PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Kalax.0175s0027.1.p
Organism
Kalanchoe marnieriana
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; Saxifragales; Crassulaceae; Kalanchoe
Family ARF
Protein Properties Length: 767aa    MW: 86104.5 Da    PI: 6.6546
Description ARF family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Kalax.0175s0027.1.pgenomeJGIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1B371.88.9e-23125226199
                          EEEE-..-HHHHTT-EE--HHH.HTT......---..--SEEEEEETTS-EEEEEE..EEETTEEEE-TTHHHHHHHHT--TT-EEEEEE CS
                   B3   1 ffkvltpsdvlksgrlvlpkkfaeeh......ggkkeesktltledesgrsWevkliyrkksgryvltkGWkeFvkangLkegDfvvFkl 84 
                          f+k+lt sd++++g +++p++ ae+       +++++  ++l+ +d++  +W++++i+r++++r++lt+GW+ Fv+a++L +gD v+F  
  Kalax.0175s0027.1.p 125 FCKTLTASDTSTHGGFSVPRRAAEKVfppldfSLQPPA-QELIAKDLHDVEWKFRHIFRGQPKRHLLTTGWSVFVSAKRLVAGDAVLFI- 212
                          99*****************************9777666.49************************************************. PP

                          -SSSEE..EEEEE-S CS
                   B3  85 dgrsefelvvkvfrk 99 
                           ++++ +l+++++r+
  Kalax.0175s0027.1.p 213 -WNERNQLLLGIRRA 226
                          .7888889****997 PP
2Auxin_resp116.42.5e-38251334183
           Auxin_resp   1 aahaastksvFevvYnPrastseFvvkvekvekalk.vkvsvGmRfkmafetedsserrlsGtvvgvsdldpvrWpnSkWrsLk 83 
                          aahaa+t+s F+++YnPra++seFv++++k++ka+  ++vsvGmRf+m fete+ss rr++Gt+++++d+dp rWpnS+Wrs+k
  Kalax.0175s0027.1.p 251 AAHAAATNSCFTIFYNPRACPSEFVIPLSKYVKAVFhTRVSVGMRFRMLFETEESSVRRYMGTITSINDIDPARWPNSHWRSVK 334
                          79********************************87599******************************************985 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SuperFamilySSF1019364.97E-48109254IPR015300DNA-binding pseudobarrel domain
Gene3DG3DSA:2.40.330.101.0E-40118240IPR015300DNA-binding pseudobarrel domain
CDDcd100172.55E-21124225No hitNo description
PfamPF023623.8E-21125226IPR003340B3 DNA binding domain
SMARTSM010192.2E-22125227IPR003340B3 DNA binding domain
PROSITE profilePS5086312.196125227IPR003340B3 DNA binding domain
PfamPF065072.1E-33251334IPR010525Auxin response factor
SuperFamilySSF542774.27E-7691766No hitNo description
PROSITE profilePS5174524.437698766IPR000270PB1 domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0009725Biological Processresponse to hormone
GO:0005634Cellular Componentnucleus
GO:0003677Molecular FunctionDNA binding
GO:0005515Molecular Functionprotein binding
Sequence ? help Back to Top
Protein Sequence    Length: 767 aa     Download sequence    Send to blast
MKLSASSGIA HDGDNRCLNS QLWHACAGPL VSLPTAGSRV VYFPQGHSEQ VAATTNRDVD  60
GQIPNYPSLP PQLICQLHNV TMHADVETDE VYAQMTLQPL SLQEQEVTYL PMEFGIPSKQ  120
PTNYFCKTLT ASDTSTHGGF SVPRRAAEKV FPPLDFSLQP PAQELIAKDL HDVEWKFRHI  180
FRGQPKRHLL TTGWSVFVSA KRLVAGDAVL FIWNERNQLL LGIRRATRPQ TAMPSSVLSS  240
DSMHIGLLAA AAHAAATNSC FTIFYNPRAC PSEFVIPLSK YVKAVFHTRV SVGMRFRMLF  300
ETEESSVRRY MGTITSINDI DPARWPNSHW RSVKVGWDES TAAERQPRVS LWDIEPLTTF  360
PMYPSLFPFR MKRPWYPGVS SFQDHRDEAA GASLYSDHGR QALNFQHVGM FPYMQSRIDP  420
SLFGHNQDHY QPIMASGLVN TENGGHLKQQ FMHFNRPLQS HQVPDGSNAQ LQQLNKIGQQ  480
ASTQSVMHGQ TISTENLPTH FLQQQLNNQL KEVQQPSKQM YQQETQNQIE QFRQRHQLDM  540
GSSSVPKQEF TNSRTNFERQ ENASSRHNVL DSPGDGSSLM YVDQLSQQFY RPKFLHSEGA  600
SFAHSLSLSP YLEKDAASEP DTRNPVNRSH SSYGVNIDSS GLIMPTNVPI FTGSPIDAKA  660
SSVPPEDSSV FQGSMYGGRQ DSPNLYCVGQ FGSPLTSQIF VKVYKSGSVG RSLDISRFSS  720
YDELREELGQ MFDIEGHLDD PLRSGWQLVF VDRENDVLLL GDDPWE*
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
4ldu_A1e-1601835551388Auxin response factor 5
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtAuxin response factors (ARFs) are transcriptional factors that bind specifically to the DNA sequence 5'-TGTCTC-3' found in the auxin-responsive promoter elements (AuxREs). Seems to act as transcriptional activator. Formation of heterodimers with Aux/IAA proteins may alter their ability to modulate early auxin response genes expression. Regulates both stamen and gynoecium maturation. Promotes jasmonic acid production. Partially redundant with ARF6. Involved in fruit initiation. Acts as an inhibitor to stop further carpel development in the absence of fertilization and the generation of signals required to initiate fruit and seed development. {ECO:0000269|PubMed:12036261, ECO:0000269|PubMed:16107481, ECO:0000269|PubMed:16829592}.
