPESLPS LSKEPSLLSK MENTAANASD  180
SSNSCVFQSN HNLLDEMRFY TETMKDDYVD DDGFLSDFQV DYGAVACVAC GILGFPFMTV  240
VQPSEAASLH LRPLLENKSV AQDGSCLDLD VSIDHSISVL SKPVVSSNMK VNKEQNASHR  300
FFRPRVFCLE HAVQVIELLE SKGGAEVLVI CHSDFQKIKS HAAAVAGELG SKYNYDMVPL  360
DCASLEDLNL IDLAVDEDRE ESDEDWSSVL GINLRCCIKM RKNSSSKHVD LALKLFGLPS  420
NITLGSSLSR LKWQHTRSRS KTPILHDSKQ LSKLVSNGIK KEKKIIQYKR RKSKPKSFGS  480
APVRNTSLDC EDNSASVSSD TDIAGISMSE LDNSVDINKS PASMTVLNQV EGSLVTPCPS  540
LEIMHSNIVD QLEESGSVRC VCVSTSVDVV GADNGVHDTR YKGETSLNCA VEHSSCADSP  600
VRMEGMSASE NNGQIRSTDT TNIKDTIEHE IAIHVDGKNV LTSMEPDLVA GGIPSAANPM  660
RGKTHMDNFP EWEVKDEVCA VIPYNERSNE GSPSLLSQSL TQMSAFEGSS TLLPLASCST  720
EEYVLVKDTR NSKVADTPGT EENLCSGSLD KLRDNSINAE PAYLVSIETS VGDDSSYEVV  780
QIRTLKGVDD KEDPNNRRLT DFNQVSLMSA GDESAAAKYM GASKDLYDVD PVCSPAKTGE  840
TENNRVKPKP SNRNARKRNR ELEKLRDNKN EVADFIRSPC EGLRPRSKIA SSSHNIDVRH  900
SYTEEPAIAK KKLKQIPADT STSTPDRTGK QELKGSHRCD LECCILSFKT KAKLLLHQQN  960
QCHIQGCGKK FSCHRYLIVH QRVHVDDRPL KCSWKGCNMS FKWAWARTEH LRVHTGERPY  1020
KCKAEGCGVS FRFISDFSRH RRKTGHGGDT HSPLG*

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
6a57_A	6e-48	935	1046	21	132	Lysine-specific demethylase REF6
6a58_A	6e-48	935	1046	21	132	Lysine-specific demethylase REF6
6a59_A	6e-48	935	1046	21	132	Lysine-specific demethylase REF6
Search in ModeBase

Functional Description ? help Back to Top
Source	Description
UniProt	Acts probably as a histone 'Lys-4' (H3K4me) demethylase. Involved in transcriptional gene regulation. Acts as a repressor of the photoperiodic flowering pathway and of FT. Binds around the transcription start site of the FT locus. {ECO:0000269\|PubMed:15377760, ECO:0000269\|PubMed:18467490, ECO:0000269\|PubMed:19946624}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_020412564.1	1e-174	probable lysine-specific demethylase ELF6
Swissprot	Q6BDA0	1e-150	ELF6_ARATH; Probable lysine-specific demethylase ELF6
STRING	XP_008233302.1	1e-173	(Prunus mume)

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT5G04240.1	1e-133	C2H2 family protein

Link Out ? help Back to Top
Phytozome	Kalax.0045s0142.2.p

Publications ? help Back to Top
Heidari B,Nemie-Feyissa D,Kangasjärvi S,Lillo C Antagonistic regulation of flowering time through distinct regulatory subunits of protein phosphatase 2A. PLoS ONE, 2013. 8(7): p. e67987 [PMID:23976921] Ding Y, et al. Four distinct types of dehydration stress memory genes in Arabidopsis thaliana. BMC Plant Biol., 2013. 13: p. 229 [PMID:24377444] Crevillén P, et al. Epigenetic reprogramming that prevents transgenerational inheritance of the vernalized state. Nature, 2014. 515(7528): p. 587-90 [PMID:25219852] Yang H,Howard M,Dean C Physical coupling of activation and derepression activities to maintain an active transcriptional state at FLC. Proc. Natl. Acad. Sci. U.S.A., 2016. 113(33): p. 9369-74 [PMID:27482092]