PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Kalax.0106s0030.1.p
Organism
Kalanchoe marnieriana
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; Saxifragales; Crassulaceae; Kalanchoe
Family C2H2
Protein Properties Length: 373aa    MW: 42388 Da    PI: 6.7589
Description C2H2 family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Kalax.0106s0030.1.pgenomeJGIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1zf-C2H216.52.4e-05106130123
                          EEET..TTTEEESSHHHHHHHHHHT CS
              zf-C2H2   1 ykCp..dCgksFsrksnLkrHirtH 23 
                          y+C+   Cgk F ++s LkrH   H
  Kalax.0106s0030.1.p 106 YVCHyeGCGKKFLDSSKLKRHFLIH 130
                          9********************8877 PP
2zf-C2H222.33.4e-07136160123
                          EEET..TTTEEESSHHHHHHHHHHT CS
              zf-C2H2   1 ykCp..dCgksFsrksnLkrHirtH 23 
                          ykCp   Cgk Fs   nLk+H++tH
  Kalax.0106s0030.1.p 136 YKCPheGCGKAFSLDFNLKSHMKTH 160
                          9***********************9 PP
3zf-C2H214.30.00012167190223
                          EET..TTTEEESSHHHHHHHHHHT CS
              zf-C2H2   2 kCp..dCgksFsrksnLkrHirtH 23 
                           Cp   Cgk++ + + L++H+++H
  Kalax.0106s0030.1.p 167 LCPfpECGKRYAHEYKLNNHLSSH 190
                          59999******************6 PP
4zf-C2H214.50.0001230254123
                          EEET..TTTEEESSHHHHHHHHHHT CS
              zf-C2H2   1 ykCp..dCgksFsrksnLkrHirtH 23 
                          y Cp   C+k + + + L+ H+r+H
  Kalax.0106s0030.1.p 230 YACPydGCDKAYIHEYKLNLHLRNH 254
                          89**********************6 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:3.30.160.601.9E-1372103IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
SMARTSM003550.005777101IPR015880Zinc finger, C2H2-like
PROSITE profilePS5015710.51277106IPR007087Zinc finger, C2H2
SuperFamilySSF576675.5E-879130No hitNo description
PROSITE patternPS00028079101IPR007087Zinc finger, C2H2
Gene3DG3DSA:3.30.160.602.3E-14104126IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
SMARTSM003550.0024106130IPR015880Zinc finger, C2H2-like
PROSITE profilePS5015713.962106135IPR007087Zinc finger, C2H2
PROSITE patternPS000280108130IPR007087Zinc finger, C2H2
SuperFamilySSF576672.71E-15117170No hitNo description
Gene3DG3DSA:3.30.160.602.6E-20127161IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
SMARTSM003551.2E-4136160IPR015880Zinc finger, C2H2-like
PROSITE profilePS5015712.757136165IPR007087Zinc finger, C2H2
PROSITE patternPS000280138160IPR007087Zinc finger, C2H2
Gene3DG3DSA:3.30.160.603.2E-7162191IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
SMARTSM003550.06166190IPR015880Zinc finger, C2H2-like
PROSITE profilePS5015710.803166196IPR007087Zinc finger, C2H2
PROSITE patternPS000280168191IPR007087Zinc finger, C2H2
Gene3DG3DSA:3.30.160.606.2E-10222254IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
SuperFamilySSF576671.76E-6225255No hitNo description
SMARTSM003550.0038230254IPR015880Zinc finger, C2H2-like
PROSITE profilePS501579.265230254IPR007087Zinc finger, C2H2
PROSITE patternPS000280232255IPR007087Zinc finger, C2H2
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0045892Biological Processnegative regulation of transcription, DNA-templated
GO:0045893Biological Processpositive regulation of transcription, DNA-templated
GO:0005634Cellular Componentnucleus
GO:0043565Molecular Functionsequence-specific DNA binding
GO:0046872Molecular Functionmetal ion binding
Sequence ? help Back to Top
Protein Sequence    Length: 373 aa     Download sequence    Send to blast
MEPHAGYGLF DNRRPMGYNP RAPAVRWVKE WVPQEVVATG GKCSLLKWVN EHTLKALRER  60
ENEIDVAEPE PTTEVLFLCS FEGCGKTFFD VGALRKHAHI HGERQYVCHY EGCGKKFLDS  120
SKLKRHFLIH TGERAYKCPH EGCGKAFSLD FNLKSHMKTH SQDNYYLCPF PECGKRYAHE  180
YKLNNHLSSH HDKVEPELPK YMATPVAEKP PKPSKPTPTP SSQPSSDRPY ACPYDGCDKA  240
YIHEYKLNLH LRNHHPNHFA DENADQDEAD EPGSQNVYSS KRASTKRQKP SKAQPPKSGA  300
KTSSSKSAKR KASAPAAPVV VKKPWPVKEE PNREEDSEET EEDRDNVEGG WRYQENNNMD  360
DDEGDEETED EN*
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1ubd_C2e-34791908119PROTEIN (YY1 ZINC FINGER DOMAIN)
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtDual-function transcription factor with both repression and activation activities. Binds to 5'-CCATATT-3' motif in target gene promoters (e.g. ABR1) (PubMed:26961720). Binds also to G-rich DNA motif 5'-GGGGGCAGTGG-3' (PubMed:22508367). Regulates the expression of genes involved in diverse cellular pathways, including glucose metabolism, photosynthesis, phototropism and stress response (e.g. salt, drought and osmotic stress) (PubMed:22508367, PubMed:26961720). Regulates plant immunity, especially during necrotrophic fungal infection (e.g. B.cinerea) (PubMed:24451981). Binds to ABR1 promoter and promotes its expression, thus negatively regulating the abscisic acid (ABA) signaling pathway. Represses ABA- and salt-responsive genes expression (PubMed:26961720). {ECO:0000269|PubMed:22508367, ECO:0000269|PubMed:24451981, ECO:0000269|PubMed:26961720}.
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Induced by abscisic acid (ABA) in an ABI1- and ABI4-dependent manner. Stimulated by stress conditions including high salt, osmotic stress (e.g. mannitol) and dehydration. May be induced by ABI4 but repressed by ABR1. Repressed by darkness but induced by light. {ECO:0000269|PubMed:26961720}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_022897013.11e-150zinc finger transcription factor YY1
SwissprotQ2V3L31e-126YY1_ARATH; Zinc finger transcription factor YY1
TrEMBLA0A396J0E01e-147A0A396J0E0_MEDTR; Putative transcription factor C2H2 family
STRINGPGSC0003DMT4000234591e-147(Solanum tuberosum)
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT4G06634.11e-101C2H2 family protein
Publications ? help Back to Top
  1. Kumekawa N,Hosouchi T,Tsuruoka H,Kotani H
    The size and sequence organization of the centromeric region of Arabidopsis thaliana chromosome 4.
    DNA Res., 2001. 8(6): p. 285-90
    [PMID:11853315]
  2. Li T,Wu XY,Li H,Song JH,Liu JY
    A Dual-Function Transcription Factor, AtYY1, Is a Novel Negative Regulator of the Arabidopsis ABA Response Network.
    Mol Plant, 2016. 9(5): p. 650-661
    [PMID:26961720]
  3. Wu XY,Li T
    A Casein Kinase II Phosphorylation Site in AtYY1 Affects Its Activity, Stability, and Function in the ABA Response.
    Front Plant Sci, 2017. 8: p. 323
    [PMID:28348572]