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Repressed by miR167. {ECO:0000269|PubMed:17021043}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_002266678.20.0PREDICTED: auxin response factor 8
SwissprotQ9FGV10.0ARFH_ARATH; Auxin response factor 8
TrEMBLA0A498HAH80.0A0A498HAH8_MALDO; Auxin response factor
STRINGXP_004288582.10.0(Fragaria vesca)
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT5G37020.20.0auxin response factor 8
Publications ? help Back to Top
  1. Liu N, et al.
    Down-regulation of AUXIN RESPONSE FACTORS 6 and 8 by microRNA 167 leads to floral development defects and female sterility in tomato.
    J. Exp. Bot., 2014. 65(9): p. 2507-20
    [PMID:24723401]
  2. Minato N, et al.
    The phytoplasmal virulence factor TENGU causes plant sterility by downregulating of the jasmonic acid and auxin pathways.
    Sci Rep, 2014. 4: p. 7399
    [PMID:25492247]
  3. Ortega-Amaro MA, et al.
    Overexpression of AtGRDP2, a novel glycine-rich domain protein, accelerates plant growth and improves stress tolerance.
    Front Plant Sci, 2014. 5: p. 782
    [PMID:25653657]
  4. Wang Y, et al.
    MicroRNA167-Directed Regulation of the Auxin Response Factors GmARF8a and GmARF8b Is Required for Soybean Nodulation and Lateral Root Development.
    Plant Physiol., 2015. 168(3): p. 984-99
    [PMID:25941314]
  5. Barik S, et al.
    Coevolution Pattern and Functional Conservation or Divergence of miR167s and their targets across Diverse Plant Species.
    Sci Rep, 2015. 5: p. 14611
    [PMID:26459056]
  6. Pashkovskiy PP,Kartashov AV,Zlobin IE,Pogosyan SI,Kuznetsov VV
    Blue light alters miR167 expression and microRNA-targeted auxin response factor genes in Arabidopsis thaliana plants.
    Plant Physiol. Biochem., 2016. 104: p. 146-54
    [PMID:27031426]
  7. Mlotshwa S,Pruss GJ,MacArthur JL,Reed JW,Vance V
    Developmental Defects Mediated by the P1/HC-Pro Potyviral Silencing Suppressor Are Not Due to Misregulation of AUXIN RESPONSE FACTOR 8.
    Plant Physiol., 2016. 172(3): p. 1853-1861
    [PMID:27688620]
  8. Wójcikowska B,Gaj MD
    Expression profiling of AUXIN RESPONSE FACTOR genes during somatic embryogenesis induction in Arabidopsis.
    Plant Cell Rep., 2017. 36(6): p. 843-858
    [PMID:28255787]
  9. Zhang GZ, et al.
    Ectopic expression of UGT84A2 delayed flowering by indole-3-butyric acid-mediated transcriptional repression of ARF6 and ARF8 genes in Arabidopsis.
    Plant Cell Rep., 2017. 36(12): p. 1995-2006
    [PMID:29027578]
  10. Zheng K, et al.
    Involvement of PACLOBUTRAZOL RESISTANCE6/KIDARI, an Atypical bHLH Transcription Factor, in Auxin Responses in Arabidopsis.
    Front Plant Sci, 2017. 8: p. 1813
    [PMID:29114256]
  11. Liu Z, et al.
    ARF2-ARF4 and ARF5 are Essential for Female and Male Gametophyte Development in Arabidopsis.
    Plant Cell Physiol., 2018. 59(1): p. 179-189
    [PMID:29145642]
  12. Ghelli R, et al.
    A Newly Identified Flower-Specific Splice Variant of AUXIN RESPONSE FACTOR8 Regulates Stamen Elongation and Endothecium Lignification in Arabidopsis.
    Plant Cell, 2018. 30(3): p. 620-637
    [PMID:29514943]